Journal of Material Science and Technology, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 1, 2024
Language: Английский
Journal of Material Science and Technology, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 1, 2024
Language: Английский
AAPS PharmSciTech, Journal Year: 2025, Volume and Issue: 26(1)
Published: Jan. 8, 2025
Language: Английский
Citations
6Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 106599 - 106599
Published: Jan. 1, 2025
Language: Английский
Citations
1AAPS PharmSciTech, Journal Year: 2025, Volume and Issue: 26(4)
Published: April 4, 2025
Language: Английский
Citations
1Next research., Journal Year: 2025, Volume and Issue: unknown, P. 100160 - 100160
Published: Jan. 1, 2025
Language: Английский
Citations
0AAPS PharmSciTech, Journal Year: 2025, Volume and Issue: 26(3)
Published: March 6, 2025
Language: Английский
Citations
0International Journal of Pharmaceutics X, Journal Year: 2025, Volume and Issue: unknown, P. 100328 - 100328
Published: March 1, 2025
Infected wounds are common clinical injuries that often complicated by inflammation and oxidative stress due to bacterial invasion. These typically suffer from impaired vascularization, which delays healing increases the risk of complications such as sepsis chronic wounds. Therefore, developing an effective treatment for infected is highly necessary. Egg white can promote cell regeneration repair, while chitosan in resisting Sildenafil believed have potential angiogenesis. Based on these properties, we prepared a new type hydrogel using egg framework, loaded with sildenafil (CEHS). The combines benefits its components, exhibiting good biocompatibility promoting proliferation migration NIH 3T3 (3T3) cells human umbilical vein endothelial (HUVEC), well angiogenesis HUVEC. It also exhibits significant antioxidant, anti-inflammatory, antibacterial properties against Escherichia coli (E. coli) Staphylococcus aureus (S. aureus). Additionally, mouse model wounds, CEHS effectively promoted wound through excellent antioxidant anti-inflammatory activity, pro-angiogenic effects. In summary, this simple-to-prepare, multifunctional natural shows great promise
Language: Английский
Citations
0Pharmacological Research - Modern Chinese Medicine, Journal Year: 2025, Volume and Issue: 15, P. 100622 - 100622
Published: April 28, 2025
Language: Английский
Citations
0International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 313, P. 144251 - 144251
Published: May 15, 2025
Language: Английский
Citations
0Journal of drug targeting, Journal Year: 2024, Volume and Issue: 32(9), P. 1139 - 1153
Published: July 23, 2024
The use of topical antimicrobials in wound healing presents challenges like risk drug resistance and toxicity to local tissue. Simvastatin (SIM), a lipid-lowering agent which reduces the cardiovascular events, is repurposed for its pleiotropic effect healing. A bioactive bioadhesive polymer-based film forming spray (FFS) formulation SIM was designed using chitosan, collagen, hyaluronic acid optimised by employing DoE approach. Optimised demonstrated moderate viscosity (12.5 ± 0.3 cP), rapid formation (231 5.6 s), flexibility, tensile strength sustained release (T80 - time 80% 9.05 0.7 h). Scanning electron microscopy (SEM) verified uniformly dispersed within composite polymer matrix. FFS antimicrobial activity against gram positive negative bacteria.
Language: Английский
Citations
1Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 101, P. 106187 - 106187
Published: Sept. 12, 2024
Language: Английский
Citations
1