Optical nanomaterial-based detection of biomarkers in liquid biopsy
Journal of Hematology & Oncology,
Journal Year:
2024,
Volume and Issue:
17(1)
Published: March 14, 2024
Abstract
Liquid
biopsy,
which
is
a
minimally
invasive
procedure
as
an
alternative
to
tissue
has
been
introduced
new
diagnostic/prognostic
measure.
By
screening
disease-related
markers
from
the
blood
or
other
biofluids,
it
promises
early
diagnosis,
timely
prognostication,
and
effective
treatment
of
diseases.
However,
there
will
be
long
way
until
its
realization
due
conceptual
practical
challenges.
The
biomarkers
detected
by
liquid
such
circulating
tumor
cell
(CTC)
DNA
(ctDNA),
are
extraordinarily
rare
often
obscured
abundance
normal
cellular
components,
necessitating
ultra-sensitive
accurate
detection
methods
for
advancement
biopsy
techniques.
Optical
biosensors
based
on
nanomaterials
open
important
opportunity
in
because
their
enhanced
sensing
performance
with
simple
properties.
In
this
review
article,
we
summarized
recent
innovations
optical
demonstrate
sensitive
protein,
peptide,
ctDNA,
miRNA,
exosome,
CTCs.
Each
study
prepares
tailored
design
enhance
meet
requirements
each
biomarker.
unique
characteristics
metallic
nanoparticles
(NPs),
quantum
dots,
upconversion
NPs,
silica
polymeric
carbon
exploited
mechanisms.
These
advances
using
give
us
overcome
challenging
issues
provide
resource
understanding
unknown
well
mechanism
disease.
Graphical
abstract
Language: Английский
Application of Nanobiosensor Engineering in the Diagnosis of Neurodegenerative Disorders
Results in Engineering,
Journal Year:
2024,
Volume and Issue:
24, P. 102790 - 102790
Published: Sept. 5, 2024
Language: Английский
Photoluminescence-based biosensor for the detection of antibodies against SARS-CoV-2 virus proteins by ZnO tetrapod structure integrated within microfluidic system
Roman Viter,
No information about this author
Iryna Tepliakova,
No information about this author
Maryia Drobysh
No information about this author
et al.
The Science of The Total Environment,
Journal Year:
2024,
Volume and Issue:
939, P. 173333 - 173333
Published: May 17, 2024
Language: Английский
A Comparative Analysis of Optical Biosensors for Rapid Detection of SARS‐CoV‐2 and Influenza
Biotechnology and Bioengineering,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 24, 2025
ABSTRACT
Airborne
pathogens,
such
as
influenza
and
SARS‐CoV‐2,
pose
significant
health
risks.
While
traditional
diagnostic
methods
have
limitations,
optical
biosensors
offer
a
promising
solution
due
to
their
rapid,
sensitive,
cost‐effective
nature.
This
review
focuses
on
the
application
of
biosensors,
including
colorimetry,
surface
plasmon
resonance,
surface‐enhanced
Raman
spectroscopy,
fluorescence
techniques,
for
detection
SARS‐CoV‐2.
We
discuss
advantages
these
potential
point‐of‐care
testing
early
disease
detection.
By
addressing
limitations
existing
exploring
emerging
technologies,
can
play
crucial
role
in
combating
spread
airborne
pathogens.
provides
comprehensive
overview
biosensor
techniques
both
SARS‐CoV‐2
influenza,
gap
literature.
Language: Английский
Solution processing for colloidal nanoparticle thin film: From fundamentals to applications
WooSeok Jeong,
No information about this author
Hyeonseok Lee,
No information about this author
Yun Jae Hwang
No information about this author
et al.
Advances in Colloid and Interface Science,
Journal Year:
2025,
Volume and Issue:
342, P. 103538 - 103538
Published: April 28, 2025
Language: Английский
Polysaccharide Hydrogel-Assisted Biosensing Platforms for Point-of-Care Use
Biosensors,
Journal Year:
2025,
Volume and Issue:
15(1), P. 13 - 13
Published: Jan. 2, 2025
Point-of-care
(POC)
use
is
one
of
the
essential
goals
biosensing
platforms.
Because
increasing
demand
for
testing
cannot
be
met
by
a
centralized
laboratory-based
strategy,
rapid
and
frequent
at
right
time
place
will
key
to
health
safety.
To
date,
however,
there
are
still
difficulties
in
developing
simple
affordable,
as
well
sensitive
effective,
platform
that
enables
POC
use.
In
terms
materials,
hydrogels,
unique
family
water-absorbing
biocompatible
polymers,
have
emerged
promising
components
development
biosensors.
Combinations
hydrogels
various
additional
applications,
such
hydrophilic
coatings,
nanoscale
filtration,
stimuli-responsive
signal
enhancement,
biodegradation.
this
review,
we
highlight
recent
efforts
develop
hydrogel-assisted
platforms
use,
especially
focusing
on
polysaccharide
like
agarose,
alginate,
chitosan,
so
on.
We
first
discuss
pros
cons
practical
applications
then
introduce
case
studies
test
different
formats,
paper-based
analytical
devices
(PADs),
microfluidic
devices,
independent
believe
analysis
present
review
provides
information
resource-limited
settings.
Language: Английский