Preparation methods, applications, toxicity and mechanisms of silver nanoparticles as bactericidal agent and superiority of green synthesis method

Heliyon, Journal Year: 2024, Volume and Issue: 10(17), P. e36539 - e36539

Published: Aug. 23, 2024

Silver nanoparticles (SNPs) are a type of nanomaterial with wide applications in water treatment, medicine, food packaging, and industrial processes. Their unique optical, electrical, thermal conductivity, biological properties distinguish them from other metal ions liken to noble metals like gold copper. The present review explores the diverse applications, preparation techniques, mechanism action SNPs, SNPs focusing on their bactericidal activities potential impacts human health. Different methods, encompassing chemical, physical, were reviewed analyzed comprehend effect SNPs. Studies revealed that exhibit excellent antibactericidal properties. Mechanisms underlying antimicrobial effects explored, primarily pathogen-scavenging activities. Despite promising benefits toxicity health must be carefully managed. Regulatory standards, such as those set by WHO USEPA; establish maximum tolerable limit 0.1 mg/L mitigate risks associated SNP exposure. It is recommended continue research into safer alternative formulations minimize while maximizing beneficial across different industries.

Language: Английский

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Recent Advances in Silica-Based Nanomaterials for Enhanced Tumor Imaging and Therapy

ACS Applied Bio Materials, Journal Year: 2024, Volume and Issue: 7(11), P. 7133 - 7169

Published: Nov. 4, 2024

Cancer remains a formidable challenge, inflicting profound physical, psychological, and financial burdens on patients. In this context, silica-based nanomaterials have garnered significant attention for their potential in tumor imaging therapy owing to exceptional properties, such as biocompatibility, customizable porosity, versatile functionalization capabilities. This review meticulously examines the latest advancements application of therapy. It underscores enhancing various cancer modalities, including fluorescence imaging, magnetic resonance computed tomography, positron emission ultrasound multimodal approaches. Moreover, delves into therapeutic efficacy chemotherapy, radiotherapy, phototherapy, immunotherapy, gas therapy, sonodynamic chemodynamic starvation gene Critical evaluations biosafety profiles degradation pathways these within biological environments are also presented. By discussing current challenges prospects, aims provide nuanced perspective clinical translation nanomaterials, thereby highlighting promise revolutionizing diagnostics, enabling real-time monitoring responses, advancing personalized medicine.

Language: Английский

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Multigenerational exposure to silica nanoparticles causes severe fertility loss in Caenorhabditis elegans

Journal of Nanoparticle Research, Journal Year: 2025, Volume and Issue: 27(4)

Published: April 1, 2025

Language: Английский

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Advancements in Nanotechnology for Targeted and Controlled Drug Delivery in Hematologic Malignancies: Shaping the Future of Targeted Therapeutics

Applied Biosciences, Journal Year: 2025, Volume and Issue: 4(1), P. 16 - 16

Published: March 5, 2025

Hematologic malignancies, including leukemia, lymphoma, and multiple myeloma, pose significant therapeutic challenges due to their heterogeneity high relapse rates. Nanotechnology has emerged as a promising avenue for precision drug delivery in these allowing enhanced concentration at tumor sites reducing systemic toxicity. Recent developments nanocarriers—such liposomes, polymeric nanoparticles, inorganic nanoparticles—have enabled targeted approaches, utilizing molecular markers specific malignant cells increase efficacy while minimizing adverse effects. Evidence from preclinical clinical studies underscores the potential of nanotechnology improve patient outcomes by facilitating controlled release, improved bioavailability, reduced However, translating advancements into practice requires further research validate safety efficacy. This review provides comprehensive analysis latest innovations hematologic addressing current achievements future directions integrating approaches Clinical Hemato-Oncology.

Language: Английский

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Recent Research Advances in Infection and Treatment of Hybrid Biofilms

Advances in Clinical Medicine, Journal Year: 2025, Volume and Issue: 15(04), P. 3218 - 3225

Published: Jan. 1, 2025

Language: Английский

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The Genetic and Epigenetic Toxicity of Silica Nanoparticles: An Updated Review

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 19, P. 13901 - 13923

Published: Dec. 1, 2024

Silica nanoparticles (SiNPs) are widely used in biomedical fields, such as drug delivery, disease diagnosis, and molecular imaging. An increasing number of consumer products containing SiNPs being without supervision, the toxicity to human body is becoming a major problem. contact various ways cause damage structure function genetic material, potentially leading carcinogenesis, teratogenicity infertility. This review summarizes SiNPs-induced epigenetic toxicity, especially germ cells, explore their potential mechanisms. material mainly by inducing oxidative stress. Furtherly, mechanisms discussed detail for first time. alter DNA methylation, miRNA expression, histone modification inhibit chromatin remodeling regulating epigenetic-related enzymes transcription factors. beneficial investigating solutions avoid provide guidance better application field.

Language: Английский

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Research progress of nanoparticles in diagnosis and treatment of hepatocellular carcinoma

Open Life Sciences, Journal Year: 2024, Volume and Issue: 19(1)

Published: Jan. 1, 2024

Abstract Hepatocellular carcinoma (HCC) is among the most common malignant liver tumors. Despite progress in anticancer drugs and surgical approaches, early detection of HCC remains challenging, often leading to late-stage diagnosis where rapid disease progression precludes intervention, leaving chemotherapy as only option. However, systemic toxicity, low bioavailability, significant adverse effects lead resistance, rendering treatments ineffective for many patients. This article outlines how nanoparticles, following functional modification, offer high sensitivity, reduced drug extended duration action, enabling precise targeting tissues. Combined with other therapeutic modalities imaging techniques, this significantly enhances diagnosis, treatment, long-term prognosis HCC. The advent nanomedicine provides new methodologies strategies integrated treatment

Language: Английский

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Ultrasound characterization of LUDOX® nanofluids

Journal of Molecular Liquids, Journal Year: 2024, Volume and Issue: unknown, P. 126255 - 126255

Published: Oct. 1, 2024

Language: Английский

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Anti-cancer and immunomodulatory photodynamic therapy application of novel porphyrin derivatives

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 104, P. 106513 - 106513

Published: Dec. 10, 2024

Language: Английский

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