Cardiovascular Diabetology,
Journal Year:
2024,
Volume and Issue:
23(1)
Published: Aug. 31, 2024
The
association
between
baseline
triglyceride
glucose
index
(TyG
index)
and
incident
non-communicable
diseases,
mainly
in
Asian
populations,
has
been
reported.
In
the
current
study,
we
aimed
to
evaluate
index-year,
average,
visit-to-visit
variability
(VVV)
of
TyG
with
type
2
diabetes
mellitus
(T2DM),
hypertension,
cardiovascular
disease
(CVD),
all-cause
mortality
among
Iranian
population.
Frontiers in Endocrinology,
Journal Year:
2024,
Volume and Issue:
15
Published: July 11, 2024
Background
Globally,
gallstones
represented
a
prevalent
condition
of
the
digestive
system,
heavily
affected
by
metabolic
dysfunctions
such
as
obesity,
dyslipidemia,
insulin
resistance,
and
diabetes.
The
triglyceride-glucose
(TyG)
index
served
an
accessible
novel
indicator
for
evaluating
offering
precise
reflection
conditions.
However,
no
studies
have
yet
explored
their
relationship.
link
between
TyG
gallstone
risk
was
primary
purpose
this
study.
Methods
Utilized
data
from
public
database,
National
Health
Nutrition
Examination
Survey,
years
2017-2020.
logit
model
utilized
to
elucidate
connection
risk.
restricted
cubic
spline
(RCS)
analysis
verify
any
non-linear
relationships
existing
them.
Sensitivity
analyses,
encompassing
both
stratified
interaction
were
conducted
identify
populations
particular
interest
assess
potential
interactions
covariates
index.
Results
A
total
4544
individuals
included.
in
high
group
1.6
times
that
low
group.
cut-off
value
6.19.
Above
threshold,
there
40%
heightened
with
each
one-unit
increment
TyG.
RCS
revealed
absence
association
warranting
focus
included
those
over
60
years,
non-White
people,
body
mass
≥25,
smokers,
drinkers,
hypertension,
Apart
smoking
history,
alcohol
consumption,
history
diabetes,
other
variables
Conclusion
current
study
inaugural
investigation
into
gallstones.
positive
correlation
existed
them,
signifying
increase
paralleled
elevated
No
relationship
has
been
found
Besides,
accompanied
unit
rise
Considering
convenience
accessibility
clinical
settings,
it
promising
application.
Abstract
Background
The
association
between
the
triglyceride-glucose
(TyG)
index
and
clinical
outcomes
in
patients
with
both
coronary
artery
disease
(CAD)
psoriasis
is
unclear.
This
study
investigated
TyG
major
adverse
cardiovascular
events
(MACE)
CAD
psoriasis.
Methods
retrospective
cohort
included
diagnosed
who
underwent
angiography
at
Fuwai
Hospital,
Beijing,
China,
January
2017
May
2022.
endpoint
was
occurrence
of
MACE
or
end
follow-up
time.
Multivariate
Cox
proportional
analysis
restricted
cubic
splines
(RCS)
were
used
to
determine
MACE.
Receiver
operating
characteristic
(ROC)
curves
optimal
threshold
value
for
predicting
Results
enrolled
293
psoriasis,
including
258
(88.1%)
males
a
mean
age
58.89
±
9.61
years.
Patients
divided
into
four
groups
based
on
quartiles:
Q1
(
N
=
74),
Q2
73),
Q3
Q4
73).
After
adjusting
potential
confounders,
independently
associated
MACE,
as
continuous
variable
(HR
1.53,
95%
CI
1.03–2.28,
P
0.035)
categorical
(Q1:
reference;
Q2:
HR
1.85,
0.88–3.87,
0.105;
Q3:
2.39,
1.14-5.00,
0.021;
Q4:
2.19,
1.001–4.81,
0.0497;
trend
0.039).
RCS
showed
an
linear
(P-overall
0.027,
P-non-linear
0.589).
ROC
curve
that
≥
8.73
(area
under
0.60,
0.53–0.67).
significantly
2.10,
1.32–3.34,
0.002).
adjustment
independent
2.00,
1.17–3.42,
0.011).
Conclusions
positive
correlation
might
be
Graphical
Cardiovascular Diabetology,
Journal Year:
2024,
Volume and Issue:
23(1)
Published: Aug. 31, 2024
The
association
between
baseline
triglyceride
glucose
index
(TyG
index)
and
incident
non-communicable
diseases,
mainly
in
Asian
populations,
has
been
reported.
In
the
current
study,
we
aimed
to
evaluate
index-year,
average,
visit-to-visit
variability
(VVV)
of
TyG
with
type
2
diabetes
mellitus
(T2DM),
hypertension,
cardiovascular
disease
(CVD),
all-cause
mortality
among
Iranian
population.
