International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 666, P. 124734 - 124734
Published: Sept. 28, 2024
Language: Английский
International Medical Science Research Journal, Journal Year: 2024, Volume and Issue: 4(2), P. 126 - 140
Published: Feb. 2, 2024
The fusion of Artificial Intelligence (AI) and healthcare heralds a new era innovation transformation, yet it is not without its ethical quandaries. This comprehensive review traverses the intricate landscape where AI meets healthcare, delving into dilemmas that arise alongside practical applications. considerations span spectrum, encompassing issues patient privacy, transparency, accountability, inadvertent perpetuation biases within algorithms. Privacy concerns emerge as central dilemma providers leverage to process vast amounts data. Striking delicate balance between harnessing power for diagnostic predictive purposes safeguarding sensitive medical information critical challenge. Moreover, scrutinizes implications algorithms their potential perpetuate biases, inadvertently exacerbating health disparities. A nuanced examination bias mitigation strategies becomes imperative ensure technologies contribute equitable outcomes. In tandem with considerations, illuminates applications reshaping landscape. AI-driven diagnostics, modeling, personalized treatment plans transformative tools, enhancing clinical decision-making efficient allocation resources, streamlined workflows, acceleration drug discovery processes showcase tangible benefits integration. aspires guide practitioners, policymakers, technologists in navigating crossroads healthcare. By fostering an awareness pitfalls emphasizing responsible development, stakeholders can collaboratively shape future augments delivery, upholds standards, ultimately improves quality care. Keywords: AI, Healthcare, Ethics, Review, Application.
Language: Английский
Citations
26
Frontiers in Bioengineering and Biotechnology, Journal Year: 2024, Volume and Issue: 12
Published: May 31, 2024
Myocardial infarction (MI) stands as a prominent contributor to global cardiovascular disease (CVD) mortality rates. Acute MI (AMI) can result in the loss of large number cardiomyocytes (CMs), which adult heart struggles replenish due its limited regenerative capacity. Consequently, this deficit CMs often precipitates severe complications such failure (HF), with whole transplantation remaining sole definitive treatment option, albeit constrained by inherent limitations. In response these challenges, integration bio-functional materials within cardiac tissue engineering has emerged groundbreaking approach significant potential for replacement. Bioengineering strategies entail fortifying or substituting biological tissues through orchestrated interplay cells, methodologies, and innovative materials. Biomaterial scaffolds, crucial paradigm, provide essential microenvironment conducive assembly functional encapsulating contracting cells. Indeed, field witnessed remarkable strides, largely owing application biomaterial scaffolds. However, complexities persist, necessitating further exploration innovation. This review delves into pivotal role scaffolds engineering, shedding light on their utilization, challenges encountered, promising avenues future advancement. By critically examining current landscape, we aim catalyze progress toward more effective solutions regeneration ultimately, improved outcomes patients grappling ailments.
Language: Английский
Citations
23
ACS Omega, Journal Year: 2025, Volume and Issue: 10(1), P. 1207 - 1225
Published: Jan. 3, 2025
Manufacturing bioactive materials for drug delivery involves developing that interact with biological tissues to release drugs in a controlled and targeted manner. The goal is optimize therapeutic efficacy reduce side effects by combining knowledge from engineering, biology, pharmacology. This study presents detailed bibliometric analysis, exploring the keywords "manufacturing," "bioactive materials," "drug delivery" identify highlight significant advancements field. From Web of Science, 36,504 articles were analyzed, 171 selected deeper identifying key journals, countries, institutions, authors. results field's interdisciplinary nature, grouped into four main themes, including regenerative medicine, scaffolds, three-dimensional (3D) printing, glass, tissue engineering. Future research this area will focus on more effective precise systems using technologies like 3D printing nanotechnology enhance customization control release, aiming efficient therapies.
Language: Английский
Citations
3
Bioprinting, Journal Year: 2025, Volume and Issue: 45, P. e00386 - e00386
Published: Jan. 5, 2025
Language: Английский
Citations
2
Micromachines, Journal Year: 2025, Volume and Issue: 16(2), P. 174 - 174
Published: Jan. 31, 2025
Magnetic polymeric conduits are developing as revolutionary materials in regenerative medicine, providing exceptional benefits directing tissue healing, improving targeted medication administration, and facilitating remote control via external magnetic fields. The present article offers a thorough examination of current progress the design, construction, functionalization these hybrid systems. integration nanoparticles into matrices confers distinctive features, including regulated alignment, improved cellular motility, medicinal delivery, while preserving structural integrity. Moreover, incorporation multifunctional attributes, such electrical conductivity for cerebral stimulation optical characteristics real-time imaging, expands their range applications. Essential studies indicate that dimensions, morphology, surface chemistry, composition significantly affect biocompatibility, degrading characteristics, overall efficacy. Notwithstanding considerable advancements, issues concerning long-term biodegradability, scalability persist, addition to must uniform regulatory frameworks facilitate clinical translation. Progress additive manufacturing nanotechnology is overcoming obstacles, creation dynamic adaptive conduit structures designed particular biomedical requirements. conduits, by integrating usefulness safety, set transform therapies, presenting new avenue customized medicine advanced healthcare solutions.
Language: Английский
Citations
2
Critical Reviews in Oncology/Hematology, Journal Year: 2025, Volume and Issue: unknown, P. 104653 - 104653
Published: Feb. 1, 2025
Language: Английский
Citations
2
Annals of Biomedical Engineering, Journal Year: 2024, Volume and Issue: 52(5), P. 1184 - 1194
Published: Feb. 28, 2024
Language: Английский
Citations
10
International Journal of Applied Pharmaceutics, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 11
Published: Jan. 7, 2025
3 Dimensional (3D) printing has seemed to be the technology of radical development for pharmaceutical industry, particularly in medical device manufacturing. The current review elaborates on applications 3D printing, challenges, and potentials devices. allows complicated personalized devices with accuracy cost-effectiveness as never before, bringing key this fields prostheses, orthoses, surgical guides, audiology devices, bioresorbable implants. It brings along customization, better pre-operative planning, new drug delivery systems, but there are quality control regulatory challenges faced: material selection, process validation, sterilization, scalability. In view upcoming technology, bodies having update their guidelines ensure continued safety efficacy. On road ahead, artificial intelligence, nanotechnology, 4 (4D) future developments could make sophisticated equipment change management outcome diseases. While opens up newer routes innovation major concerns issues scalability matters. This will thus a significant impact healthcare through these coming decades, changes global research landscapes.
Language: Английский
Citations
1
Biomedicines, Journal Year: 2025, Volume and Issue: 13(1), P. 167 - 167
Published: Jan. 12, 2025
Background/Objectives: The dual forces of structured inquiry and serendipitous discovery have long shaped neuropsychiatric research, with groundbreaking treatments such as lithium ketamine resulting from unexpected discoveries. However, relying on chance is becoming increasingly insufficient to address the rising prevalence mental health disorders like depression schizophrenia, which necessitate precise, innovative approaches. Emerging technologies artificial intelligence, induced pluripotent stem cells, multi-omics potential transform this field by allowing for predictive, patient-specific interventions. Despite these advancements, traditional methodologies animal models single-variable analyses continue be used, frequently failing capture complexities human conditions. Summary: This review critically evaluates transition serendipity precision-based in research. It focuses key innovations dynamic systems modeling network-based approaches that use genetic, molecular, environmental data identify new therapeutic targets. Furthermore, it emphasizes importance interdisciplinary collaboration human-specific overcoming limitations Conclusions: We highlight precision psychiatry’s transformative revolutionizing care. paradigm shift, combines cutting-edge systematic frameworks, promises increased diagnostic accuracy, reproducibility, efficiency, paving way tailored better patient outcomes
Language: Английский
Citations
1
International Journal of Pharmaceutics, Journal Year: 2025, Volume and Issue: unknown, P. 125217 - 125217
Published: Jan. 1, 2025
Language: Английский
Citations
1