Potential advancement utilizing nanotechnology-based delivery system to enhance the therapeutic properties of lavender essential oil: a review article DOI Creative Commons

A.M. Bagas Trianloka,

Lutfi Chabib,

Arba Pramundita Ramadani

et al.

Jurnal Ilmiah Farmasi (Scientific Journal of Pharmacy), Journal Year: 2024, Volume and Issue: 20(2), P. 231 - 243

Published: Dec. 31, 2024

Background: Essential oils (EO), such as lavender (Lavandula spp.), which are derived from its flower, have become a growing trend in recent years an alternative medicine therapy. However, the poor physicochemical properties of EOs several disadvantages for their application. Integrating nanotechnology into formulation medicinal dosage forms may provide viable way to mitigate these limitations and improve effectiveness EO utilization.Objective: This literature review aims gather information on benefits prospective applications nanotechnology-based delivery systems EOs.Method: Online databases PubMed, Science Direct, Research Gate, Google Scholar, other reliable sources were used find 65 publications between 1991 2021, assessed this review.Results: It is revealed that main constituents linalool, linalyl acetate, lavandulyl acetate. Its antibacterial, antioxidant, anticancer, anti-anxiety, having effects central nervous system, along with qualities including pain relief, has been demonstrated via numerous studies. Additionally, it was dermatological helped treat dermatitis encouraged both hair growth wound healing. Furthermore, also found application improved concentration active compounds blood produced stable form while increasing efficacy.Conclusion: feasible create nanoparticle can substance's solubility, stability, pharmacological effects. More research necessary formulate by applying nanotechnology.

Language: Английский

Lipid Nanoparticles Carrying Essential Oils for Multiple Applications as Antimicrobials DOI Creative Commons

Elenice Francisco da Silva,

Fernanda Aparecida Longato dos Santos,

Henrique Machado Pires

et al.

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(2), P. 178 - 178

Published: Jan. 31, 2025

Lipid nanoparticles (LNPs) are versatile delivery systems with high interest because they allow the release of hydrophobic and hydrophilic molecules, such as essential oils (EOs) plant extracts. This review covers published works between 2019 2024 that have reported use EO-based LNPs antimicrobial properties applications in human animal health, well biopesticides. In healthcare field, reports addressed effect encapsulating EOs lipid nanosystems antiviral, antibacterial, antiprotozoal antifungal activities. care, this still needs to be more deeply explored while looking for sustainable alternatives against different types parasites affect health. Overall, antibacterial activities carrying described synthetic antibiotics. field agriculture, studies showed these approaches control phytopathogens other pests food production. There is a growing demand innovative technologies. However, there some challenges overcome order innovations reach market.

Language: Английский

Citations

0
Nano-encapsulated Melissa officinalis Essential Oil and Its Antibacterial Effects Against Multi Drug Resistant E. coli and K. pneumonia DOI

Fereshteh Lotfi,

Mehran Nemattalab, Zahra Hesari

et al.

Current Microbiology, Journal Year: 2025, Volume and Issue: 82(6)

Published: May 2, 2025

Language: Английский

Citations

0
Re-purposing of Linagliptin for enhanced wound healing and skin rejuvenation via chitosan- modified PLGA Nanoplatforms DOI
Fatma Sa’eed El-Tokhy, Dina O Helal, Sherif S. Abdel Mageed

et al.

International Journal of Pharmaceutics, Journal Year: 2025, Volume and Issue: 677, P. 125664 - 125664

Published: May 1, 2025

Language: Английский

Citations

0
Skin Recovery by Lavandula angustifolia Leaf Callus Extract: Redox Control of Nrf2 Signaling DOI
E. Kim, Sooyun Kim,

Jihyeok Song

et al.

Free Radical Biology and Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: May 1, 2025

Language: Английский

Citations

0
SLN and chitosan nano-delivery systems for antibacterial effect of black seed ( Nigella sativa) oil against S. aureus DOI

Mahdis Payamifard,

Mehran Nemattalab, Leila Rezaie Shirmard

et al.

International Journal of Environmental Health Research, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 12

Published: July 21, 2024

with current universal importance represents a main carrier of emerging antimicrobial resistance determinatives global health concerns that have developed drug mechanisms to the various available antibiotics. On other hand, due potential

Language: Английский

Citations

2
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for the delivery of bioactives sourced from plants: part II – applications and preclinical advancements DOI
Faezeh Fathi, Tatiane de Oliveira Xavier Machado,

Helena A. C. Kodel

et al.

Expert Opinion on Drug Delivery, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

Numerous purified bioactive compounds, crude extracts, and essential oils have demonstrated potent antioxidant, antimicrobial, anti-inflammatory, antiviral properties, particularly in vitro or silico; however, their vivo applications are hindered by inadequate absorption distribution the organism. The incorporation of these phytochemicals into solid lipid nanoparticles (SLN) nanostructured carriers (NLC) has significant advancements represents a viable approach to improve bioavailability through different administration routes.

Language: Английский

Citations

1
Soothing the Itch: The Role of Medicinal Plants in Alleviating Pruritus in Palliative Care DOI Creative Commons
Sara Gonçalves, Lisete Fernandes, Ana Caramelo

et al.

Plants, Journal Year: 2024, Volume and Issue: 13(24), P. 3515 - 3515

Published: Dec. 16, 2024

Chronic pruritus, or persistent itching, is a debilitating condition that severely impacts quality of life, especially in palliative care settings. Traditional treatments often fail to provide adequate relief are associated with significant side effects, prompting interest alternative therapies. This review investigates the antipruritic potential eight medicinal plants: chamomile (Matricaria chamomilla), aloe vera (Aloe barbadensis), calendula (Calendula officinalis), curcumin (Curcuma longa), lavender (Lavandula angustifolia), licorice (Glycyrrhiza glabra), peppermint (Mentha piperita), and evening primrose (Oenothera biennis). These plants analyzed for their traditional applications, active bioactive compounds, mechanisms action, clinical evidence, usage, dosage, safety profiles. Comprehensive searches were conducted databases including PubMed, Web Science, Scopus, b-on, focusing on vitro, animal, studies using keywords like “plant”, “extract”, “pruritus”. Studies included regardless publication date limited English-language articles. Findings indicate compounds such as polysaccharides vera, curcuminoids turmeric, menthol exhibit anti-inflammatory, antioxidant, immune-modulating properties. Chamomile alleviate itching through anti-inflammatory skin-soothing while offer antimicrobial benefits alongside relief. Evening primrose, rich gamma-linolenic acid, effective atopic dermatitis-related itching. Despite promising preclinical results, challenges remain standardizing dosages formulations. The highlights necessity further trials ensure efficacy safety, advocating integrating these botanical therapies into complementary practices. Such approaches emphasize holistic treatment, addressing chronic pruritus’s physical emotional burden, thereby enhancing patient well-being.

Language: Английский

Citations

1
Antibacterial effects of thyme oil loaded solid lipid and chitosan nano-carriers against Salmonella Typhimurium and Escherichia coli as food preservatives DOI Creative Commons

Amirhosein Shabgoo Monsef,

Mehran Nemattalab, Shirin Parvinroo

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(12), P. e0315543 - e0315543

Published: Dec. 31, 2024

Objectives Escherichia coli and Salmonella Typhimurium are frequent causes of foodborne illness affecting many people annually. In order to develop natural antimicrobial agents against these microorganisms, thyme oil (TO) was considered as active antibacterial ingredient. TO contains various bioactive compounds that exhibit properties. To increase the effects stability oil, two promising carrier systems, solid lipid nanoparticles (SLN) chitosan have been fabricated in this study. Methods Nanoparticles were made using natural-based lipids polymers by a probe sonication method. They characterized infrared spectrometry (FTIR), transmission electron microscopy (TEM), particle size, cytotoxicity, etc. Antibacterial TO, loaded SLN (TO-SLN) nanoparticle (TO-CH) evaluated E . S typhimurium Minimum inhibitory/bactericidal concentrations (MIC/MBC) determination. Encapsulation efficiency (EE%) drug release profile also studied vitro Results TEM analysis revealed spherical/ovoid-shaped particles with clear edges. TO-SLN had an average size 42.47nm, while TO-CH 144.8nm. The TO–CH TO–SLN about 81.6±1% 73.4±1%, respectively. indicated 92% cumulative comparison 88% 72 h. MIC for TO-CH, TO-SLN, pure 4 1.5 μg/mL, 60 40 180–150 Conclusion Nanoencapsulation significantly potentiated its effects. exhibited higher effect compared (6-fold) (more than 10-fold).

Language: Английский

Citations

1
Potential advancement utilizing nanotechnology-based delivery system to enhance the therapeutic properties of lavender essential oil: a review article DOI Creative Commons

A.M. Bagas Trianloka,

Lutfi Chabib,

Arba Pramundita Ramadani

et al.

Jurnal Ilmiah Farmasi (Scientific Journal of Pharmacy), Journal Year: 2024, Volume and Issue: 20(2), P. 231 - 243

Published: Dec. 31, 2024

Background: Essential oils (EO), such as lavender (Lavandula spp.), which are derived from its flower, have become a growing trend in recent years an alternative medicine therapy. However, the poor physicochemical properties of EOs several disadvantages for their application. Integrating nanotechnology into formulation medicinal dosage forms may provide viable way to mitigate these limitations and improve effectiveness EO utilization.Objective: This literature review aims gather information on benefits prospective applications nanotechnology-based delivery systems EOs.Method: Online databases PubMed, Science Direct, Research Gate, Google Scholar, other reliable sources were used find 65 publications between 1991 2021, assessed this review.Results: It is revealed that main constituents linalool, linalyl acetate, lavandulyl acetate. Its antibacterial, antioxidant, anticancer, anti-anxiety, having effects central nervous system, along with qualities including pain relief, has been demonstrated via numerous studies. Additionally, it was dermatological helped treat dermatitis encouraged both hair growth wound healing. Furthermore, also found application improved concentration active compounds blood produced stable form while increasing efficacy.Conclusion: feasible create nanoparticle can substance's solubility, stability, pharmacological effects. More research necessary formulate by applying nanotechnology.

Language: Английский

Citations

0