Direct-to-Consumer Testing: Benefits and Concerns of Commercially Accessed Laboratory Tests
Clinical Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 18, 2025
Abstract
Background
Promoting
self-empowerment
of
patients
and
healthy
persons
in
contemporary
health
cultures
shifts
the
imperative
for
initiating
laboratory
tests
from
healthcare
professionals
(HCP)
to
themselves.
Content
Laboratory
testing
requested
directly
by
without
interaction
HCP
is
called
DTCT
(direct-to-consumer
testing).
not
conducted
within
traditional
systems,
regulations
that
protect
are
necessarily
present
DTCT.
Aggressive
marketing
may
mislead
consumer,
resulting
psychological,
physical,
financial
harm.
The
benefit
dependent
on
being
used
selected
persons,
with
samples
collected
stored
appropriately,
measured
an
adequate
technique
test
results
interpreted
properly.
can
empower
patients,
but
consumer
knowledge
varies
currently,
there
a
lack
reliable
resources
consumers
consult.
In
absence
protection
rules
DTCT,
concept
informing
concurrently
vendors
place.
Summary
might
be
advantageous
over
settings
few
situations
has
substantial
risk
medicalization
damaging
trust
reliability
testing.
Language: Английский
New insights in preanalytical quality
Clinical Chemistry and Laboratory Medicine (CCLM),
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 23, 2025
Abstract
The
negative
impact
of
preanalytical
errors
on
the
quality
laboratory
testing
is
now
universally
recognized.
Nonetheless,
recent
technological
advancements
and
organizational
transformations
in
healthcare
–
catalyzed
by
still
ongoing
coronavirus
disease
2019
(COVID-19
pandemic)
have
introduced
new
challenges
promising
opportunities
for
improvement.
integration
value-based
scoring
systems
clinical
laboratories
growing
evidence
linking
to
patient
outcomes
costs
underscore
critical
importance
this
phase.
Emerging
topics
phase
include
pursuit
a
“greener”
more
sustainable
environment,
innovations
self-sampling
automated
blood
collection,
strategies
minimize
loss.
Additionally,
efforts
reduce
enhance
sustainability
through
management
gained
momentum.
Digitalization
artificial
intelligence
(AI)
offer
transformative
potential,
with
applications
sample
labeling,
recording
collection
events,
monitoring
conditions
during
transportation.
AI-driven
tools
can
also
streamline
workflow
mitigate
errors.
Specific
managing
hemolysis
developing
its
impact,
addressing
issues
related
urine
designing
robust
protocols
stability
studies.
rise
decentralized
presents
unique
hurdles,
while
emerging
areas
such
as
liquid
biopsy
anti-doping
introduce
novel
complexities.
Altogether,
these
highlight
dynamic
evolution
need
continuous
innovation
standardization.
This
collective
opinion
paper,
which
summarizes
abstracts
lectures
delivered
at
two-day
European
Federation
Laboratory
Medicine
(EFLM)
Preanalytical
Conference
entitled
“New
Insight
Quality”
(Padova,
Italy;
December
12–13,
2025),
provides
comprehensive
overview
errors,
offers
some
important
insights
into
less
obvious
sources
vulnerability
proposes
efficient
Language: Английский
Integrated device for plasma separation and nucleic acid extraction from whole blood toward point-of-care detection of bloodborne pathogens
Abigail G. Ayers,
No information about this author
Christia M. Victoriano,
No information about this author
Samuel K. Sia
No information about this author
et al.
Lab on a Chip,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 1, 2024
This
work
presents
PRECISE,
a
device
that
integrates
plasma
separation
and
nucleic
acid
extraction,
enabling
streamlined
sample
preparation
of
whole
blood
for
point-of-care
diagnostics
without
external
equipment
or
electricity.
Language: Английский
Analytical and bioanalytical chemistry for digital diagnostics in digital healthcare
Analytical and Bioanalytical Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 31, 2024
Language: Английский
Blood self-sampling: friend or foe?
Clinical Chemistry and Laboratory Medicine (CCLM),
Journal Year:
2024,
Volume and Issue:
63(1), P. 1 - 2
Published: Oct. 9, 2024
Comparison of capillary finger stick and venous blood sampling for 34 routine chemistry analytes: potential for in the hospital and remote blood sampling
Clinical Chemistry and Laboratory Medicine (CCLM),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 18, 2024
Abstract
Objectives
This
study
examined
the
comparability
of
venous
and
capillary
blood
samples
with
regard
to
routine
chemistry
analytes.
Methods
Venous
were
collected
from
adult
patients
assess
alanine
transaminase,
albumin,
alkaline
phosphatase,
apolipoprotein
B,
aspartate
aminotransferase,
total
bilirubin,
calcium,
chloride,
creatin
kinase,
creatinine,
C-reactive
protein,
ferritin,
folic
acid,
free
T4,
gamma
glutamyltransferase,
glucose,
high
density
lipoprotein
cholesterol,
iron,
lipase,
a,
magnesium,
phosphate,
postassium,
prostate
specific
antigen,
sodium,
transferrin,
triglycerides,
thyroid
stimulating
hormone,
urate,
urea,
vitamin
B12
25-hydroxyvitamin-D3.
Furthermore,
hemolysis-icterus-lipemia
Index
(HIL-Index)
was
measured
for
all
samples.
All
measurements
performed
using
Siemens
Atellica
®
CH
or
IH
Analyzer.
Deming
regression
analysis
mean
relative
differences
between
each
analyte
contrasted
desirable
allowable
error
(TEa)
Clinical
Laboratory
Improvement
Amendments
(CLIA)
2024
proposed
acceptance
limits
proficiency
testing.
Results
demonstrated
excellent
most
Conclusions
Capillary
showed
comparable
results
almost
studied
Of
33
analytes
which
TEa
criteria
where
available,
30
met
criteria.
CLIA
available
29
only
glucose
did
not
meet
In
conclusion,
draw
is
a
suitable
alternative
sampling
measuring
investigated
benefits
fear
needles
might
pave
way
remote
self-sampling.
Language: Английский