Frontiers in Pharmacology,
Journal Year:
2023,
Volume and Issue:
14
Published: Oct. 17, 2023
Background:
Polypharmacy,
defined
as
the
simultaneous
use
of
multiple
medications
by
a
patient,
is
worldwide
problem
rising
prevalence.
Paving
way
for
drug
interactions,
adverse
reactions
and
non-adherence,
it
leads
to
negative
health
outcomes,
increased
healthcare
services
costs.
Since
closely
related
multimorbidity,
peaks
in
older
adults.
So
far,
not
many
polypharmacy
management
programs
elderly
have
been
introduced
practice.
However,
due
rapid
ageing
European
societies,
there
an
urgent
need
implement
them
more
widely.
Objective:
The
aim
this
study
was
benchmark
available
Europe
creating
dedicated
benchmarking
application.
Methods:
It
cross-sectional
based
on
online
survey
targeting
professionals
other
stakeholders
across
countries.
Data
collected
were
reused
design
Results:
As
911
respondents
from
all
but
two
EU
countries
took
part
study.
Out
participants,
496
(54.4%)
reported
availability
various
activities
or
formal
that
known
them.
These
had
goals,
which
improved
patient
safety
indicated
most
common
objective
(65.1%
cases).
typical
settings
such
primary
care
(49.4%),
with
pharmacists
doctors
being
often
those
providing
(61.7%
35.5%
cases,
respectively).
Vast
majority
applied
diverse
forms
reviews.
identified
assessed
against
four
predefined
dimensions
effectiveness,
applicability,
scalability
cost-effectiveness.
lowest
scores
obtained
within
last
these
categories,
unavailability
relevant
data.
Based
results,
application
constructed.
allows
comparing
individual
program
ones,
particularly,
national
context.
Conclusion:
By
strong
evidence,
findings
study,
coupled
application,
can
prove
valuable
aiding
clinicians
policymakers
implementation
expansion
elderly.
Arboriculture & Urban Forestry,
Journal Year:
2025,
Volume and Issue:
unknown, P. jauf.2025.006 - jauf.2025.006
Published: Feb. 10, 2025
Abstract
Background
Hawai‘i’s
exceptional
trees
are
currently
identified
based
on
7
selection
criteria
established
in
1975.
These
and
their
corresponding
program
components
have
remained
stagnant
with
minimal
improvements
since
the
program’s
inception.
This
study
builds
upon
previous
(aka
“heritage,”
“significant,”
“champion,”
“monumental,”
“notable,”
etc.)
tree
research
conducted
other
geographic
locations
an
attempt
to
discover
if
consensus
exists
regarding
how
these
of
importance
should
be
identified,
managed,
protected.
Methods
A
panel
13
experts
from
around
state
were
presented
45
several
using
a
3-iteration
Delphi
method
determine
which
used
by
Exceptional
Tree
Program.
Results
The
results
33
5
(i.e.,
protection
mechanisms,
private
property
maintenance
costs,
funding,
public
education
outreach,
management
best
practices)
recommended
expert
panel,
as
well
examples
each
implemented
improve
efficacy
this
conservation
program.
Conclusions
findings
add
growing
body
designed
identify,
recognize,
protect
region’s
most
valued
trees,
while
also
having
applicability
urban
forestry
programs
more
broadly.
Palliative Medicine,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 15, 2025
Background:
Off-label
use
of
drugs
is
an
integral
part
everyday
clinical
practice
in
palliative
medicine.
However,
it
associated
with
many
uncertainties,
that
is,
drug
therapy
safety
or
legal
issues
including
cost
coverage.
Healthcare
professionals
often
lack
time
and
resources
for
comprehensive
literature
search
patient-specific
risk-benefit
analyses.
Aim:
The
aim
this
project
to
develop,
evaluate
rate
agreement/disagreement
on
treatment
recommendations
off-label
adult
Design:
Online
Delphi
study
two
rounds
each
An
international
expert
panel
consisting
physicians,
pharmacists
nurses
working
care
evaluated
previously
developed
based
the
best
available
evidence.
Setting:/participants:
Professionals
(physicians,
pharmacists,
nursing
staff)
inpatient
home
involved
medication
process
were
recruited
as
experts
participate.
Between
64
75
participated
first
studies.
Results:
A
total
64/68
21
14
applications
agreed
upon.
Topics
related
routes
administration
well
indications
sialorrhea,
bronchorrhea,
xerostomia,
pruritus,
singultus,
fistula,
gastroparesis
hot
flashes.
Recommendations
reached
consensus
are
health
via
a
free
charge
database.
Conclusion:
For
applications,
likely
there
will
be
no
registration
studies
therefore
approvals
future.
consensus-based
intended
facilitate
individual
planning
prescribers
enable
more
reflected
handling
use.
SAGE Open,
Journal Year:
2022,
Volume and Issue:
12(4)
Published: Oct. 1, 2022
In
today’s
world,
Global
Competence
represents
a
fundamental
disposition
for
teachers
who
must
be
able
to
teach
effectively
in
classrooms
with
students
from
diverse
backgrounds
and
manage
multiple
learning
contexts.
For
these
reasons,
it
is
necessary
set
up
educational
activities
during
initial
teacher
education
programs
aimed
at
developing
assessing
preservice
teachers’
ability
Competent.
This
study
was
designing
creating
of
rubrics
that
can
used
by
either
educators
or
teachers,
this
case,
as
self-assessment
instrument.
The
research
design
based
on
modified
Delphi
method
composed
five
rounds
collect
both
qualitative
quantitative
data.
A
panel
31
experts
involved
an
iterative
process
until
consensus
among
the
reached.
employed
several
contexts
situations
such
as:
before
after
international
experience,
simulation
workshop
intercultural
real-world
situations.
International Journal of Behavioral Nutrition and Physical Activity,
Journal Year:
2023,
Volume and Issue:
20(1)
Published: July 25, 2023
Abstract
Background
Despite
significant
interest
in
assessing
activity
patterns
different
populations,
there
has
been
no
consensus
concerning
the
definition
and
operationalisation
of
this
term.
This
limited
comparability,
interpretability,
synthesis
study
findings
to
date.
The
aim
was
establish
a
regarding
way
which
pattern
components
are
defined
reported.
Methods
literature
searched
identify
experts
be
invited
participate
develop
proposed
components.
A
three-round
modified
Delphi
survey
conducted
online
(November
2021
May
2022).
In
Round
1,
participants
were
asked
rate
their
agreement
with
definition,
also
included
six
(e.g.,
intensity,
bout,
transitions),
examples
frequency
postural
transitions
discrete
time
periods)
eight
items
for
reporting
future
research
(n
=
21
items).
Open-ended
questions
enabled
provide
further
comments
suggestions
additional
items.
Consensus
priori
as
≥
80%
rating
an
item.
2,
25
(13
original
items,
amended,
four
new).
3,
rated
10
(five
one
Results
Twenty
participated
response
rates
60%
Rounds
2
respectively.
all
definitions,
examples,
framework
achieved
consensus.
removal
component
item
between
1
Conclusion
defining
first
time.
enables
standardisation
terminology,
is
important
given
quantifying
how
individuals
accumulate
physical
sedentary
behaviour
across
lifespan
inform
development
public
health
guidelines
interventions
efforts.
Future Oncology,
Journal Year:
2023,
Volume and Issue:
19(11), P. 763 - 773
Published: April 1, 2023
Aim:
To
define
ruxolitinib
failure
and
develop
parameters
to
guide
transition
next-line
therapy
for
patients
with
myelofibrosis.
Methods:
A
modified
Delphi
panel
14
hematologists-oncologists.
Survey
concepts
included
defining
primary
refractory
status,
loss
of
response,
disease
progression,
intolerance
therapy.
Results:
Ruxolitinib
may
be
defined
as
no
improvement
in
symptoms
or
spleen
size,
progressive
intolerance,
following
a
maximally
tolerated
dose
≥3
months.
Loss
response
1
month
after
initial
prompt
discontinuation.
Lack
evidence
inform
was
noted;
tapering
should
considered
according
patient
characteristics.
Conclusion:
Expert
consensus
provided
on
summarized
this
position
paper,
which
support
considerations
the
development
future
clinical
practice
guidelines.People
myelofibrosis
who
receive
treatment
need
stop
because
it
is
not
working
they
cannot
tolerate
side
effects.
There
little
good
scientific
information
available
about
how
when
treatment,
move
another
stopping
ruxolitinib.
group
experts
hematology
oncology
followed
process,
called
method,
discuss
topic
reach
agreement
most
important
aspects
challenge.
The
agreed
that
having
receiving
highest
could
results
expert
discussion
their
healthcare
providers
making
decisions
real
life,
guidelines.
Vilakshan – XIMB Journal of Management,
Journal Year:
2020,
Volume and Issue:
17(1/2), P. 79 - 95
Published: Oct. 12, 2020
Purpose
Start-ups
are
the
new
avenues
for
innovation
and
employment.
Strategic
management
is
critical
employee
engagement
skill
development
of
start-ups.
This
study
aims
to
understand
impact
strategic
on
development.
Design/methodology/approach
The
attempts
identify
principal
factors
influencing
Structural
equation
modeling
has
been
used
effects
study.
Findings
results
have
shown
challenges
concerning
reflected
importance
programmes
growth
human
resource
in
Research
limitations/implications
confined
However,
studies
related
encountered
by
start-ups
specific
areas
marketing,
operations
finance,
etc.
would
provide
more
detailed
Practical
implications
provides
an
insight
into
directions
improving
strategy
from
perspective
Social
a
direction
owners
building
strong
enterprising
which
can
employment
opportunity
youth
nation
improve
society
at
large.
Originality/value
paper
attempt
managing
employees’
development,
essential
sustainability
future.
Translational Behavioral Medicine,
Journal Year:
2020,
Volume and Issue:
11(2), P. 642 - 652
Published: March 7, 2020
Abstract
Poor
health
behaviors
(e.g.,
smoking,
poor
diet,
and
physical
inactivity)
are
major
risk
factors
for
noncommunicable
chronic
diseases
(NCDs).
Evidence
supporting
traditional
advice-giving
approaches
to
promote
behavior
change
is
weak
or
short
lived.
Training
physicians
improve
their
counseling/communication
skills
important,
yet
the
evidence
efficacy
acceptability
of
existing
training
programs
lacking
there
little
consensus
on
core
competencies
that
should
master
in
context
NCD
management.
The
purpose
this
study
generate
an
acceptable,
evidence-based,
stakeholder-informed
list
communication
Using
a
modified
Delphi
process
achievement,
international
experts,
physicians,
allied
care
professionals
completed
four
phases
research,
including
eight
rounds
online
surveys
in-person
meetings
over
2
years
(n
=
13–17
participated
Phases
I,
III,
IV
n
39–46
Phase
II).
Eleven
were
identified:
reflective
listening,
expressing
empathy,
demonstrating
acceptance,
tolerance,
respect,
responding
resistance,
(not)
negatively
judging
blaming,
hostility
impatience,
eliciting
“change-talk”/evocation,
being
argumentative
confrontational,
setting
goals,
collaborative,
providing
information
neutrally.
These
used
define
unified
approach
conducting
counseling
medical
settings:
Motivational
Communication.
results
may
be
inform
standardize
physician
reduce
morbidity
mortality
related
prevention
International Journal of Drug Policy,
Journal Year:
2022,
Volume and Issue:
106, P. 103768 - 103768
Published: June 16, 2022
Emergency
contingency
guidelines
for
opioid
agonist
treatment
(OAT)
were
introduced
in
Ireland
March
2020,
to
ensure
rapid
and
uninterrupted
access
while
mitigating
COVID-19
risk.
The
deviated,
across
multiple
clinical
domains,
from
pre-pandemic
published
2016.
objectives
of
this
study
are
(1)
identify
changes
OAT
during
the
pandemic;
(2)
develop
consensus
on
whether
new
recommendations
should
be
retained
beyond
pandemic,
using
a
national
Delphi
methodology.
Clinical
guidance
('statements')
generated
by
comparing
newly
established
with
2016
Guidelines
OAT.
Over
two
rounds
on-line
testing,
panel
experts
(people
currently
accessing
OAT,
psychiatrists,
general
practitioners,
community
pharmacists,
nurse,
psychologist
support/key
workers)
independently
rated
their
agreement
each
statement
provided
comments.
Statements
median
score
4
or
5
lower
quartile
≥4
classified
as
having
reached
consensus.
Forty-eight
members
recruited,
high
participation
level
at
Round
2
(90%,
n=43).
Consensus
was
achieved
12
19
statements
1.
7
remaining
revised,
statements,
resulting
9
2.
Four
final
list
includes
16
statements;
relating
assessment,
3
drug
choice
dosing,
1
take-away
doses,
overdose
prevention
continuation
e-prescriptions.
A
wide
range
stakeholders
involved
delivery
receipt
agreed
inclusion
we
move
rather
than
reverting
guidelines.
relate
facilitating
safe
minimal
waiting
time,
supporting
patient-centred
care
promote
health
well-being,
preventing
overdose.
Notably,
not
dosage
frequency
urine
testing
stabilisation
maintenance
phase
care.