Edge advances in nanodrug therapies for osteoarthritis treatment DOI Creative Commons
Jinfeng Liao, Qinxuan Gu,

Zheng Liu

et al.

Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15

Published: Oct. 30, 2024

As global population and lifestyles change, osteoarthritis (OA) is becoming a major healthcare challenge world. OA, chronic condition characterized by inflammatory degeneration, often present with joint pain can lead to irreversible disability. While there currently no cure for it commonly managed using nonsteroidal anti-inflammatory drugs (NSAIDs), glucocorticoids, glucosamine. Although these treatments alleviate symptoms, difficult effectively deliver sustain therapeutic agents within joints. The emergence of nanotechnology, particularly in form smart nanomedicine, has introduced innovative approaches OA treatment. Nanotherapeutic strategies offer promising advantages, including more precise targeting affected areas, prolonged effects, enhanced bioavailability, reduced systemic toxicity compared traditional treatments. nanoparticles show potential as viable delivery system therapies based on encouraging lab-based clinical trials results, remails considerable gap between current research application. This review highlights recent advances nanotherapy explore future pathways refine optimize strategies.

Language: Английский

Edge advances in nanodrug therapies for osteoarthritis treatment DOI Creative Commons
Jinfeng Liao, Qinxuan Gu,

Zheng Liu

et al.

Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15

Published: Oct. 30, 2024

As global population and lifestyles change, osteoarthritis (OA) is becoming a major healthcare challenge world. OA, chronic condition characterized by inflammatory degeneration, often present with joint pain can lead to irreversible disability. While there currently no cure for it commonly managed using nonsteroidal anti-inflammatory drugs (NSAIDs), glucocorticoids, glucosamine. Although these treatments alleviate symptoms, difficult effectively deliver sustain therapeutic agents within joints. The emergence of nanotechnology, particularly in form smart nanomedicine, has introduced innovative approaches OA treatment. Nanotherapeutic strategies offer promising advantages, including more precise targeting affected areas, prolonged effects, enhanced bioavailability, reduced systemic toxicity compared traditional treatments. nanoparticles show potential as viable delivery system therapies based on encouraging lab-based clinical trials results, remails considerable gap between current research application. This review highlights recent advances nanotherapy explore future pathways refine optimize strategies.

Language: Английский

Citations

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