Neurotoxic chemistry: Unraveling the chemical mechanisms connecting environmental toxin exposure to neurological disorders

Journal of Integrated Science and Technology, Journal Year: 2025, Volume and Issue: 13(3)

Published: Jan. 7, 2025

The environmental pollution poses a serious global health risk, contributing to high morbidity and mortality rates. Neurological disorders, such as Alzheimer's, Parkinson's, Schizophrenia, ALS, Huntington's disease, are increasingly prevalent characterized by both structural functional abnormalities in neurons of the brain spinal cord. Understanding neuro-impact toxins is crucial for developing effective prevention intervention strategies. This review article investigates complex interactions between neurological health, focusing on their role development progression neurodegenerative neuropsychiatric disorders. Key mechanisms include oxidative stress, mitochondrial dysfunction, and, disruption neurotransmitter systems. It highlights pathways through which these exert effects, presents epidemiological evidence linking toxin exposure discusses potential public implications. By elucidating connections, paper aims enhance understanding determinants health.

Language: Английский

Phytomolecules as Alzheimer’s Therapeutics: A Comprehensive Review

European Journal of Medicinal Chemistry, Journal Year: 2025, Volume and Issue: 288, P. 117401 - 117401

Published: Feb. 18, 2025

Language: Английский

Ferroptosis and Cognitive Impairment: Unraveling the Link and Potential Therapeutic Targets

Neuropharmacology, Journal Year: 2024, Volume and Issue: 263, P. 110210 - 110210

Published: Nov. 7, 2024

Language: Английский