Biosynthesis of Chitosan Nanocomposite with Myrrh-Mediated Nanosilver for Controlling Skin Pathogenic Microbes DOI Creative Commons

Hager A. Saad,

Mona Assas,

Asmaa Abdella

et al.

Natural Product Communications, Journal Year: 2024, Volume and Issue: 19(11)

Published: Nov. 1, 2024

Background: The usages of biosynthesized nanomaterials for microbial pathogens’ fighting have numerous rationales and effectiveness. Skin microbes could acquire drug-resistance that needs innovative approaches overcoming. Objectives: Phytosynthesized silver nanoparticles (AgNPs) with Commiphora myrrh resin extract (MR) their nanoconjugates chitosan (Cht) were fabricated assessed as potential antimicrobial agents controlling antibiotic-resistant skin pathogens, Materials methods: AgNPs biosynthesis was achieved within MR solution they composited Cht. syntheses validated using infrared spectroscopy electron microscopy loaded onto cotton textiles, then all nanomaterials/textiles inhibiting pathogens Staphylococcus aureus Candida albicans. Results: Nanomaterials’ characterization appointed the mean size MR-synthesized to be 22.58 nm, whereas diameter Cht/MR/AgNPs nanocomposites 130.34 nm carry +25.9 mV charges. assessment interactions between employed materials. textiles MR/AgNPs effectively inhibit growth albicans, most powerful. scanning confirmed action toward pathogens; mostly lysed deformed 12 h exposure nanocomposites. Conclusions: nanocomposite provided potent actions pathogens.

Language: Английский

Potent antibacterial nanocomposites from okra mucilage/chitosan/silver nanoparticles for multidrug-resistant Salmonella Typhimurium eradication DOI Creative Commons
Haddad A. El Rabey,

Rehab F. Almassabi,

Ghena M. Mohammed

et al.

Green Processing and Synthesis, Journal Year: 2024, Volume and Issue: 13(1)

Published: Jan. 1, 2024

Abstract The polymeric nanocomposites (NCs), constructed from okra ( Abelmoschus esculentus ) fruits mucilage (OM), silver nanoparticles (AgNPs), and chitosan (Ch), were fabricated as potential candidates to overcome drug-resistant Salmonella Typhimurium bacteria. AgNPs directly mediated by OM, with 4.2 nm mean diameters. composed NCs Ch/OM/AgNPs innovatively synthesized the various ratios of Ch:OM/AgNPs affected particles’ size charges. infrared analysis employed materials/NCs validated their interactions conjugations. antibacterial assays against different resistant S. strains indicated efficiency inhibit bacteria significant superiority over standard antibiotics. that contained equal Ch OM/AgNPs best formulation (mean diameter, 47.19 surface charge, +16.9 mV) exhibit strongest actions toward Typhimurium. caused severe deformation, destruction, lysis in exposed bacteria, traced scanning microscopy. biosynthesis using OM nanoconjugation provided effectual natural biopolymers enhanced expected biosafety S . strains, which supports applications disinfectant, sterilizing, curative agents.

Language: Английский

Citations

4
Antimicrobial and Cytotoxic Effect of Positively Charged Nanosilver-Coated Silk Sutures DOI Creative Commons

Diego Antonio Monroy Caltzonci,

Aruna‐Devi Rasu Chettiar,

Verónica Campos Ibarra

et al.

ACS Omega, Journal Year: 2024, Volume and Issue: unknown

Published: April 7, 2024

Sutures are a crucial component of surgical procedures, serving to close and stabilize wound margins promote healing. However, microbial contamination sutures can increase the risk site infections (SSI) due colonization by pathogens. This study aimed tackle SSI synthesizing positively charged silver nanoparticles (P-AgNPs) using them produce antimicrobial sutures. The P-AgNPs were reduced stabilized polyethylenimine (PEI), cationic branched polymer. physiochemical characteristics confirmed from surface plasmon resonance (SPR) peak at 419 nm, spherical morphology with particle size range 8–10 PEI functional groups on NPs, hydrodynamic diameter 12.3 ± 2.4 zeta potential 31.3 6 mV. Subsequently, surfaces silk impregnated different time intervals (24, 48, 96 h) an ex situ method. Scanning electron microscopy (SEM) tensile strength studies conducted determine coating durability NP-coated NPs quantified inductively coupled plasma optical emission spectrophotometry (ICP-OES), which was in 1–5 μg. Primarily, activity studied three microorganisms (Candida albicans, Streptococcus mutans, Staphylococcus aureus) for both suture-coated agar diffusion results showed that only exhibited enhanced effects against bacteria fungi. Finally, cytotoxicity investigated stem cells apical papilla (SCAPs) 24 h, more than 75% cell viability. Overall, indicate potentially be used as diminish or inhibit postoperative general surgery patients.

Language: Английский

Citations

4
Application of Cystoseira myrica phycosynthesized selenium nanoparticles incorporated with nano‐chitosan to control aflatoxigenic fungi in fish feed DOI
Ahmed A. Tayel,

Karima M El‐madawy,

Shaaban H. Moussa

et al.

Journal of the Science of Food and Agriculture, Journal Year: 2024, Volume and Issue: 104(12), P. 7678 - 7687

Published: May 22, 2024

The recurrent contaminations of feed materials with mycotoxigenic fungi can endanger both farmed animals and humans. Biosynthesized nanomaterials are assumingly the ideal agents to overcome fungal invasion in feed/foodstuffs, especially when utilizing sustainable sources for synthesis. Herein, phycosynthesis selenium nanoparticles (SeNPs) was targeted using Cystoseira myrica algal extract (CE), conjugation CE/SeNPs chitosan (NCt) produce potential antifungal nanocomposites controlling Aspergillus flavus isolates fish feed.

Language: Английский

Citations

4
Preparation of nanosilver/polymer composites and evaluation of their antimicrobial and antitumor effect DOI Creative Commons

Feifei Lu,

Yuxin Liu,

Yingxin Dai

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(8), P. 6357 - 6369

Published: Jan. 1, 2025

A copolymer (PVA- g -PEG) of polyethylene glycol (PEG) and polyvinyl alcohol (PVA) was synthesized by grafting PEG chains onto PVA backbone to prepare the silver nanoparticles/polymer composite (AgNPs).

Language: Английский

Citations

0
Influential eradication of resistant Salmonella Typhimurium using bioactive nanocomposites from chitosan and radish seed-synthesized nanoselenium DOI Creative Commons
Haddad A. El Rabey,

Rehab F. Almassabi,

Ghena M. Mohammed

et al.

Green Processing and Synthesis, Journal Year: 2024, Volume and Issue: 13(1)

Published: Jan. 1, 2024

Abstract Biosynthesized nanomaterials and nanocomposites (NCs) could have promising potentialities to overcome the multi-drug-resistant (MDR) pathogenic bacteria, particularly Salmonella Typhimurium . Radish seed ( Raphanus sativus ) mucilage (RSM) was employed for synthesizing/capping selenium nanoparticles (SeNPs) their nanoconjugates with chitosan (Ct) were assessed inhibiting MDR S. typhimurium The SeNPs effectually biosynthesized using RSM 4.21 nm mean size −25.6 mV surface charge. Different NC formulations of Ct/RSM/SeNPs generated validated infrared spectroscopy electron microscopy. entire suppress growth, including strains. F3 NCs (with 53.64 diameter +21.1 charge) had strongest anti- activity that exceeded action cephalosporin, subsequent antibacterial formulation F2 41.77 −17.3 charge). severely destruct, deform, lyse cells’ structures throughout 10 h exposure. innovative fabricated are auspiciously suggested as effectual biocides eradicate in various food-processing facilities.

Language: Английский

Citations

0
Anti-Helicobacter pylori activity of nanocomposites from chitosan/broccoli mucilage/selenium nanoparticles DOI Creative Commons

Ahlam A. S. Aborabu,

Ahmed A. Tayel,

Mona Assas

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Sept. 17, 2024

Helicobacter pylori can infect most people worldwide to cause hazardous consequences health; the bacteria could not easily be controlled or disinfected. Toward exploring of innovative biocidal nanoformulations control H. pylori, broccoli seeds (Brassica oleracea var. italica) mucilage (MBS) was employed for biosynthesizing selenium nanoparticles (MBS/SeNPs), which intermingled with chitosan (NCT) generate bioactive nanocomposites suppressing pylori. The MBS effectually and stabilize SeNPs 13.61 nm mean diameter, where NCT had 338.52 diameter positively charged (+ 39.62 mV). cross-linkages between NCT-MBS-SeNPs were verified via infrared analysis from NCT:MBS/SeNPs at 1:2 (T1), 1:1 (T2) 2:1 (T3) ratios diameters 204, 132 159 nm, respectively. entire nanomaterials/composites exhibited potent anti- activities using various assaying methods; T2 nanocomposite utmost bactericidal agent 0.08-0.10 mg/L minimal concentration 25.9-27.3 mm inhibition zones. scanning microscopy displayed ability attach bacterial cells, disrupt their membranes, completely lyse them within 10 h. NCT/MBS/SeNPs provided effectual approach

Language: Английский

Citations

0
Green synthesis of La2O3–LaPO4 nanocomposites using Charybdis natator for DNA binding, cytotoxic, catalytic, and luminescence applications DOI Creative Commons

Rajendran Muthukumar Sivaraman,

Kirubaharan Daphne Jacinth Gracia,

Seth Sheeba Thavamani

et al.

Green Processing and Synthesis, Journal Year: 2024, Volume and Issue: 13(1)

Published: Jan. 1, 2024

Abstract A one-step biosynthetic pathway for the fabrication of La 2 O 3 –LaPO 4 nanocomposites (NCs) was developed, employing Charybdis natator . The structure and phase changes NCs were confirmed, their diverse applications explored. peaks at 206, 332, 442 nm in UV-DRS studies confirmed formation NCs. Fourier transform infrared spectral analysis revealed La–O stretching 716 cm −1 presence PO 4 3 − {\text{PO}}_{4}^{3-} bands 532, 560, 578, 618 X-ray diffraction patterns showed a hexagonal with θ 11.04 28.57 monoclinic LaPO phases = 18.79 41.88. photoelectron spectroscopy data binding energy 836.04 852.77 eV, corresponding to 3d 5/2 3/2 lanthanum. average particle size from HR-TEM 28.95 after annealing 800°C SAED crystalline nature. high affinity towards ctDNA established by constant value 2.08 (mg·mL ) Under UV exposure, 96% degradation efficiency methyl orange within 120 min pH displayed, rate 2.72 × 10 −2 affirming photocatalytic potential. Their biocompatibility assessed through MTT assay luminescence characteristics evaluated.

Language: Английский

Citations

0
Biosynthesis of Chitosan Nanocomposite with Myrrh-Mediated Nanosilver for Controlling Skin Pathogenic Microbes DOI Creative Commons

Hager A. Saad,

Mona Assas,

Asmaa Abdella

et al.

Natural Product Communications, Journal Year: 2024, Volume and Issue: 19(11)

Published: Nov. 1, 2024

Background: The usages of biosynthesized nanomaterials for microbial pathogens’ fighting have numerous rationales and effectiveness. Skin microbes could acquire drug-resistance that needs innovative approaches overcoming. Objectives: Phytosynthesized silver nanoparticles (AgNPs) with Commiphora myrrh resin extract (MR) their nanoconjugates chitosan (Cht) were fabricated assessed as potential antimicrobial agents controlling antibiotic-resistant skin pathogens, Materials methods: AgNPs biosynthesis was achieved within MR solution they composited Cht. syntheses validated using infrared spectroscopy electron microscopy loaded onto cotton textiles, then all nanomaterials/textiles inhibiting pathogens Staphylococcus aureus Candida albicans. Results: Nanomaterials’ characterization appointed the mean size MR-synthesized to be 22.58 nm, whereas diameter Cht/MR/AgNPs nanocomposites 130.34 nm carry +25.9 mV charges. assessment interactions between employed materials. textiles MR/AgNPs effectively inhibit growth albicans, most powerful. scanning confirmed action toward pathogens; mostly lysed deformed 12 h exposure nanocomposites. Conclusions: nanocomposite provided potent actions pathogens.

Language: Английский

Citations

0