Rh-Catalyzed Functionalization of N-Heterocycles Through C–H Activation DOI
Sanjeev Kumar, Vinaykumar Kanchupalli

Topics in heterocyclic chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 89 - 157

Published: Jan. 1, 2024

Language: Английский

Rhodium-catalysed additive-free carbonylation of benzamides with diethyl dicarbonate as a carbonyl source DOI
Hirotsugu Suzuki,

Seigo Kiyobe,

Takanori Matsuda

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(14), P. 2744 - 2748

Published: Jan. 1, 2024

A rhodium-catalysed carbonylation of benzamides has been developed by employing diethyl dicarbonate as a stable and easy-to-handle carbonyl source.

Language: Английский

Citations

3
Rhodium-Catalyzed Intramolecular Acylation of 2-(Indol-1-yl)-benzoic Acids under Redox-Neutral Conditions DOI
Hirotsugu Suzuki, Takanori Matsuda,

Yosuke Takemura

et al.

Synlett, Journal Year: 2023, Volume and Issue: 34(16), P. 1894 - 1898

Published: May 8, 2023

Abstract We developed a novel access to indoloindolone by rhodium-catalyzed intramolecular acylation of 2-(indol-1-yl)benzoic acids. This reaction proceeds via the in situ formation mixed anhydride under redox-neutral conditions. Preliminary mechanistic investigations revealed that formed participates C–H activation step, which is facilitated RhI catalyst. The utility this was demonstrated large-scale reaction.

Language: Английский

Citations

3
Rhodium-Catalyzed Decarbonylative Intramolecular Arylation of 2-(1H-Indole-1-carbonyl)benzoic Acids DOI
Hirotsugu Suzuki, Takanori Matsuda,

Yosuke Takemura

et al.

Synlett, Journal Year: 2024, Volume and Issue: 35(17), P. 2037 - 2041

Published: Feb. 28, 2024

Abstract We developed a redox-neutral synthesis of isoindoloindolone via intramolecular arylation 2-(1H-indole-1-carbonyl)benzoic acids. This protocol facilitates the formation various substituted isoindoloindolones in yields ranging from 17% to 80%. Our mechanistic investigations indicate pivotal role NaI: iodide anion promotes desired isoindoloindolone, and sodium cation suppresses acylated byproducts, thereby enabling selective acceptable yields.

Language: Английский

Citations

0
Rhodium-catalysed additive-free alkoxycarbonylation of indoles: 2,4,6-trimethylbenzoic acid-based carbonate anhydrides as a versatile alkoxycarboxyl source DOI Creative Commons
Hirotsugu Suzuki, Yuki Ito,

Kentaro Yabe

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(16), P. 3209 - 3214

Published: Jan. 1, 2024

We developed a rhodium-catalysed alkoxycarbonylation of indoles, characterised by employing stable and easily available 2,4,6-trimethylbenzoic acid-based carbonate anhydrides.

Language: Английский

Citations

0
Rh-Catalyzed Functionalization of N-Heterocycles Through C–H Activation DOI
Sanjeev Kumar, Vinaykumar Kanchupalli

Topics in heterocyclic chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 89 - 157

Published: Jan. 1, 2024

Language: Английский

Citations

0