Tumor-produced immune regulatory factors as a therapeutic target in cancer treatment DOI Creative Commons

Vladimir Rogovskii

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Aug. 14, 2024

Citation: Rogovskii V (2024) Tumor-produced immune regulatory factors as a therapeutic target in cancer treatment. Front. Immunol. 15:1416458. doi: 10.3389/fimmu.2024.1416458

Language: Английский

Autophagy in aging-related diseases and cancer: Principles, regulatory mechanisms and therapeutic potential DOI
Na Wu, Wenhui Zheng,

Yundong Zhou

et al.

Ageing Research Reviews, Journal Year: 2024, Volume and Issue: 100, P. 102428 - 102428

Published: July 20, 2024

Language: Английский

Citations

19
Targeting oxygenases could be a viable anti-metastatic approach in cancer therapy DOI
Pengfei Shi, Jie Xu,

Hongjuan Cui

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 143375 - 143375

Published: April 1, 2025

Language: Английский

Citations

0
Influencing immunity: role of extracellular vesicles in tumor immune checkpoint dynamics DOI Creative Commons
Ziyang Ye, Genpeng Li, Jianyong Lei

et al.

Experimental & Molecular Medicine, Journal Year: 2024, Volume and Issue: 56(11), P. 2365 - 2381

Published: Nov. 11, 2024

Immune checkpoint proteins (ICPs) serve as critical regulators of the immune system, ensuring protection against damage due to overly activated responses. However, within tumor environment, excessive ICP activation weakens antitumor immunity. Despite development numerous blockade (ICB) drugs in recent years, their broad application has been inhibited by uncertainties about clinical efficacy. A thorough understanding regulation microenvironment is essential for advancing more effective and safer ICB therapies. Extracellular vesicles (EVs), which are pivotal mediators cell-cell communication, have extensively studied found play key roles functionality ICPs. Nonetheless, a comprehensive review summarizing current knowledge crosstalk between EVs ICPs environment lacking. In this review, we summarize interactions several widely well potential implications, providing theoretical basis further investigation EV-related therapeutic approaches.

Language: Английский

Citations

2
Tumor-produced immune regulatory factors as a therapeutic target in cancer treatment DOI Creative Commons

Vladimir Rogovskii

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Aug. 14, 2024

Citation: Rogovskii V (2024) Tumor-produced immune regulatory factors as a therapeutic target in cancer treatment. Front. Immunol. 15:1416458. doi: 10.3389/fimmu.2024.1416458

Language: Английский

Citations

0