The mystery of claustral neural circuits and recent updates on its role in neurodegenerative pathology
Behavioral and Brain Functions,
Journal Year:
2021,
Volume and Issue:
17(1)
Published: July 7, 2021
The
claustrum
is
a
structure
involved
in
formation
of
several
cortical
and
subcortical
neural
microcircuits
which
may
be
such
functions
as
conscious
sensations
rewarding
behavior.
regarded
multi-modal
information
processing
network.
Pathology
the
seen
certain
neurological
disorders.
To
date,
there
are
not
enough
comprehensive
studies
that
contain
accurate
regarding
involvement
development
Language: Английский
Insula activity in resting-state differentiates bipolar from unipolar depression: a systematic review and meta-analysis
Martin Paštrnák,
No information about this author
Eva Šimková,
No information about this author
Tomáš Novák
No information about this author
et al.
Scientific Reports,
Journal Year:
2021,
Volume and Issue:
11(1)
Published: Aug. 20, 2021
Symptomatic
overlap
of
depressive
episodes
in
bipolar
disorder
(BD)
and
major
(MDD)
is
a
diagnostic
therapeutic
problem.
Mania
medical
history
remains
the
only
reliable
distinguishing
marker
which
problematic
given
that
depression
compared
to
mania
are
more
frequent
predominantly
present
at
beginning
BD.
Resting-state
functional
magnetic
resonance
imaging
(rs-fMRI)
non-invasive,
task-free,
well-tolerated
method
may
provide
markers
acquired
from
spontaneous
neural
activity.
Previous
rs-fMRI
studies
focused
on
differentiating
BD
MDD
were
inconsistent
their
findings
due
low
sample
power,
heterogeneity
samples,
diversity
analytical
methods.
This
meta-analysis
investigated
resting-state
activity
differences
using
activation
likelihood
estimation.
PubMed,
Web
Science,
Scopus
Google
Scholar
databases
searched
for
whole-brain
currently
depressed
patients
between
Jan
2000
August
2020.
Ten
included,
representing
234
296
patients.
The
found
increased
left
insula
adjacent
area
finding
suggests
involved
patterns
during
can
be
potentially
used
as
biomarker
both
disorders.
Language: Английский
The Role of the Claustrum in Parkinson’s Disease and Vascular Parkinsonism: A Matter of Network?
Marialuisa Zedde,
No information about this author
R. Quatrale,
No information about this author
Gianni Cossu
No information about this author
et al.
Life,
Journal Year:
2025,
Volume and Issue:
15(2), P. 180 - 180
Published: Jan. 26, 2025
Background:
The
mechanisms
underlying
extrapyramidal
disorders
and
their
anatomical
substrate
have
been
extensively
investigated.
Recently,
the
role
of
claustrum
in
Parkinson’s
disease
other
neurodegenerative
conditions
has
better
detailed.
main
aim
this
review
was
to
summarize
supporting
evidence
for
degenerative
vascular
parkinsonism.
Methods:
anatomy,
biology,
supply,
connections
humans
were
identified
described,
providing
involvement
large-
small-vessel
disease.
supply
includes
up
three
different
sources
from
a
single
artery,
middle
cerebral
it
is
known
as
territory
with
an
intermediate
hemodynamic
risk.
make
sensory
integrator
relevant
point
several
networks,
consciousness
movement
planning.
Conclusions:
still
incompletely
explained
structure.
However,
recent
description
its
multiple
indicate
that
involved
diseases,
including
potential
parkinsonism
scarce,
but
might
be
field
warranting
future
investigations.
Language: Английский
Adult‐onset epilepsy with startle‐induced seizure after febrile infection‐related epilepsy syndrome: A case report
Epileptic Disorders,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 15, 2025
Abstract
Startle‐induced
seizure
is
a
rare
type
of
reflex
triggered
by
unexpected
sensory
stimuli
that
often
occurs
in
children
with
early
acquired
cerebral
lesions
or
brain
malformations.
We
report
unique
case
adult‐onset
epilepsy
startle‐induced
seizures.
A
24‐year‐old
woman
had
suffered
high
fever
and
focal
to
bilateral
tonic–clonic
diagnosis
febrile
infection‐related
syndrome
(FIRES)
was
made
based
on
the
infection
occurring
7
days
24
h
before
onset
status
epilepticus,
which
met
all
criteria
for
cryptogenic
new‐onset
refractory
epilepticus
(NORSE)
according
NORSE
score.
Immunotherapy
several
antiseizure
medications
resulted
transient
resolution
Four
months
later,
she
experienced
seizures
stimuli,
such
as
auditory,
visual,
events,
manifesting
initial
tachycardia
followed
right
ear
deafness,
hemifacial
dysesthesia,
eye
deviation
right,
convulsions.
Ictal
electroencephalography
revealed
left
temporal
rhythmic
delta
activity,
theta
activity.
The
patient
diagnosed
startle
associated
FIRES
continued
receive
anti‐seizure
medications.
Claustrum‐insular‐operculum
may
have
been
epileptic
focus
this
case,
contrast
previous
cases
originating
frontoparietal
network.
This
indicates
new
category
post‐FIRES
Language: Английский
Resting State Functional Connectivity of the Marmoset Claustrum
Erin J. Holzscherer,
No information about this author
Alessandro Zanini,
No information about this author
Chun Yin Liu
No information about this author
et al.
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 29, 2025
Abstract
The
common
marmoset
(Callithrix
jacchus)
has
been
recently
developed
as
a
nonhuman
primate
model
useful
for
studying
behaviour,
neurology,
and
higher-level
cognitive
processes
considering
their
phylogenetic
proximity
to
humans.
Here,
we
investigated
the
resting
state
functional
connectivity
(RSFC)
of
claustrum,
small,
highly
connected
subcortical
structure.
Using
an
open
resource
234
MRI
scans
from
awake
marmosets,
found
claustrum
prefrontal
cortex,
posterior
parietal
temporal
cortices,
cingulate
sensory
limbic
areas,
basal
ganglia,
cerebellum.
We
also
strong
regions
hubs
involved
in
networks.
These
findings
demonstrate
RSFC
similar
previous
human
rodent
studies
validate
integration
marmosets
into
research.
Language: Английский
Changing the Cortical Conductor’s Tempo: Neuromodulation of the Claustrum
Frontiers in Neural Circuits,
Journal Year:
2021,
Volume and Issue:
15
Published: May 13, 2021
The
claustrum
is
a
thin
sheet
of
neurons
that
densely
connected
to
many
cortical
regions
and
has
been
implicated
in
numerous
high-order
brain
functions.
Such
functions
arise
from
states
are
influenced
by
neuromodulatory
pathways
the
cholinergic
basal
forebrain,
dopaminergic
substantia
nigra
ventral
tegmental
area,
serotonergic
raphe.
Recent
revelations
receives
dense
input
these
structures
have
inspired
investigation
state-dependent
control
claustrum.
Here,
we
review
neuromodulation
claustrum-from
anatomical
connectivity
behavioral
manipulations-to
inform
future
analyses
claustral
function.
Language: Английский
Differentiation of claustrum resting‐state functional connectivity in healthy aging, Alzheimer's disease, and Parkinson's disease
Human Brain Mapping,
Journal Year:
2022,
Volume and Issue:
44(4), P. 1741 - 1750
Published: Dec. 14, 2022
The
claustrum
is
a
sheet-like
of
telencephalic
gray
matter
structure
whose
function
poorly
understood.
considered
multimodal
computing
network
due
to
its
reciprocal
connections
with
almost
all
cortical
areas
as
well
subcortical
structures.
Although
the
has
been
involved
in
several
neurodegenerative
diseases,
specific
changes
remain
unclear
Alzheimer's
disease
(AD),
and
Parkinson's
(PD).
Resting-state
fMRI
T1-weighted
structural
3D
images
from
healthy
elderly
(n
=
15),
AD
16),
PD
12)
subjects
were
analyzed.
Seed-based
FC
analysis
was
performed
using
CONN
toolbox
analyzed
Computational
Anatomy
Toolbox
for
voxel-based
morphometry
analysis.
While
we
observed
decreased
between
left
sensorimotor
cortex,
auditory
association
regions
associated
social
cognition
compared
control
group
(HC),
no
significant
difference
found
alterations
both
comparing
HC
groups.
In
group,
high
cortex
related
cognitive
control,
including
cingulate
gyrus,
supramarginal
insular
demonstrated.
addition,
results
show
significantly
volume
bilateral
HC.
There
differences
volumes
groups
so
may
offer
more
precise
findings
distinguishing
PD.
Language: Английский
Artificial Intelligence-Assisted Evaluation of English Teaching Effectiveness in Colleges and Universities
Applied Mathematics and Nonlinear Sciences,
Journal Year:
2024,
Volume and Issue:
9(1)
Published: Jan. 1, 2024
Abstract
Education
informatization
is
an
important
initiative
for
the
country
to
realize
education
modernization,
which
related
development
of
China’s
education.
The
use
a
single
evaluation
teaching
effectiveness
obviously
cannot
meet
assessment
needs.
Based
on
premise
intelligent
assistance
through
hybrid
brain-computer
interface,
this
paper
aims
study
method
using
artificial
intelligence.
Firstly,
EEG
signals
are
collected
acquisition
device,
and
then
they
preprocessed.
Second,
pre-processed
subjected
feature
extraction,
features
classified
specific
pattern
recognition
method,
finally
classification
results
used
assess
English
college
students.
results,
learning
system
optimized
improved.
by
devices
carry
lot
noise,
in
paper,
processing
original
includes
smoothing
filter,
de-baseline
filter
Kalman
achieve
higher
signal-to-noise
ratio.
Multivariate
provided
that
assisted
Compared
with
other
methods
enrich
information,
based
above
study,
as
far
F1
value
concerned,
paper’s
highest,
reaching
0.815,
0.048
than
highest
traditional
algorithm,
two
values,
also
methods.
This
verifies
rationality
interface
proposed
paper.
Language: Английский