Polyphenols and Microbiota Modulation: Insights from Swine and Other Animal Models for Human Therapeutic Strategies DOI Creative Commons

Andrei Cristian Anghel,

Ionelia Țăranu, Alina Orțan

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(24), P. 6026 - 6026

Published: Dec. 20, 2024

High consumption of ultra-processed foods, rich in sugar and unhealthy fats, has been linked to the onset numerous chronic diseases. Consequently, there a growing shift towards fiber-rich diet, abundant fruits, vegetables, seeds, nuts, enhance longevity quality life. The primary bioactive components these plant-based foods are polyphenols, which exert significant effects on modulating gastrointestinal microbiota through their antioxidant anti-inflammatory activities. This modulation preventive neurodegenerative, metabolic, cardiovascular diseases, even cancer. antimicrobial properties polyphenols against pathogenic bacteria have significantly reduced need for antibiotics, thereby lowering risk antibiotic resistance. paper advances field by offering novel insights into beneficial both directly metabolites produced during digestion indirectly changes host’s microbiota, uniquely emphasizing swine as model highly relevant human health, topic that, our knowledge, not thoroughly explored previous reviews. review also addresses aspects related other animal models (mice, rabbits, rats), humans, providing guidelines future research benefits polyphenol consumption. By linking agricultural biomedical perspectives, it proposes strategies utilizing compounds therapeutic agents veterinary health sciences.

Language: Английский

Polyphenols and Microbiota Modulation: Insights from Swine and Other Animal Models for Human Therapeutic Strategies DOI Creative Commons

Andrei Cristian Anghel,

Ionelia Țăranu, Alina Orțan

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(24), P. 6026 - 6026

Published: Dec. 20, 2024

High consumption of ultra-processed foods, rich in sugar and unhealthy fats, has been linked to the onset numerous chronic diseases. Consequently, there a growing shift towards fiber-rich diet, abundant fruits, vegetables, seeds, nuts, enhance longevity quality life. The primary bioactive components these plant-based foods are polyphenols, which exert significant effects on modulating gastrointestinal microbiota through their antioxidant anti-inflammatory activities. This modulation preventive neurodegenerative, metabolic, cardiovascular diseases, even cancer. antimicrobial properties polyphenols against pathogenic bacteria have significantly reduced need for antibiotics, thereby lowering risk antibiotic resistance. paper advances field by offering novel insights into beneficial both directly metabolites produced during digestion indirectly changes host’s microbiota, uniquely emphasizing swine as model highly relevant human health, topic that, our knowledge, not thoroughly explored previous reviews. review also addresses aspects related other animal models (mice, rabbits, rats), humans, providing guidelines future research benefits polyphenol consumption. By linking agricultural biomedical perspectives, it proposes strategies utilizing compounds therapeutic agents veterinary health sciences.

Language: Английский

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