Nanoscale Research Letters,
Journal Year:
2022,
Volume and Issue:
17(1)
Published: July 26, 2022
Gold
nanorods
(AuNRs)
are
ideal
inorganic
nanophotothermal
agents
with
unique
characteristics,
including
local
surface
plasmon
resonance
effects,
easy
scale
preparation
and
functional
modification,
good
biocompatibility.
This
review
summarizes
several
recent
advances
in
AuNRs-based
photothermal
therapy
(PTT)
research.
Functionalized
AuNRs
have
optimized
biocompatibility
targeting
properties.
The
multifunctional
nanoplatform
composite
structure
meets
the
requirements
for
synergistic
effects
of
PTT,
photoacoustic
imaging,
other
therapeutic
methods.
Photothermal
(AuNRs-PTT)
is
widely
used
to
treat
tumors
inflammatory
diseases;
its
tumor-targeting,
tumor
metastasis
inhibition,
ablation
abilities
remarkable
curative
effects.
An
in-depth
study
living
systems
interactions
between
biological
structure,
nanomaterial,
near-infrared
irradiation
could
lay
foundation
further
clinical
research
broad
application
PTT.
Journal of Biomaterials Science Polymer Edition,
Journal Year:
2022,
Volume and Issue:
33(11), P. 1435 - 1468
Published: March 16, 2022
Skin-cancer
(SC)
is
more
common
than
all
other
cancers
affecting
large
percentage
of
the
population
in
world
and
increasing
terms
morbidity
mortality.
In
United
States,
3million
people
are
affected
by
SC
annually
whereas
millions
globally.
Melanoma
fifth
most
cancer
States.
commonly
occurred
white
as
per
WHO.
divided
into
two
groups,
i.e.
melanoma
non-melanoma.
previous
decades,
management
remains
to
be
a
tough
challenging
task
for
many
scholars.
Presently,
treatment
protocols
mostly
based
on
surgery
chemo-radiation
therapy,
which
sooner
or
later
harm
unaffected
cells
too.
To
reduce
these
limitations,
nano
scaled
materials
its
extensive
range
may
recognized
probable
carriers
selective
drug
delivery
response
cancerous
cells.
Recently,
nanocarriers
drugs
their
combinations
were
found
new
interesting
approach
study
skin
carcinoma
enhance
effectiveness,
lessen
dose-dependent
side
effects
avoid
resistance.
This
review
emphasize
wide-range
information
nanotechnology-based
combination
with
physical
techniques.
ACS Nano,
Journal Year:
2022,
Volume and Issue:
16(5), P. 8472 - 8483
Published: April 25, 2022
Most
cancer-related
deaths
are
due
to
metastasis
or
recurrence.
Therefore,
the
ultimate
goal
of
cancer
therapy
will
be
treat
metastatic
and
recurrent
cancers.
Combination
for
one
trial
effective
treating
In
this
study,
Escherichia
coli-mimetic
nanomaterials
synthesized
using
coli
membrane
proteins,
adhesion
gold
nanorods,
which
named
E.
mimetic
AuNRs
(ECA),
combination
against
its
ECA
treatment
with
808
nm
laser
irradiation
eliminates
CT-26
4T1
tumors
via
a
photothermal
effect.
induces
activation
immune
cells
in
tumor-draining
lymph
nodes.
The
mice
cured
from
tumor
by
rechallenged
those
lung
form,
results
showed
that
first
challenge
prevents
infiltration
second
challenge.
This
preventive
effect
growth
is
aided
antigen-specific
T
cell
immunity.
Overall,
these
findings
show
nanomaterial
dual
functions
as
primary
cancers
immunotherapy
preventing
recurrence
metastasis.
