Impressive strides in antibacterial performance amelioration of Ti-based implants via plasma electrolytic oxidation (PEO): A review of the recent advancements

Chemical Engineering Journal, Journal Year: 2022, Volume and Issue: 441, P. 136003 - 136003

Published: March 26, 2022

Ti and Ti-alloys are widely utilized as suitable biomaterials for implants, since they present good biocompatibility mechanical properties. However, can be an ideal substrate bacteria attachment, promoting biofilm infections. Biomaterial-associated infections is one of the major healthcare challenges that currently faced by humanity. This fact causes increased morbidity distress in patients, along with high economic costs due to hospitalizations. There several strategies overcome infection associated especially plasma electrolytic oxidation (PEO) process. PEO highly effective production hard, porous, wear- corrosion-resistant, well biocompatible coatings. Additionally, this method applied introduce antibacterial coatings, most prevalent ones being bacteria-killing bacteria-repelling. Thus, review, formation implications implants presented, mechanisms presently known. The effect on ability will then discussed detail. Finally, procedure parameters modifications lead performance presented.

Language: Английский

---

Nanomaterial-Based Antimicrobial Coating for Biomedical Implants: New Age Solution for Biofilm-Associated Infections

ACS Omega, Journal Year: 2022, Volume and Issue: 7(50), P. 45962 - 45980

Published: Dec. 10, 2022

Recently, the upsurge in hospital-acquired diseases has put global health at risk. Biomedical implants being primary source of contamination, development biomedical with antimicrobial coatings attracted attention a large group researchers from around globe. Bacteria develops biofilms on surface implants, making it challenging to eradicate them standard approach administering antibiotics. A further issue current concern is fast resurgence resistance conventional As nanotechnology continues advance, various types nanomaterials have been created, including 2D nanoparticles and metal oxide properties. Researchers all over world are using these materials as coating agent for create an environment. This comprehensive contemporary review summarizes metals, nanoparticles, nanomaterials, their composites that used or may be future well succinct mode action combat biofilm-associated infection diseases.

Language: Английский

---

Recent Development of Polyhydroxyalkanoates (PHA)-Based Materials for Antibacterial Applications: A Review

ACS Applied Bio Materials, Journal Year: 2023, Volume and Issue: 6(4), P. 1398 - 1430

Published: March 13, 2023

The diseases caused by microorganisms are innumerable existing on this planet. Nevertheless, increasing antimicrobial resistance has become an urgent global challenge. Thus, in recent decades, bactericidal materials have been considered promising candidates to combat bacterial pathogens. Recently, polyhydroxyalkanoates (PHAs) used as green and biodegradable various alternative applications, especially healthcare for antiviral or purposes. However, it lacks a systematic review of the application emerging material antibacterial applications. Therefore, ultimate goal is provide critical state art development PHA biopolymers terms cutting-edge production technologies well fields. In addition, special attention was given collecting scientific information agents that can potentially be incorporated into biological durable protection. Furthermore, current research gaps declared, future perspectives proposed better understand properties these their possible

Language: Английский

---

Synthesis and Antimicrobial Applications of ZnO Nanostructures: A Review

ACS Applied Nano Materials, Journal Year: 2023, Volume and Issue: 6(13), P. 10881 - 10902

Published: June 21, 2023

ZnO nanostructures (ZnO NSs) are able to provide significant antimicrobial activity, ensuring high biocompatibility, good chemical stability, and low toxicity. Such versatility has led great success of this nanomaterial for antibacterial, antifungal, and, more recently, antiviral applications. However, methods the preparation NSs must be properly selected their end use. Moreover, can also cytotoxic some extent. In context, review emphasizes aspects relevant as well use NSs. particular, a brief overview sol–gel, hydrothermal, biogenic, electrochemical approaches proposed synthesis is presented, highlighting advantages/drawbacks each route in terms scalability, simplicity, efficacy. Next, application several fields reported. This followed by discussion role NSs, where mechanisms action, possible cell resistance, cytotoxicity highlighted. We discuss against different biothreats, such bacteria viruses. The future nanomaterials field addressed final part.

Language: Английский

---

Metal-Based Nanoparticles as Antimicrobial Agents: A Review

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: 7(3), P. 2529 - 2545

Published: Jan. 18, 2024

Antibiotic abuse has become a rising public health concern in recent years, leading to dangerous bacteria developing antibiotic resistance most medicines currently use. Traditional antimicrobial medications have been helpful the early stages of treating numerous forms serious bacterial infectious diseases; however, despite significant therapeutic benefit, there are number issues with follow-up treatment. Metal-based nanomaterials, which properties including difficulty establishing drug and advantages reduced cytotoxicity, considered promising substances. This review discusses important types metal-based nanoparticles (MNPs), such as copper, titanium, zinc oxide, etc., focus on applications gold- silver-based nanoparticles. Furthermore, advanced research progress MNPs agents stimuli-responsive metal nanoparticle strategies working under photothermal, magnetic, pH stimulation also summarized this article. In general, advancement technology, materials based will offer excellent prospects for improving applications.

Language: Английский

---

The impact of biocorrosion and titanium ions release on peri-implantitis

Clinical Oral Investigations, Journal Year: 2025, Volume and Issue: 29(3)

Published: Feb. 25, 2025

Language: Английский

---

Cell membrane-camouflaged inorganic nanoparticles for cancer therapy

Journal of Nanobiotechnology, Journal Year: 2022, Volume and Issue: 20(1)

Published: June 18, 2022

Inorganic nanoparticles (INPs) have been paid great attention in the field of oncology recent past years since they enormous potential drug delivery, gene photodynamic therapy (PDT), photothermal (PTT), bio-imaging, driven motion, etc. To overcome innate limitations conventional INPs, such as fast elimination by immune system, low accumulation tumor sites, and severe toxicity to organism, efforts recently made modify naked facilitating their clinical application. Taking inspiration from nature, considerable researchers exploited cell membrane-camouflaged INPs (CMCINPs) coating various membranes onto INPs. CMCINPs naturally inherit surface adhesive molecules, receptors, functional proteins original membrane, making them versatile natural cells. In order give a timely representative review on this rapidly developing research subject, we highlighted advances with superior unique merits for cancer applications. The opportunity obstacles translation were also discussed. is expected assist better eliciting effect management tumors may catalyze breakthroughs area.

Language: Английский

---

Polymeric Dental Nanomaterials: Antimicrobial Action

Polymers, Journal Year: 2022, Volume and Issue: 14(5), P. 864 - 864

Published: Feb. 22, 2022

This review aims to describe and critically analyze studies published over the past four years on application of polymeric dental nanomaterials as antimicrobial materials in various fields dentistry. Nanoparticles are promising additives restoration materials. According data, composites based silver nanoparticles, zinc(II), titanium(IV), magnesium(II), copper(II) oxide chitosan calcium phosphate or fluoride nanodiamonds can be used therapy endodontics. Composites with nanoparticles hydroxyapatite bioactive glass proved low efficiency for these fields. The applicable orthodontics include nanodiamonds, titanium(IV) zinc(II) glass, yttrium(III) nanoparticles. periodontics, silver, chitosan, employed implantology prosthetics. also utilized maxillofacial surgery manufacture prostheses. halloysite nanotubes field denture calcium(II) therapeutic dentistry tooth restoration.

Language: Английский

---

Fucoidan-derived carbon dots against Enterococcus faecalis biofilm and infected dentinal tubules for the treatment of persistent endodontic infections

Journal of Nanobiotechnology, Journal Year: 2022, Volume and Issue: 20(1)

Published: July 14, 2022

Enterococcus faecalis (E. faecalis) biofilm-associated persistent endodontic infections (PEIs) are one of the most common tooth lesions, causing chronic periapical periodontitis, root resorption, and even loss. Clinical canal disinfectants have risk damaging soft tissues (e.g., mucosa tongue) teeth in oral cavity, unsatisfactory to therapy PEIs. Nanomaterials with remarkable antibacterial properties good biocompatibility been developed as a promising strategy for removing pathogenic bacteria related biofilm. Herein, carbon dots (CDs) derived from fucoidan (FD) prepared through one-pot hydrothermal method treatment The FDCDs (7.15 nm) sulfate groups fluorescence property well dispersed stable water. Further, it is found that vitro display excellent inhibiting effects on E. its biofilm by inducing formation intracellular extracellular reactive oxygen species altering bacterial permeability. Importantly, penetrated canals dentinal tubules, located Moreover, cellular assays show satisfactory cytocompatibility promote macrophage recruitment. Thus, hold great potential management

Language: Английский

---

Advances in sustainable grinding of different types of the titanium biomaterials for medical applications: A review

Biomedical Engineering Advances, Journal Year: 2022, Volume and Issue: 4, P. 100047 - 100047

Published: July 22, 2022

This review discusses various grades of titanium biomaterials and their sustainable grindability for application in the medical field. Titanium are most commonly utilized applications due to exceptional characteristics such as high corrosion resistance biocompatibility. The presented looks at principal requirements applications, some good mechanical properties, biocompatibility, corrosion, wear processability that facilitate successful implantation implants. It types alloys commercially available and, more specifically, used applications. highlights properties different further narrows down its primary focus on advantages, shortcomings biomaterials. Machining is a difficult task inherent low thermal conductivity chemical reactivity temperatures usually results changes metallurgy surface integrity machined surface. Conventional machining, which has been main machining method, limitations related environmental hazards, cutting fluid costs, operator health issues have necessitated development machining. emphasis this placed grinding techniques MQL cryogenic nano-particle high-pressure solid lubrication grind benefits limitations. Finally, will highlight potential areas future research trends cooling methods believed be great benefit industries involved manufacturing titanium-based

Language: Английский

---