Engineered local delivery of extracellular vesicles loaded with si-TNF-α, via a core-sheath 3D-bio-printed scaffold as an effective wound dressing DOI
Saeid Vakilian,

Fatemeh Jamshidi‐Adegani,

Fahad Al‐Fahdi

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: unknown, P. 106189 - 106189

Published: Sept. 1, 2024

Language: Английский

CD147 in Keloid Therapy: Mechanisms and Future Directions DOI

Paridokht Karimian

Burns, Journal Year: 2025, Volume and Issue: unknown, P. 107534 - 107534

Published: May 1, 2025

Language: Английский

Citations

0
Use of Hydrogels in Regenerative Medicine: Focus on Mechanical Properties DOI Open Access
Flavia Carton, Manuela Rizzi, Elena Canciani

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(21), P. 11426 - 11426

Published: Oct. 24, 2024

Bioengineered materials represent an innovative option to support the regenerative processes of damaged tissues, with final objective creating a functional environment closely mimicking native tissue. Among different available biomaterials, hydrogels solution choice for tissue regeneration, thanks easy synthesis process and highly tunable physical mechanical properties. Moreover, are biocompatible biodegradable, able integrate in biological environments cellular interactions order restore tissues' functionality. This review offers overview current knowledge concerning hydrogel characterization recent achievements their experimental use supporting skin, bone, cartilage, muscle regeneration. The currently vitro vivo results great interest, highlighting need carefully designed controlled preclinical studies clinical trials transition these biomaterials from bench bedside.

Language: Английский

Citations

3
Current multi-scale biomaterials for tissue regeneration following spinal cord injury DOI

Y Zhang,

Zhonghuan Wu,

Junfeng Wu

et al.

Neurochemistry International, Journal Year: 2024, Volume and Issue: 178, P. 105801 - 105801

Published: July 5, 2024

Language: Английский

Citations

2
Chitosan membranes incorporating Aloe vera glycolic extract with joint synthesis of silver nanoparticles for the treatment of skin lesions DOI Creative Commons
Venâncio Alves Amaral, Victoria L. Santana,

Erika S. Lisboa

et al.

Drug Delivery and Translational Research, Journal Year: 2024, Volume and Issue: 15(4), P. 1376 - 1392

Published: July 30, 2024

New wound dressings based on polymeric membranes have been widely exploited for clinical applications to assist in the healing process and prevent additional complications (e.g., bacterial infections). Here we propose development of a new production method chitosan, incorporating glycolic extract Aloe vera with joint synthesis silver nanoparticles use as bioactive dressing. The were obtained by casting technique, their morphological, physicochemical characteristics, degree swelling, degradation profile antimicrobial activity evaluated. Morphological analyzes confirmed presence membrane. chemical compatibility between materials was demonstrated through thermal analysis (TGA DSC) combined ATR-FTIR tests, showing complexation (Mb-Ch-Ex.Av-NPs). All characterized hydrophilic material (with contact angle (ө) < 90°); however, highest swelling chitosan. (Mb-Ch) membrane (69.91 ± 5.75%) lowest Mb-Ch-Ex.Av-NPs (26.62 8.93%). On other hand, higher (77.85 7.51%) lower Mb-Ch (57.60 2.29%). manufactured showed against Escherichia coli Staphylococcus aureus. Our work translucent flexible chitosan-based membranes, dressing, proven activity.

Language: Английский

Citations

2
Silk Fibroin Nanofibers: Advancements in Bioactive Dressings through Electrospinning Technology for Diabetic Wound Healing DOI Creative Commons
Afaf Aldahish,

S. Nirenjen,

Rajalakshimi Vasudevan

et al.

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(10), P. 1305 - 1305

Published: Sept. 30, 2024

Non-healing diabetic wounds represent a significant clinical challenge globally, necessitating innovative approaches in drug delivery to enhance wound healing. Understanding the pathogenesis of these is crucial for developing effective treatments. Bioactive dressings and polymeric nanofibers have emerged as promising modalities, with silk biomaterials gaining attention their unique properties

Language: Английский

Citations

2
Biomimetic superparamagnetic gelatin/chitosan asymmetric fibrous membrane for accelerating wound healing under static magnetic field DOI
Jingxi Wang, Kun Li,

Yunxue Jia

et al.

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 347, P. 122717 - 122717

Published: Sept. 6, 2024

Language: Английский

Citations

1
Engineered local delivery of extracellular vesicles loaded with si-TNF-α, via a core-sheath 3D-bio-printed scaffold as an effective wound dressing DOI
Saeid Vakilian,

Fatemeh Jamshidi‐Adegani,

Fahad Al‐Fahdi

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: unknown, P. 106189 - 106189

Published: Sept. 1, 2024

Language: Английский

Citations

0