Longitudinal gut microbiome dynamics in relation to age and senescence in a wild animal population DOI Creative Commons
Sarah F. Worsley, Charli S. Davies, Chuen Zhang Lee

et al.

Molecular Ecology, Journal Year: 2024, Volume and Issue: 33(16)

Published: July 16, 2024

Abstract In humans, gut microbiome (GM) differences are often correlated with, and sometimes causally implicated in, ageing. However, it is unclear how these findings translate in wild animal populations. Studies that investigate GM dynamics change within individuals, with declines physiological condition, needed to fully understand links between chronological age, senescence the GM, but have rarely been done. Here, we use longitudinal data collected from a closed population of Seychelles warblers ( Acrocephalus sechellensis ) bacterial alpha diversity, composition stability associated host senescence. We hypothesised diversity will differ, become more variable, older adults, particularly terminal year prior death, as becomes increasingly dysregulated due remained largely invariable respect adult age did not differ an individual's year. Furthermore, there was no evidence became heterogenous senescent groups (individuals than 6 years), or Instead, environmental variables such season, territory quality time day, were strongest predictors variation warblers. These results contrast studies on captive populations some (but all) non‐human primates, suggesting deterioration may be universal hallmark species. Further work disentangle factors driving GM‐senescence relationships across different taxa.

Language: Английский

Seasonal shift of the gut microbiome synchronizes host peripheral circadian rhythm for physiological adaptation to a low-fat diet in the giant panda DOI Creative Commons
Guangping Huang, Le Wang, Jian Li

et al.

Cell Reports, Journal Year: 2022, Volume and Issue: 38(3), P. 110203 - 110203

Published: Jan. 1, 2022

Characteristics of the gut microbiome vary synchronously with changes in host diet. However, underlying effects these fluctuations remain unclear. Here, we performed fecal microbiota transplantation (FMT) diet-specific feces from an endangered mammal (the giant panda) into a germ-free mouse model. We demonstrated that butyrate-producing bacterium Clostridium butyricum was more abundant during shoot-eating season than leaf-eating season, congruent significant increase body mass. Following season-specific FMT, model resembled donor, and mice transplanted grew faster stored fat. Mechanistic investigations revealed butyrate extended upregulation hepatic circadian gene Per2, subsequently increasing phospholipid biosynthesis. Validation experiments further confirmed this causal relationship. This study seasonal shifts affect growth performance, facilitating deeper understanding host-microbe interactions wild mammals.

Language: Английский

Citations

76
Cu(II) adsorption on Poly(Lactic Acid) Microplastics: Significance of microbial colonization and degradation DOI
Ying Sun, Xuejiang Wang, Siqing Xia

et al.

Chemical Engineering Journal, Journal Year: 2021, Volume and Issue: 429, P. 132306 - 132306

Published: Sept. 8, 2021

Language: Английский

Citations

96
Diurnal oscillations in gut bacterial load and composition eclipse seasonal and lifetime dynamics in wild meerkats DOI Creative Commons
Alice Risely, Kerstin Wilhelm, Tim Clutton‐Brock

et al.

Nature Communications, Journal Year: 2021, Volume and Issue: 12(1)

Published: Oct. 14, 2021

Abstract Circadian rhythms in gut microbiota composition are crucial for metabolic function, yet the extent to which they govern microbial dynamics compared seasonal and lifetime processes remains unknown. Here, we investigate bacterial wild meerkats ( Suricata suricatta ) over a 20-year period compare diurnal, seasonal, concert, applying ratios of absolute abundance. We found that diurnal oscillations load eclipsed dynamics. Diurnal were characterised by peak Clostridium abundance at dawn, associated with temperature-constrained foraging schedules, did not decay age. Some genera exhibited fluctuations, whilst others developed age, although little support senescence very old meerkats. Strong circadian this species may reflect extreme daily temperature fluctuations typical arid-zone climates. Our findings demonstrate accounting is essential future microbiome research.

Language: Английский

Citations

61
Gut microbiota of ring-tailed lemurs (Lemur catta) vary across natural and captive populations and correlate with environmental microbiota DOI Creative Commons
Sally L. Bornbusch, Lydia K. Greene,

Sylvia Rahobilalaina

et al.

Animal Microbiome, Journal Year: 2022, Volume and Issue: 4(1)

Published: April 28, 2022

Inter-population variation in host-associated microbiota reflects differences the hosts' environments, but this characterization is typically based on studies comparing few populations. The diversity of natural habitats and captivity conditions occupied by any given host species has not been captured these comparisons. Moreover, intraspecific gut microbiota, generally attributed to diet, may also stem from differential acquisition environmental microbes-an understudied mechanism which microbiomes are directly shaped microbes. To more comprehensively characterize an ecologically flexible host, ring-tailed lemur (Lemur catta; n = 209), while investigating role acquisition, we used 16S rRNA sequencing soil sampled up 13 settings, eight wilderness Madagascar five or U.S. Based matched fecal samples, microbial source tracking examine covariation between two types consortia.The microbes varied markedly within settings. Microbial was consistently greater wild than captive lemurs, indicating that metric necessarily indicator habitat condition. Variation composition inconsistent both with a single, representative community for conspecifics universal 'signal captivity' homogenizes consortia animals. Despite similar, commercial diets lemurs continents, were compositionally most suggesting non-dietary factors govern some variability. In particular, communities across geographic locations, samples different continents being distinct, there significant context-specific microbiota.As one broadest, single-species investigations primate our study highlights sensitive multiple scales differences. This finding begs reevaluation simple 'captive vs. wild' dichotomy. Beyond important implications animal care, health, conservation, mediate aspects further expands framework how interact landscapes.

Language: Английский

Citations

44
Synchrony and idiosyncrasy in the gut microbiome of wild baboons DOI
Johannes R. Björk, Mauna Dasari,

Kim Roche

et al.

Nature Ecology & Evolution, Journal Year: 2022, Volume and Issue: 6(7), P. 955 - 964

Published: June 2, 2022

Language: Английский

Citations

41
Drivers of gut microbiome variation within and between groups of a wild Malagasy primate DOI Creative Commons
Katja Rudolph, Dominik Schneider, Claudia Fichtel

et al.

Microbiome, Journal Year: 2022, Volume and Issue: 10(1)

Published: Feb. 9, 2022

Various aspects of sociality can benefit individuals' health. The host social environment and its relative contributions to the host-microbiome relationship have emerged as key topics in microbial research. Yet, understanding mechanisms that lead structural variation microbiome, collective metacommunity an animal's network, remains difficult since multiple processes operate simultaneously within among animal networks. Here, we examined potential drivers convergence gut microbiome on scales seven neighbouring groups wild Verreaux's sifakas (Propithecus verreauxi) - a folivorous primate Madagascar. Over four field seasons, collected 519 faecal samples 41 animals determined communities via 16S 18S rRNA gene amplicon analyses. First, whether group members share more similar microbiota if diet, home range overlap, or habitat similarity drive between-group communities, accounting for seasonality. Next, within-group by examining effects contact rates, male rank, maternal relatedness. To explore intrinsic community structure, investigated age, sex, glucocorticoid metabolites, female reproductive state. We found differ alpha diversity, while none environmental predictors explained patterns variation. Maternal relatedness played important role homogeneity may also explain why adult shared least microbiota. Also, dominant males differed their bacterial composition from mates, which might be driven rank-related differences physiology scent-marking behaviours. Links state, metabolites were not detected. Environmental factors define general set-up population-specific microbiota, but stronger impact this species. Video abstract.

Language: Английский

Citations

39
Bacteroidetes to Firmicutes: captivity changes the gut microbiota composition and diversity in a social subterranean rodent DOI Creative Commons
Hanna M. Bensch,

Conny Tolf,

Jonas Waldenström

et al.

Animal Microbiome, Journal Year: 2023, Volume and Issue: 5(1)

Published: Feb. 10, 2023

Abstract Background In mammals, the gut microbiota has important effects on health of their hosts. Recent research highlights that animal populations live in captivity often differ diversity and composition from wild populations. However, changes may occur when animals move to remain difficult predict factors generating such differences are poorly understood. Here we compare bacterial captive Damaraland mole-rats ( Fukomys damarensis ) originating a population southern Kalahari Desert characterise one generation next long-lived, social rodent species. Results We found clear divergence mole-rats. Although dominating higher-rank taxa were same two groups, had an increased ratio relative abundance Firmicutes Bacteroidetes compared animals. The Amplicon Sequence Variants (ASVs) strongly associated with commonly members families as those Captive much higher ASV richness wild-caught animals, explained by within Firmicutes. Conclusion hosts differs substantially largest between groups shifts abundances Bacteroidetes.

Language: Английский

Citations

26
Flexible host–microbe interaction aid adaptation of black-necked crane to seasonal shifts DOI Creative Commons

Ruifeng Ma,

Shujuan Ma,

Yujia Zhang

et al.

Global Ecology and Conservation, Journal Year: 2025, Volume and Issue: unknown, P. e03458 - e03458

Published: Jan. 1, 2025

Language: Английский

Citations

1
High-Altitude Drives the Convergent Evolution of Alpha Diversity and Indicator Microbiota in the Gut Microbiomes of Ungulates DOI Creative Commons
Xibao Wang,

Xiaoyang Wu,

Yongquan Shang

et al.

Frontiers in Microbiology, Journal Year: 2022, Volume and Issue: 13

Published: July 7, 2022

Convergent evolution is an important sector of evolutionary biology. High-altitude environments are one the extreme for animals, especially in Qinghai Tibet Plateau, driving inquiry whether, under broader phylogeny, high-altitude factors drive convergent Artiodactyla and Perissodactyla gut microbiomes. Therefore, we profiled microbiome at high low altitudes using 16S rRNA gene sequencing. According to cluster analyses, compositions were not grouped together far from those low-altitude Perissodactyla. The Wilcoxon’s test ungulates showed significantly higher Sobs Shannon indices than ungulates. At phylum level, Firmicutes Patescibacteria enriched microbiomes ungulates, which also displayed a Firmicutes/Bacteroidetes value family Ruminococcaceae, Christensenellaceae, Saccharimonadaceae Our results indicated that OH FH groups shared two genera, Christensenellaceae_R_7_group Candidatus_Saccharimonas . These findings altitude cannot surpass order level ungulate composition but can alpha diversity indicator microbiota Overall, this study provides novel perspective understanding adaptation environments.

Language: Английский

Citations

35
Glucocorticoids coordinate changes in gut microbiome composition in wild North American red squirrels DOI Creative Commons
Lauren Petrullo,

Tiantian Ren,

Martin Wu

et al.

Scientific Reports, Journal Year: 2022, Volume and Issue: 12(1)

Published: Feb. 16, 2022

The gut microbiome impacts host health and fitness, in part through the diversification of metabolic function pathogen protection. Elevations glucocorticoids (GCs) appear to reduce diversity experimental studies, suggesting that a loss microbial may be negative consequence increased GCs. However, given ecological factors like food availability population density independently influence both GCs diversity, understanding how these structure GC-microbiome relationship is crucial interpreting its significance wild populations. Here, we used an framework investigate between North American red squirrels (Tamiasciurus hudsonicus). As expected, higher predicted lower increase taxa. Surprisingly, but line with prior empirical studies on animals, gastrointestinal pathogens decreased as increased. Both dietary heterogeneity upcoming pulse exhibited direct effects whereas conspecific reproductive activity impacted indirectly via changes Our results provide evidence gut-brain axis highlight importance situating GC-gut within framework.

Language: Английский

Citations

31