Trends of respiratory viruses and factors associated with severe acute respiratory infection in patients presenting at a university hospital: a 6-year retrospective study across the COVID-19 pandemic

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: March 28, 2025

The COVID-19 pandemic significantly disrupted the epidemiology of respiratory viruses, altering seasonal patterns and reducing circulation. While recovery trends have been observed, factors associated with severe acute infections (SARIs) during pre- post-pandemic periods remain underexplored in middle-income countries. This study aimed to analyze virus circulation identify SARI patients attending a tertiary care university hospital western Mexico over six-year period spanning pre-pandemic, pandemic, phases. A retrospective was conducted using data from 19,088 symptomatic tested for viruses between 2018 2024. Viral were analyzed through interrupted time series (ITS) modeling, incorporating locally estimated scatterplot smoothing (LOESS) raw positivity rates. Additionally, ITS analysis performed evaluate temporal changes proportions across different phases pandemic. Multivariate logistic regression models applied determine independent risk periods. During (2020-2021), rates declined, particularly influenza, which experienced sharp reduction but rebounded post-2022. Respiratory syncytial (RSV) demonstrated delayed resurgence, whereas other exhibited heterogeneous rebound patterns. modeling revealed significant pre-pandemic increasing trend, followed by slower rise drop early 2022, before resuming an upward trajectory. Among older adults (>65 years), marked increase observed at beginning while younger groups showed more stable Logistic identified advanced age, male sex, cardiovascular disease, obesity, immunosuppression as major SARI, vaccination consistently protective effect all subgroups. induced persistent shifts circulation, disrupting dynamics modifying burden SARI. findings underscore importance continuous surveillance, targeted programs, diagnostics mitigate outcomes. These results highlight need adaptive public health strategies countries address evolving disease threats.

Language: Английский

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The changing landscape of pediatric infectious diseases before, during, and after the COVID-19 pandemic

Child Health Nursing Research, Journal Year: 2025, Volume and Issue: 31(2), P. 79 - 84

Published: April 30, 2025

Language: Английский

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Prevalence of Co-Infections in Primary Care Patients with Medically Attended Acute Respiratory Infection in the 2022/2023 Season

Viruses, Journal Year: 2024, Volume and Issue: 16(8), P. 1289 - 1289

Published: Aug. 13, 2024

In the post-pandemic period, an endemic circulation of respiratory viruses has been re-established. Respiratory are co-circulating with SARS-CoV-2. We performed a retrospective analysis co-infections in primary care patients medically attended acute infections (MAARI) who consulted from week 40/2022 to 39/2023 and were tested for panel viruses. Out 2099 samples tested, 1260 (60.0%) positive one virus. 340 samples, co-infection was detected: two 281 (13.4%), three 51 (2.4%), four eight (0.4%) samples. co-infected MAARI at very different rates. The lowest rates confirmed influenza B (13.8%) A (22.9%) highest human bocaviruses (84.0%) parechoviruses (82.1%). Co-infections detected 28.2% SARS-CoV-2 never virus, enterovirus or adenovirus, although latter found as co-infecting virus all other tested. rate decreased significantly increasing age (p-value 0.000), no difference regarding gender 0.672). It is important understand epidemiology prevention management decisions MAARI.

Language: Английский

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Seasonal Shifts in Influenza, Respiratory Syncytial Virus, and Other Respiratory Viruses After the COVID-19 Pandemic: An Eight-Year Retrospective Study in Jalisco, Mexico

Viruses, Journal Year: 2024, Volume and Issue: 16(12), P. 1892 - 1892

Published: Dec. 8, 2024

The coronavirus disease 2019 (COVID-19) pandemic profoundly disrupted the epidemiology of respiratory viruses, driven primarily by widespread non-pharmaceutical interventions (NPIs) such as social distancing and masking. This eight-year retrospective study examines seasonal patterns incidence influenza virus, syncytial virus (RSV), other viruses across pre-pandemic, pandemic, post-pandemic phases in Jalisco, Mexico. Weekly case counts were analyzed using an interrupted time series (ITS) model, segmenting timeline into these three distinct phases. Significant reductions circulation observed during followed atypical resurgences NPIs relaxed. Influenza displayed alternating subtype dominance, with A H3 prevailing 2022, B surging 2023, H1N1 increasing thereafter, reflecting potential immunity gaps. RSV activity was marked earlier onset higher intensity post-pandemic. Other including human rhinovirus/enterovirus (HRV/HEV) parainfluenza (HPIV), showed altered dynamics, some failing to return pre-pandemic seasonality. These findings underscore need for adaptive surveillance systems vaccination strategies address evolving viral patterns. Future research should investigate long-term public health implications, focusing on vaccination, clinical outcomes, healthcare preparedness.

Language: Английский

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Respiratory pathogen dynamics in community fever cases: Jiangsu Province, China (2023–2024)

Virology Journal, Journal Year: 2024, Volume and Issue: 21(1)

Published: Sept. 20, 2024

Respiratory infectious diseases have the highest incidence among worldwide. Currently, global monitoring of respiratory pathogens primarily focuses on influenza and coronaviruses. This study included other common to establish a local pathogen spectrum. We investigated analyzed co-infection patterns these explored impact lifting non-pharmaceutical interventions (NPIs) transmission pathogens. Additionally, we used predictive model for diseases, utilizing commonly An autoregressive comprehensive moving average (ARIMA), which can effectively forecast disease incidence.

Language: Английский

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