Molecular Aspects of Inflammation and Lipid Metabolism in Health and Disease: The Role of the Mitochondria
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(12), P. 6299 - 6299
Published: June 7, 2024
Inflammation
and
lipid
metabolism
are
two
deeply
interconnected
reciprocally
regulated
major
physiological
processes
[...].
Language: Английский
Role of mitochondria in inflammatory lung diseases
Frontiers in Pharmacology,
Journal Year:
2024,
Volume and Issue:
15
Published: Aug. 20, 2024
Mitochondria
play
a
significant
and
varied
role
in
inflammatory
lung
disorders.
Mitochondria,
known
as
the
powerhouse
of
cell
because
their
producing
energy,
are
now
recognized
crucial
regulators
inflammation
immunological
responses.
Asthma,
chronic
obstructive
pulmonary
disease,
acute
respiratory
distress
syndrome
characterized
by
complex
interactions
between
immune
cells,
substances,
tissue
damage.
Dysfunctional
mitochondria
can
increase
generation
reactive
oxygen
species
(ROS),
triggering
pathways.
Moreover,
mitochondrial
failure
impacts
cellular
signaling,
which
turn
affects
expression
molecules
that
promote
inflammation.
In
addition,
have
controlling
behavior
such
activation
differentiation,
is
essential
development
diseases.
Their
dynamic
behavior,
encompassing
fusion,
fission,
mitophagy,
also
responses
to
oxidative
stress.
Gaining
comprehensive
understanding
intricate
correlation
order
develop
accurate
treatment
strategies.
Targeting
ROS
generation,
dynamics,
function
may
offer
novel
approaches
treating
diseases
while
minimizing
Additional
investigation
into
precise
contributions
will
provide
knowledge
regarding
disease
mechanisms
potential
therapeutic
approaches.
This
review
focus
on
how
regulate
these
processes
involvement
Language: Английский
The role of NRF2 function and regulation in atherosclerosis: an update
Molecular and Cellular Biochemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 1, 2025
Language: Английский
The role and therapeutic potential of mitophagy in major depressive disorder
Xiulin Shi,
No information about this author
Chenyue Liu,
No information about this author
Li Lin
No information about this author
et al.
Frontiers in Pharmacology,
Journal Year:
2025,
Volume and Issue:
16
Published: March 26, 2025
Major
depressive
disorder,
also
known
as
MDD,
affects
more
than
264
million
people
globally,
making
it
a
prevalent
and
critical
health
challenge.
Traditional
treatments
show
limited
efficacy
in
many
patients.
Therefore,
exploring
new
treatment
methods
is
particularly
crucial.
Mitophagy,
regulatory
process,
can
help
understand
treat
MDD.
This
paper
focuses
on
the
molecular
mechanisms
of
mitophagy,
starting
from
proteins
related
pathways,
its
role
The
study
explores
associations
between
mitophagy
neuroinflammation,
oxidative
stress,
neurotransmitter
synthesis,
neuroplasticity
MDD
discusses
progress
clinical
research
In
addition,
article
describes
current
pharmaceutical
non-pharmaceutical
interventions
that
regulate
unravels
potential
challenges
these
therapeutic
strategies
settings.
offers
deeper
insight
into
pathogenesis
scientific
basis
for
development
strategies.
Language: Английский
Preclinical and mechanistic perspectives on adipose-derived stem cells for atherosclerotic cardiovascular disease treatment
Molecular and Cellular Biochemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 16, 2025
Language: Английский
The role of Epsins in atherosclerosis: From molecular mechanisms to therapeutic applications
Vascular Pharmacology,
Journal Year:
2024,
Volume and Issue:
158, P. 107457 - 107457
Published: Dec. 11, 2024
Language: Английский
Effects of prolonged NaHCO3 exposure on the serum immune function, antioxidant capacity, intestinal tight junctions, microbiota, mitochondria, and autophagy in crucian carp (Carassius auratus)
Jia Liu,
No information about this author
Faye Zhang,
No information about this author
Zihao Yan
No information about this author
et al.
Ecotoxicology and Environmental Safety,
Journal Year:
2024,
Volume and Issue:
290, P. 117571 - 117571
Published: Dec. 20, 2024
Language: Английский