Prospects of green nanotechnology for efficient management of neurodegenerative diseases

Frontiers in Nanotechnology, Journal Year: 2022, Volume and Issue: 4

Published: Nov. 1, 2022

Current theranostics for neurodegenerative diseases (NDD) management are majorly symptomatic due to a lack of identification early-stage biomarkers and the inefficiency drugs penetrate through blood-brain barrier. Recently, Neuro-nanotechnology interface has emerged as potential strategy diagnosis, monitoring, treatment NDDs owing smaller particle size, high specific surface area, tunable physicochemical attributes rich functionalities. However, toxicity biocompatibility two significant challenges restricting their commercial prospect in NDD management. On contrary, green nanosystems fabricated using plant extracts, microorganisms, biome-based precursors, repurposed-byproducts, exosomes, protein-based bio-nanomaterials economical, eco-friendly, biocompatible renewable abundance biodiversity. This explores novel cutting-edge developing diagnostic implantable devices, targeted drug delivery strategies, surgical prostheses, therapeutics, treatment, nanoscaffolds neurogeneration, immunity development. Besides, it discusses challenges, alternate solutions advanced prospects with integration modern-age technologies development sustainable efficient NDDs.

Language: Английский

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Plant extract-mediated synthesis Cobalt doping in zinc oxide nanoparticles and their in vitro cytotoxicity and antibacterial performance

Heliyon, Journal Year: 2023, Volume and Issue: 9(9), P. e19659 - e19659

Published: Aug. 31, 2023

In this research, zinc oxide (ZnO) nanoparticles doped with different percentages of produced cobalt using the green synthesis method. ZnO showed good cellular and microbial toxicity due to their high surface-to-volume ratio. Adding metal nanostructure can lead appearance a new feature. To investigate effect adding metal, synthesized containing 3 6% were plant extract. The resulting nanostructures characterized by Raman spectroscopy, UV–Visible spectrometer, X-ray diffraction, Field emission scanning electron microscopy. Ultimately, samples' cytotoxicity antimicrobial tests performed. XRD confirmed formation hexagonal wurtzite structure. imaging that doping resulted in decrease average crystal size. results doping, particle size decreased slightly. effects all three studies, leads an increase compared non-doped nanoparticles.

Language: Английский

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Recent advances in the use of inorganic nanomaterials as anti caries agents

Heliyon, Journal Year: 2023, Volume and Issue: 9(4), P. e15326 - e15326

Published: April 1, 2023

Caries is the most prevalent and widespread chronic oral disease. Traditional caries filling materials, due to their lack of anti-caries capabilities, can readily develop secondary caries. Nanomaterials proposed as an effective approach for treatment inhibit biofilm formation. It also not only reduce demineralization but promote remineralization. In recent years, nanotechnology in particularly nano-adhesive nano-composite resin, has advanced rapidly. Because inorganic nanoparticles (NPs) interfere with bacterial metabolism development, NPs have emerged a new trend dental applications. Metal metal oxide by releasing ions, oxidative stress induction, non-oxidative mechanisms showed significant antimicrobial activity. For applying anti agents, silver, zinc, titanium, copper, calcium ions been shown attention. Moreover, fluoride functionalized were employed improve efficacy them. The fluoride-functionalized remineralization, enhancing apatite this review, we provided overview advances use agents. Furthermore, antimicrobial, remineralizing, mechanical impacts on materials discussed.

Language: Английский

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Biosynthesis of silver nanoparticles using Lawsonia inermis and their biomedical application

IET Nanobiotechnology, Journal Year: 2022, Volume and Issue: 16(7-8), P. 284 - 294

Published: Aug. 30, 2022

Developing biosynthesis of silver nanoparticles (Ag-NPs) using plant extract is an environmentally friendly method to reduce the use harmful chemical substances. The green synthesis Ag-NPs by Lawsonia inermis and its cellular toxicity antimicrobial effect was studied. physical properties synthesised were investigated UV-visible spectroscopy, infrared X-ray diffraction (XRD), scanning, transmission electron microscopy. average size 40 nm. XRD result shows peaks at 2θ = 38.07°, 44.26°, 64.43°, 77.35° are related FCC structure Ag-NPs. Cytotoxicity evaluated MTT test on breast cancer MCF7 cell line. Observations showed that cytotoxicity studied line depended concentration time. obtained IC50 considered for cells a dose 250 μg/ml. Growth survival rates decreased exponentially with dose. Antimicrobial against Escherichia coli, Salmonella typhimurium, Bacillus cereus, Staphylococcus aureus calculate minimum inhibitory bactericidal (MBC). results have properties. lowest can inhibit growth bacterial strains 25

Language: Английский

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An intelligent DNA nanorobot for detection of MiRNAs cancer biomarkers using molecular programming to fabricate a logic-responsive hybrid nanostructure

Bioprocess and Biosystems Engineering, Journal Year: 2022, Volume and Issue: 45(11), P. 1781 - 1797

Published: Sept. 20, 2022

Language: Английский

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Green Ferrites: Eco‐Friendly Synthesis to Applications in Environmental Remediation, Antimicrobial Activity, and Catalysis—A Comprehensive Review

Applied Organometallic Chemistry, Journal Year: 2025, Volume and Issue: 39(2)

Published: Jan. 14, 2025

ABSTRACT Ferrite magnetic materials have emerged as capable in engineering, research, and medicine because of their exclusive fascinating properties obtained from a variety synthesis techniques. These ferrites are significant commercial products, biomedical applications. Green methods for ferrite nanocomposites nanoparticles becoming increasingly popular due to usefulness range industries, environmental, medicinal remediation. (MFe 2 O 4 , where M = Ni, Cu, Mg, Co, Zn, Mn) recently gained popularity many uses biological, chemical interactions. This review covers the most recent investigations over last few years on green‐synthesized nanoparticles, containing nanocomposites, more elements, with focus microorganism‐mediated plant‐based processes. The surface features synthesized green discussed, is potential sensors, energy, water treatment, antibacterial activity, heavy metal removal article presents an inclusive overview ferrites, including research advances findings. To fully realize promise nanoferrites several fields, thorough understanding manufacturing, properties, applications essential. Green‐synthesized chosen improved control particle size shape, lower cost, decreased toxicity, environmental friendliness, all which preserve that better than those conventionally making them sustainable choice

Language: Английский

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Bioinspired green synthesis of nanoparticles by plants to fight against multidrug resistant microbes

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 439 - 480

Published: Jan. 1, 2025

Language: Английский

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Magnetic and antibacterial properties of substituted cobalt spinel ferrite nanocomposites synthesized via henna green microwave hydrothermal method

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: May 13, 2025

A novel henna-green/microwave-assisted hydrothermal method was applied to synthesize cobalt-manganese spinel ferrite nanocomposites. This eco-friendly approach, utilizing henna extract as a capping agent, combined with microwave-assisted technique, offers advantages such environmental sustainability, time, and energy efficiency. Examined parameters included pH (10 ± 1), temperatures (175 25 °C), durations (15, 30 15 min), forty milliliters of prepared varying quantities (five, ten, or fifteen grams per hundred water). Post-optimization, various substituents like nickel chromium were explored. Samples calcined at 500 °C, 700 900 analyzed using Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM), Transmission (TEM), photoelectron spectroscopy (XPS), magnetic property assessments. XRD revealed cubic face-centered hematite structure. SEM TEM showed diverse morphologies (rod-like, flower-like, polygonal) influenced by synthesis conditions substituents. XPS confirmed Co2+, Mn2+, Ni2+, Fe3+, Cr3+ presence in the lattice. The nanocomposites exhibited ferromagnetic behavior saturation magnetization (Ms) values from 23.53 55.15 emu/g. Chromium substitution best antimicrobial activity against Escherichia coli, Staphylococcus aureus, Candida albicans. study highlights potential for controlled substituted cobalt tunable properties applications.

Language: Английский

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Retracted: Synthesis characterization of Zn-based MOF and their application in degradation of water contaminants

Water Science & Technology, Journal Year: 2022, Volume and Issue: 86(9), P. 2303 - 2335

Published: Oct. 11, 2022

Abstract Water Science & Technology issues a formal retraction in relation to the above article by Saade Abdalkareem Jasim et al. The publisher this for following reasons. Following publication, concerns were raised regarding potential citation manipulation article, due large number of inappropriate references. journal did not receive satisfactory response these and during investigation additional about authorship including authors' contributions. Editors-in-Chief therefore no longer have confidence reliability findings presented.

Language: Английский

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Green synthesis routes for spinel ferrite nanoparticles: a short review on the recent trends

Journal of the Australian Ceramic Society, Journal Year: 2023, Volume and Issue: 59(5), P. 1161 - 1175

Published: July 1, 2023

Language: Английский

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