Neuroscience Insights,
Journal Year:
2023,
Volume and Issue:
18
Published: Jan. 1, 2023
Initially,
Severe
Acute
Respiratory
Syndrome
Coronavirus
2
(SARS-CoV-2),
the
virus
responsible
for
coronavirus
disease-2019
(COVID-19),
was
predominantly
considered
to
primarily
affect
respiratory
system.
However,
later
studies
revealed
that
it
also
affects
brain
function
through
its
ability
bind
angiotensin-converting
enzyme
type
(ACE2)
receptors
expressed
on
neural
cells.
Our
study
involved
a
comprehensive
review
of
literature
aiming
investigate
relationship
between
COVID-19
and
development
depression.
analysis
shows
connection
these
conditions,
as
consequence
inflammatory
response
in
nervous
system
psychophysiological
effects
pandemic.
In
patients,
depression
can
arise
either
due
direct
viral
infection
or
result
an
indirect
immune
triggering
neuroinflammation
after
cytokine
storm.
The
resulting
be
treated
with
non-pharmacological
therapies
such
psychotherapy,
antidepressant
medications,
combination
treatments
depending
severity
symptoms.
Frontiers in Public Health,
Journal Year:
2021,
Volume and Issue:
9
Published: Oct. 29, 2021
In
the
current
period
of
global
public
health
crisis
due
to
COVID-19,
healthcare
workers
are
more
exposed
physical
and
mental
exhaustion
–
burnout
for
torment
difficult
decisions,
pain
losing
patients
colleagues,
risk
infection,
themselves
their
families.
The
very
high
number
cases
deaths,
probable
future
“waves”
raise
awareness
these
challenging
working
conditions
need
address
by
identifying
possible
solutions.
Measures
have
been
suggested
prevent
or
reduce
at
individual
level
(physical
activity,
balanced
diet,
good
sleep
hygiene,
family
support,
meaningful
relationships,
reflective
practices
small
group
discussions),
organizational
(blame-free
environments
sharing
experiences
advices,
broad
involvement
in
management
multi-disciplinary
psychosocial
support
teams,
safe
areas
withdraw
quickly
from
stressful
situations,
adequate
time
planning,
social
support),
cultural
(involvement
development,
implementation,
testing,
evaluation
measures
against
burnout).
Although
some
progress
has
made
removing
barrier
psychological
cope
with
work-related
stress,
a
change
is
still
needed
stigma
associated
illness.
key
recommendation
challenges
that
emergency
poses
aggregate
health,
well-being
behavioral
science
expertise
through
long
term
researches
rigorous
planning
reporting
drive
necessary
improvement
systems.
European Psychiatry,
Journal Year:
2022,
Volume and Issue:
65(1)
Published: Jan. 1, 2022
Healthcare
workers
(HCWs)
exposed
to
coronavirus
19
(COVID-19)
are
at
high
risk
of
developing
mental
health
concerns
across
several
domains.
The
aim
this
study
is
determine
the
updated,
global
frequency
these
outcomes.
Heliyon,
Journal Year:
2021,
Volume and Issue:
7(7), P. e07393 - e07393
Published: June 26, 2021
BackgroundDuring
the
COVID-19
pandemic,
health
professionals
who
are
at
frontline
of
this
crisis
have
been
facing
extreme
psychological
disorders.
This
research
aims
to
provide
an
overall
scenario
prevalence
depression,
anxiety,
stress,
as
well
insomnia
and
inspect
changes
in
these
over
time
by
analyzing
existing
evidence
during
pandemic.MethodsA
systematic
search
was
performed
on
March
30,
2021,
PubMed,
MEDLINE,
Google
Scholar
databases,
Web
Science.
To
assess
heterogeneity,
Q-test,
I2
statistics,
Meta
regression
for
publication
bias,
Eggers's
test
funnel
plot
were
used.
The
random-effect
model
subgroup
analysis
due
significant
heterogeneity.ResultsAmong
eighty-three
eligible
studies
final
synthesis,
69
(n
=
144649)
assessed
depression
37.12%
(95%
CI:
31.80–42.43),
75
147435)
reported
anxiety
41.42%
36.17–46.54),
41
82783)
stress
44.86%
36.98–52.74),
21
33370)
enunciated
43.76%
35.83–51.68).
severity
mental
problems
among
increased
January
2020
September
2020.LimitationsA
level
heterogeneity
found
measurement
tools
across
studies.ConclusionsTherefore,
it
is
emergency
develop
interventions
that
can
protect
vulnerable
groups
like
professionals.
Human Resources for Health,
Journal Year:
2022,
Volume and Issue:
20(1)
Published: March 24, 2022
Abstract
Background
COVID-19
has
challenged
health
systems
worldwide,
especially
the
workforce,
a
pillar
crucial
for
resilience.
Therefore,
strengthening
system
resilience
can
be
informed
by
analyzing
care
workers’
(HCWs)
experiences
and
needs
during
pandemics.
This
review
synthesizes
qualitative
studies
published
first
year
of
pandemic
to
identify
factors
affecting
HCWs’
their
support
pandemic.
was
conducted
using
Joanna
Briggs
Institute
methodology
scoping
reviews.
A
systematic
search
on
PubMed
applied
controlled
vocabularies.
Only
original
presenting
primary
data
were
included.
Results
161
papers
that
from
beginning
up
until
28th
March
2021
included
in
review.
Findings
presented
socio-ecological
model
as
an
analytical
framework.
At
individual
level,
impact
manifested
well-being,
daily
routine,
professional
personal
identity.
interpersonal
relationships
identified
crucial.
institutional
decision-making
processes,
organizational
aspects
availability
emerged
important
experiences.
community
morale,
norms,
public
knowledge
importance.
Finally,
at
policy
governmental
response
measures
shaped
The
lack
which
investigate
other
HCWs
than
doctors
nurses,
non-hospital
settings,
low-
lower
middle
income
countries.
Discussion
shows
HCWs,
with
multiple
contextual
impacting
needs.
To
better
understand
experiences,
comparative
investigations
are
needed
analyze
differences
across
well
within
countries,
including
institutional,
community,
levels.
Similarly,
interventions
aimed
supporting
prior
to,
after
pandemics
need
consider
circumstances.
Conclusions
Following
context-sensitive
approach
empowering
accounts
multitude
influence
could
contribute
building
sustainable
workforce
future
Frontiers in Psychiatry,
Journal Year:
2022,
Volume and Issue:
12
Published: Jan. 17, 2022
Objective
This
meta-review
aimed
to
provide
a
comprehensive
overview
of
overall
mental
health
healthcare
professionals
during
the
COVID-19
pandemic.
Method
We
conducted
literature
search
on
Academic
Search
Premier,
CINAHL,
Cochrane
Library,
and
MEDLINE.
A
predefined
eligibility
criterion
was
used
screen
articles.
The
methodology
quality
eligible
studies
assessed
using
Joanna
Briggs
Institute
checklist
for
systematic
reviews.
data
were
narratively
synthesised
in
line
with
aim.
Result
Forty
reviews
(represented
as
K
=
40),
which
reported
from
1,828
primary
(
N
)
3,245,768
participants,
met
inclusion
criteria.
findings
pooled
prevalence
indicate
that
anxiety
(16–41%,
30,
701),
depression
(14–37%,
28,
584),
stress/post-traumatic
stress
disorder
(18.6–56.5%,
24,
327)
most
prevailing
pandemic-related
conditions
affecting
workers.
Other
concerns
included
insomnia,
burnout,
fear,
obsessive-compulsive
disorder,
somatization
symptoms,
phobia,
substance
abuse,
suicidal
thoughts.
Considering
regions/countries,
highest
United-Kingdom
[22.3,
95%
Confidence
Interval
(CI):7–38,
4]
compared
other
countries,
while
Middle-East,
(41,
CI:16–60,
5)
Eastern
Mediterranean
region
(61.6,
CI:56.4–66.8,
2)
regions.
significant
risk
factors
include
female
gender,
younger
age,
being
nurse,
frontline
professional.
most-reported
coping
strategies
individual/group
psychological
support,
family/relative
training/orientation,
adequacy
personal
protective
equipment.
Conclusion
It
concluded
(nurses,
doctors,
allied
health)
have
experienced
various
issues
meta-review,
therefore,
recommends
targeted
interventions
policies
address
specific
support
worldwide
duration
pandemic
similar
future
crises.
Systematic
Review
Registration
https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD4202126200
,
identifier:
CRD42021262001.
Frontiers in Psychology,
Journal Year:
2021,
Volume and Issue:
12
Published: Sept. 21, 2021
Background:
Mental
health
burden
has
been
massively
reported
during
the
COVID-19
pandemic
period.
Aiming
to
summarise
these
data,
we
present
a
meta-review
of
meta-analyses
that
evaluated
impact
on
anxiety,
depressive
and
stress
symptoms,
psychological
distress,
post-traumatic
disorder/symptoms
(PTSD),
sleep
disturbance,
reporting
its
prevalence
general
public
(GP)
care
workers
(HCW).
Methods:
A
search
was
performed
in
PubMed,
EMBASE,
Web
Science.
Sleep
disturbances,
stress,
burnout
were
grouped
as
"Psychophysiological
stress,"
depression,
PTSD
"Psychopathology."
random-effects
model,
calculating
pooled
together
with
95%
confidence
interval
for
each
domain.
Subgroup
analyses
population
type
(GP
HCW)
mental
outcome.
For
anxiety
subgroup
analysis
performed.
Heterogeneity
is
I2.
Publication
bias
assessed
through
visual
inspection
funnel
plot,
further
tested
by
Egger's
test
trim
fill
analyses.
Results:
total
18
included.
The
psychophysiological
31.99%
(CI:
26.88-37.58,
I2
=
99.9%).
HCW
showed
higher
(37.74%,
CI:
33.26-42.45,
99.7%)
than
GP
(20.67%,
15.07-27.66,
overall
insomnia,
were,
respectively,
32.34%
25.65-39.84),
28.25%
18.12-41.20),
36%
29.31-43.54).
Psychopathology
at
26.45%
24.22-28.79,
99.9%)
sample,
similar
estimates
(HCW
26.14%,
23.37-29.12,
99.9%;
GP:
26.99%,
23.41-30.9,
27.77%
24.47-31.32),
26.93%
23.92-30.17),
20%
15.54-24.37),
respectively.
Similar
proportions
between
populations
found
27.5%,
23.78-31.55;
28.33%,
22.1-35.5)
depression
27.05%,
23.14-31.36;
26.7%,
22.32-31.59).
Asymmetry
plot
found,
slight
increase
estimate
psychopathology
(29.08%,
26.42-31.89)
after
analysis.
Conclusions:
problems
ranged
from
20
36%.
presented
population.
Systematic
Review
Registration:https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=252221,
identifier:
CRD42021252221.
International Journal of Nursing Studies,
Journal Year:
2022,
Volume and Issue:
131, P. 104272 - 104272
Published: April 28, 2022
Hospital
staff
is
at
high
risk
of
developing
mental
health
issues
during
the
coronavirus
(COVID-19)
pandemic.
However,
literature
lacks
an
overall
and
inclusive
picture
problems
with
comprehensive
analysis
among
hospital
COVID-19
To
ascertain
prevalence
anxiety,
depression
other
outcomes
as
reported
in
original
articles
A
PRISMA
2020
MOOSE
2000
compliant
umbrella
review
published
meta-analyses
observational
studies
evaluating
Systematic
searches
were
conducted
PubMed/Medline,
CINAHL,
EMBASE,
PsycINFO
from
December
1st,
2019,
until
August
13th
2021.
The
random
effects
model
was
used
for
meta-analysis,
I2
index
employed
to
assess
between-study
heterogeneity.
Publication
bias
using
Egger
test
LFK
examined.
Data
analyzed
STATA
17.0
software.
AMSTAR-2
applied
quality
assessment
systematic
reviews,
while
we
GRADE
rate
evidence.
Forty-four
1298
individual
included
final
analysis,
encompassing
16
symptoms.
One-third
workers
anxiety
(Prevalence:
29.9%,
95%
CI:27.1%
32.7%)
28.4%,
CI:25.5%
31.3%)
symptomatology,
about
40%
(95%
CI:
36.9%
42.0%)
suffered
sleeping
disorders.
Fear-related
symptoms,
reduced
well-being,
poor
life,
acute
stress
symptoms
had
highest
staff.
evidence
these
areas
varied
low
very
low.
Nurses
more
often
sleep
than
doctors,
whereas
doctors
a
higher
post-traumatic
burden
depression,
disorders
female
employees
their
male
counterparts.
Remarkably,
insomnia
affected
half
first-line
medical
pandemic
generally
high,
representing
most
robust
based
on
large
dataset
meta-analyses.
there
no
strong
confidence
body
each
outcome
assessed.
Not
registered.
having
major
impact
need
support
must
be
different
nurses
@eldi12345.
International Journal of Environmental Research and Public Health,
Journal Year:
2021,
Volume and Issue:
18(19), P. 10041 - 10041
Published: Sept. 24, 2021
The
COVID-19
pandemic
has
impacted
the
lives
of
worldwide
population.
Citizens
suffer
social,
economic,
physiological,
and
psychological
effects
this
pandemic.
Primary
sources,
scientific
articles,
secondary
bibliographic
indexes,
databases,
web
pages
were
used
for
a
consensus
critical
review.
method
was
narrative
review
available
literature
to
summarize
existing
addressing
mental
health
concerns
stressors
related
main
search
engines
in
present
research
PubMed,
SciELO,
Google
Scholar.
We
found
had
direct
impact
on
psychopathologies
such
as
anxiety,
increasing
its
ratios,
depression.
Other
syndromes
burnout
post-traumatic
stress
disorder
have
increased
with
pandemic,
showing
larger
incidence
among
medical
personnel.
Moreover,
eating
disorders
violence
also
increased.
Public
authorities
must
prepare
healthcare
systems
incidences
pathologies.
Mental
apps
are
one
tools
that
can
be
reach
general
BMJ Open,
Journal Year:
2021,
Volume and Issue:
11(9), P. e054528 - e054528
Published: Sept. 1, 2021
Objectives
To
summarise
the
evidence
relating
to
prevalence
of
anxiety
and
depression
among
healthcare
workers
(HCWs)
during
COVID-19
pandemic.
Design
An
umbrella
review
systematic
reviews
was
undertaken
using
Joanna
Briggs
Institute
(JBI)
methods.
Data
sources
The
Cochrane
database
reviews,
JBI
Evidence
Synthesis,
MEDLINE,
Web
Science,
PsycINFO,
Embase
CINAHL
were
searched
in
March
2021
for
published
English.
Eligibility
criteria
Systematic
reporting
HCWs
Two
researchers
screened
each
abstract
independently
reviewed
full
text
articles.
Study
quality
assessed
critical
appraisal
tool
degree
overlap
primary
studies
calculated.
Results
Ten
(100
unique
studies),
including
169
157
from
35
countries
included.
all
ranged
22.2%
(95%
CI
21.3%
23.1%)
33.0%
31.9%
34.1%).
physicians
(n=5820)
reported
be
between
17%
19.8%
nurses
(n=14
938)
22.8%
27%.
17.9%
17.1%
18.8%)
36%
34.9%
37.1%).
(n=643)
(n=8063)
40.4%
28%,
respectively.
Conclusions
There
is
wide
variation
evident
presence
HCWs.
In
particular,
high.
Strategies
reduce
incidence
are
urgently
required.
PROSPERO
registration
number
CRD42021238960.