Vaccine, Journal Year: 2024, Volume and Issue: 42(11), P. 2877 - 2885
Published: March 22, 2024
Previous studies have reported high COVID-19 vaccine hesitancy among people who inject drugs. We aimed to examine coverage, motivations and barriers vaccination, factors associated with uptake this population in Australia, 1.5 years after rollout commenced.
Language: Английский
Vaccine, Journal Year: 2023, Volume and Issue: 41(12), P. 1916 - 1924
Published: Jan. 23, 2023
We studied characteristics of COVID-19 vaccination uptake among people who inject drugs (PWID). Participants aged ≥18 years injected ≤1 month ago were recruited into a community-based cohort from October 2020 to September 2021 in San Diego, California Poisson regression identified correlates having had ≥1 vaccine dose based on semi-annual follow-up interviews through March 15, 2022. Of 360 participants, 74.7% male, mean age was 42 years; 63.1% Hispanic/Mexican/Latinx. More than one-third co-morbidity. HIV and HCV seroprevalence 4.2% 50.6% respectively; 41.1% lacked health insurance. Only 37.8% reported dose. None received ≥3 doses. However, those vaccinated, 37.5% previously unwilling/unsure about vaccines. Believing vaccines include tracking devices (adjusted incidence rate ratio [aIRR]: 0.62; 95% CI: 0.42,0.92) lacking insurance (aIRR: 0.60; 0.40,0.91) associated with approximately 40% lower rates). Ever receiving influenza 2.16; 95%CI: 1.46, 3.20) testing HIV-seropositive 2.51; 1.03, 6.10) or SARS-CoV-2 RNA-positive 1.82; 1.05, 3.16) independently predicted higher rates. Older age, knowing more vaccinated people, recent incarceration also One year after became available U.S. adults, only one third PWID Multi-faceted approaches that dispel disinformation, integrate public social services increase access free, are urgently needed.
Language: Английский
Citations
22
Harm Reduction Journal, Journal Year: 2023, Volume and Issue: 20(1)
Published: July 29, 2023
Abstract Background People Who Use Drugs (PWUD) have lower vaccination uptake than the general population, and disproportionately experience burden of harms from vaccine-preventable diseases. We conducted a national qualitative study to: (1) identify barriers facilitators to receiving COVID-19 vaccinations among PWUD; (2) interventions support PWUD in their decision-making. Methods Between March October 2022, semi-structured interviews with across Canada were conducted. Fully vaccinated (2 or more doses) partially unvaccinated (1 dose less) participants recruited convenience sample participate telephone discuss facilitators, barriers, concerns about vaccines subsequent boosters, ways address concerns. A total 78 participated study, 50 being fully 28 unvaccinated. Using thematic analysis, coded based on capability, opportunity, motivation-behavior (COM-B) framework. Results Many reported lacking knowledge vaccine, particularly terms its usefulness benefits. Some around potential long-term side effects differences various vaccine brands. Distrust toward government healthcare agencies, unprecedented rapidity development skepticism effectiveness also noted as barriers. Facilitators for included desire protect oneself others compliance mandates which required individuals get order access services, attend work travel. To improve uptake, most trusted appropriate avenues information sharing identified by be people lived living drug use (PWLLE), harm reduction workers, providers working within settings commonly visited PWUD. Conclusion PWLLE should supported design tailored reduce mistrust. Resources addressing gaps disseminated areas through organizations where frequently access, such services social media platforms.
Language: Английский
Citations
10
International Journal of Drug Policy, Journal Year: 2024, Volume and Issue: 127, P. 104382 - 104382
Published: March 19, 2024
People who inject drugs may be at excess risk of acquiring vaccine-preventable diseases and negative associated health outcomes, but experience barriers to vaccination. We aimed determine vaccination coverage among people globally. conducted systematic searches the peer-reviewed grey literature, date limited from January 2008 August 2023, focusing on for which are elevated an adult dose is recommended (COVID-19, hepatitis A, B, human papillomavirus, influenza, pneumococcal disease, tetanus). To summarise available data, we a narrative synthesis. included 78 studies/reports comprising 117 estimates across 36 countries. Most were obtained high income countries (80%, n=94). located B in 33 countries, 18 with data serological evidence vaccine-derived immunity (range: 6-53%) 22 self-report vaccine uptake (<1-96%). Data other vaccines scarcer: reported A ranged 3-89% (five countries), COVID-19 4-84% while fewer than five tetanus, papillomavirus. Estimates sparse where indicative suboptimal drugs. Improving consistency, timeliness, geographic this population essential inform efforts increase uptake.
Language: Английский
Citations
3
Harm Reduction Journal, Journal Year: 2023, Volume and Issue: 20(1)
Published: March 28, 2023
Abstract Background A precipitous decline in health status among people recently released from prison is common. In Victoria, Australia, opioid agonist treatment (OAT) the community involves frequent contact with primary care, potentially facilitating broader use of healthcare services. Among a cohort men who injected drugs regularly pre-imprisonment, we estimated differences rates and medication dispensation between did not receive OAT post-release. Methods Data came Prison Transition Health Cohort Study. Three-month post-release follow-up interviews were linked care records. Generalised linear models fit one exposure (OAT: none/partial/complete) for 13 outcomes relating to use, pathology testing, dispensation, adjusted other covariates. Coefficients reported as incidence rate ratios (AIRR). Results Analyses included 255 participants. Compared no both partial complete associated increased standard (AIRR: 3.02, 95%CI: 1.88–4.86; AIRR: 3.66, 2.57–5.23), extended 2.56, 1.41–4.67; 2.55, 1.60–4.07) mental health-related 2.71, 1.42–5.20; 2.27, 1.33–3.87) general practitioner (GP) consultations, total 1.88, 1.19–2.98; 2.40, 1.71–3.37), benzodiazepine 4.99, 2.81–8.85; 8.30, 5.28–13.04) gabapentinoid 6.78, 3.34–13.77; 4.34, 2.37–7.94) dispensations, respectively. Partial was also after-hours GP consultations 4.61, 2.24–9.48) use? utilisation (e.g. haematological, chemical, microbiological or immunological tissue/sample testing; 2.30, 1.52–3.48). Conclusion We observed higher Findings suggest that access may have collateral benefit supporting service utilisation, underscoring importance retention after release prison.
Language: Английский
Citations
6
Harm Reduction Journal, Journal Year: 2023, Volume and Issue: 20(1)
Published: May 3, 2023
Abstract Background To examine COVID-19 vaccination and HIV transmission among persons who inject drugs (PWID) during the pandemic (2020–2022) in New York City (NYC). Methods Two hundred seventy five PWID were recruited from October 2021 to September 2022. A structured questionnaire was used measure demographics, drug use behaviors, overdose experiences, substance treatment history, infection, vaccination, attitudes. Serum samples collected for HIV, HCV, SARS-CoV-2 (COVID-19) antibody testing. Results Participants were: 71% male, mean age 49 (SD 11), 81% reported at least one immunization, 76% fully vaccinated 64% of unvaccinated had antibodies COVID-19. Self-reported injection risk behaviors very low. seroprevalence 7%. Eighty-nine percent seropositive respondents knowing they being on antiretroviral therapy prior pandemic. There two likely seroconversions 518.83 person-years March 2020 start times interviews, an estimated incidence rate 0.39/100 person-years, 95% Poisson CI 0.05–1.39/100 person-years. Conclusions is concern that disruptions prevention services psychological stress may lead increased behavior transmission. These data indicate adaptive/resilient both obtaining maintaining a low this sample first years NYC.
Language: Английский
Citations
5
Communications Medicine, Journal Year: 2023, Volume and Issue: 3(1)
Published: May 12, 2023
Abstract Background COVID-19 has hindered hepatitis C virus (HCV) and HIV screening, particularly in marginalised groups, who have some of the highest rates these conditions lowest vaccination. We assessed acceptability combining HCV testing with vaccination a centre for addiction services (CAS) Barcelona mobile unit (MTU) Madrid, Spain. Methods From 28/09/2021 to 30/06/2022, 187 adults from populations were offered antibody (Ab) along If Ab+, they tested HCV-RNA. MTU participants also screened HIV. HCV-RNA+ HIV+ treatment. Data analysed descriptively. Results Findings show how 86 CAS participants: 80 (93%) had been previously vaccinated COVID-19, whom 72 (90%) full first round schedule; none vaccine booster all received COVID - 19 vaccine; 54 (62.8%) Ab, 17 (31.5%) positive, HCV-RNA positive. Of 101 Ab 15 (14.9%) 9 (8.9%) respectively; those (60%) HCV-RNA+, 8 (88.9%) started treatment; 5 (55.6%) abandoned antiretroviral therapy, 3 re-started it. Conclusions The intervention was accepted by can be used communities.
Language: Английский
Citations
5
Open Forum Infectious Diseases, Journal Year: 2023, Volume and Issue: 10(8)
Published: July 21, 2023
We evaluated the impact of a brief peer-led intervention on COVID-19 vaccination among people who inject drugs (PWID) presenting at syringe services program (SSP) locations in San Diego County, California. Between March and July 2022, PWID aged ≥18 years without recent voluntary testing were not up to date vaccinations received single-session motivational interviewing (LinkUP) or an attention-matched didactic control condition from trained peer counselors SSP sites randomized by week. Following either 30-minute session, offered referrals local services. Multivariable log binomial regression via generalized estimating equations assessed LinkUP effects (1) acceptance immediately postintervention (2) vaccine uptake 6-month follow-up. outcomes obtained 135 (90.6%) 149 participants. In multivariable analysis, participants receiving had greater than controls (adjusted relative risk, 3.50; 95% CI, 1.01-12.2) marginally more likely report new dose 1.57; .99-2.48). After 6 months, 20% reported dose; however, if been available SSPs, this proportion could have as high 34.3% (45.3% vs 24.3% control; P = .01). A SSP-based significantly improved PWID. Further improvements be supporting SSPs offer on-site instead relying referrals. ClinicalTrials.gov NCT05181657.
Language: Английский
Citations
4
Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)
Published: Nov. 23, 2023
People with HIV (PWH) are at increased risk of COVID-19 infection. Both Canadian (NACI) and US (CDC) guidelines recommend that all PWH receive least 2 doses vaccine, a booster. We examined vaccination uptake among in Southern Alberta, Canada. Among adult PWH, we evaluated between December 2020 August 2022. Poisson regression models robust variance (approximating log binomial models) estimated crude adjusted prevalence ratios (aPR) 95% confidence intervals (CI) for receiving (1) any vs. no (2) primary series booster (≥ 3 vaccines) versus without 1885 10% received vaccinations, 37% < vaccines 54% ≥ vaccines. Females (vs. males) were less likely to vaccine Receiving was associated White ethnicity, unsuppressed viral load (> 200 copies/mL), using illegal substances. Factors decreased included being younger, Black White) substance use, lower educational attainment, having an load. does not meet guidelines, receipt is unevenly distributed. Booster lowest young females marginalized individuals. Focused outreach necessary close this gap.
Language: Английский
Citations
4
Vaccine, Journal Year: 2024, Volume and Issue: 42(4), P. 864 - 870
Published: Jan. 14, 2024
Language: Английский
Citations
1
AIDS Care, Journal Year: 2024, Volume and Issue: 36(sup1), P. 145 - 153
Published: Jan. 30, 2024
Studies conducted early in the COVID-19 pandemic - before vaccines were widely available indicated that drug use may have declined among sexual minority men (SMM). This study evaluated trends second year of pandemic. Cross-sectional responses from cisgender SMM living US and recruited online (n = 15,897) grouped for analyses: Time 1: 3/1/2021-5/30/2021; 2: 6/1/2021-8/31/2021; 3: 9/1/2021-11/30/2021; 4: 12/1 2021-2/28/2022. Results multivariable models illicit (excluding cannabis) increased at Times 2 (OR 1.249, p < .001), 3 1.668, 4 1.674, .001) compared to 1. In contrast, cannabis was relatively stable over time. Rates did not differ significantly 1, 2, 4. While rates vaccination time, negatively associated with odds 0.361, .001). These findings highlight need ongoing attention risks poses SMM. Illicit a long-standing health disparity across Because they are less likely be vaccinated, who drugs greater risk infection or complications.
Language: Английский
Citations
1