Molecular Evolution of the Major Arthropod Chemoreceptor Gene Families

Annual Review of Entomology, Journal Year: 2018, Volume and Issue: 64(1), P. 227 - 242

Published: Oct. 12, 2018

The evolutionary origins of the three major families chemoreceptors in arthropods-the odorant receptor (OR), gustatory (GR), and ionotropic (IR) families-occurred at base Insecta, Animalia, Protostomia, respectively. Comparison family sizes across arthropods reveals a generally positive correlation with their widely disparate complexity chemical ecology. Closely related species reveal ongoing processes gene evolution, including duplication, divergence, pseudogenization, loss, that mediate these larger patterns. Sets paralogous receptors within selection on amino acids regions likely to contribute ligand binding specificity. Ligands many ORs some GRs IRs have been identified; however, identification for more is needed, as are structures OR/GR superfamily, improve our understanding molecular evolution ecologically important arthropods.

Language: Английский

---

Chemical Ecology, Biochemistry, and Molecular Biology of Insect Hydrocarbons

Annual Review of Entomology, Journal Year: 2021, Volume and Issue: 66(1), P. 45 - 60

Published: Jan. 7, 2021

Insect cuticular hydrocarbons (CHCs) consist of complex mixtures straight-chain alkanes and alkenes, methyl-branched hydrocarbons. In addition to restricting water loss through the cuticle preventing desiccation, they have secondarily evolved serve a variety functions in chemical communication play critical roles as signals mediating life histories insects. this review, we describe physical properties CHCs that allow for both waterproofing signaling functions, summarize their inter- intraspecific signals, discuss influences diet environment on CHC profiles. We also present advances our understanding hydrocarbon biosynthesis. Hydrocarbons are biosynthesized oenocytes transported by lipophorin proteins. Recent work synthesis fatty acids ultimate reductive decarbonylation has taken advantage powerful new tools molecular biology, including genomics RNA interference knockdown specific genes, provide insights into biosynthesis

Language: Английский

---

Drosophilasensory receptors—a set of molecular Swiss Army Knives

Genetics, Journal Year: 2021, Volume and Issue: 217(1), P. 1 - 34

Published: Jan. 1, 2021

Genetic approaches in the fruit fly, Drosophila melanogaster, have led to a major triumph field of sensory biology-the discovery multiple large families receptors and channels. Some these families, such as transient receptor potential channels, are conserved from animals ranging worms humans, while others, "gustatory receptors," "olfactory "ionotropic restricted invertebrates. Prior identification flies, it was widely assumed that proteins function just one modality vision, smell, taste, hearing, somatosensation, which includes thermosensation, light, noxious mechanical touch. By employing vast combination genetic, behavioral, electrophysiological, other concept emerge is many multitaskers. The earliest example this idea individual channels senses. It now clear multitasking exhibited by including gustatory receptors, ionotropic epithelial Na+ (also referred Pickpockets), even opsins, were formerly thought exclusively light sensors. characterizations neurons express them also reveal mechanisms through flies can accurately differentiate between different stimuli when they activate same receptor, well adaptation, amplification, integration. insights gleaned studies been highly influential directing investigations animal models.

Language: Английский

---

Chemical Cues that Guide Female Reproduction in Drosophila melanogaster

Journal of Chemical Ecology, Journal Year: 2018, Volume and Issue: 44(9), P. 750 - 769

Published: March 19, 2018

Language: Английский

---

Insect Pheromone Receptors – Key Elements in Sensing Intraspecific Chemical Signals

Frontiers in Cellular Neuroscience, Journal Year: 2018, Volume and Issue: 12

Published: Nov. 20, 2018

Pheromones are chemicals that serve intraspecific communication. In animals, the ability to detect and discriminate pheromones in a complex chemical environment substantially contributes survival of species. Insects widely use attract mating partners, alarm conspecifics or mark paths rich food sources. The various functional roles for insects is reflected by diversity pheromonal compounds. precise detection relevant signals accomplished specialized chemosensory neurons housed hair-like sensilla located on surface body appendages. Current data indicate extraordinary sensitivity selectivity pheromone-responsive (PRNs) largely based specific pheromone receptors (PRs) residing their ciliary membrane. Besides these key elements, proper ligand-induced responses PR-expressing appear generally require putative co-receptor, so-called "sensory neuron membrane protein 1" (SNMP1). Regarding PR-mediated chemo-electrical signal transduction processes insect PRNs, ionotropic as well metabotropic mechanisms may be involved. this review, we summarize discuss current knowledge peripheral olfactory system with focus PRs role recognition volatile signals.

Language: Английский

---

Large-scale characterization of sex pheromone communication systems in Drosophila

Nature Communications, Journal Year: 2021, Volume and Issue: 12(1)

Published: July 6, 2021

Abstract Insects use sex pheromones as a reproductive isolating mechanism to attract conspecifics and repel heterospecifics. Despite the profound knowledge of pheromones, little is known about coevolutionary mechanisms constraints on their production detection. Using whole-genome sequences infer kinship among 99 drosophilids, we investigate how phylogenetic chemical traits have interacted at wide evolutionary timescale. Through series syntheses electrophysiological recordings, identify 52 sex-specific compounds, many which are detected via olfaction. Behavioral analyses reveal that 43 male-specific compounds transferred female during copulation mediate receptivity and/or male courtship inhibition. Measurement signals demonstrates cognate olfactory channels evolve rapidly independently over time guarantee efficient intra- inter-specific communication systems. Our results show sexual isolation barriers between species can be reinforced by species-specific signals.

Language: Английский

---

Tephritid Fruit Fly Semiochemicals: Current Knowledge and Future Perspectives

Insects, Journal Year: 2021, Volume and Issue: 12(5), P. 408 - 408

Published: April 30, 2021

The Dipteran family Tephritidae (true fruit flies) comprises more than 5000 species classified in 500 genera distributed worldwide. include devastating agricultural pests and highly invasive whose spread is currently facilitated by globalization, international trade human mobility. ability to identify exploit a wide range of host plants for oviposition, as well effective diversified reproductive strategies, are among the key features supporting tephritid biological success. Intraspecific communication involves exchange complex set sensory cues that species- sex-specific. Chemical signals, which standing out communication, comprise long-distance pheromones emitted one or both sexes, cuticular hydrocarbons with limited volatility deposited on surrounding substrate insect body regulating medium- short-distance host-marking compounds after oviposition. In this review, current knowledge chemical was analysed special emphasis fly pest belonging Anastrepha, Bactrocera, Ceratitis, Rhagoletis Zeugodacus genera. multidisciplinary approaches adopted characterising semiochemicals, real-world applications challenges Integrated Pest Management (IPM) control strategies critically discussed. Future perspectives targeted research highlighted.

Language: Английский

---

A volatile sex attractant of tsetse flies

Science, Journal Year: 2023, Volume and Issue: 379(6633)

Published: Feb. 16, 2023

Tsetse flies transmit trypanosomes-parasites that cause devastating diseases in humans and livestock-across much of sub-Saharan Africa. Chemical communication through volatile pheromones is common among insects; however, it remains unknown if how such chemical occurs tsetse flies. We identified methyl palmitoleate (MPO), oleate, palmitate as compounds are produced by the fly

Language: Английский

---

Aggregation pheromones have a non-linear effect on oviposition behavior in Drosophila melanogaster

Nature Communications, Journal Year: 2023, Volume and Issue: 14(1)

Published: March 20, 2023

Female fruit flies (Drosophila melanogaster) oviposit at communal sites where the larvae may cooperate or compete for resources depending on group size. This offers a model system to determine how females assess quantitative social information. We show that concentration of pheromones found substrate increases linearly with number adult have visited site. Females prefer oviposition pheromone concentrations corresponding an intermediate previous visitors, whereas low high are unattractive. dose-dependent decision is based blend 11-cis-Vaccenyl Acetate (cVA) indicating visitors and heptanal (a novel deriving from oxidation 7-Tricosene), which acts as dose-independent co-factor. response mediated by detection cVA odorant receptor neurons Or67d Or65a, least five different heptanal. Our results identify mechanism allowing individuals transform linear increase into non-linear behavioral response.

Language: Английский

---

In the mood for sex: neural circuits for reproduction

Current Opinion in Neurobiology, Journal Year: 2019, Volume and Issue: 60, P. 155 - 168

Published: Dec. 31, 2019

Language: Английский

---