European Journal of Oncology Nursing, Journal Year: 2024, Volume and Issue: 71, P. 102657 - 102657
Published: July 1, 2024
Language: Английский
Cancer Reports, Journal Year: 2024, Volume and Issue: 7(2)
Published: Feb. 1, 2024
Abstract Background Studies have indicated that apart from enhancing patient survival, chemotherapy has adverse side effects on the psychological, social, and cognitive functions of breast cancer survivors. Aims This study was conducted to understand chemotherapy's impact survivors' functions. Methods Results Our is a systematic review based Preferred Reporting Items for Systematic Reviews Meta‐Analyses (PRISMA) statement. We searched English databases, including PubMed/MEDLINE, PsycINFO, Web Science, Persian such as Irandoc Elmnet, using keywords cancer, chemotherapy, functions, executive neuropsychological Two reviewers independently evaluated full text articles according predefined criteria. Among 937 available studies, 26 were selected inclusion exclusion criteria, which 17 (65%) longitudinal 9 (35%) cross‐sectional. The findings significant relationship between use impairments, most notably attention, working short‐term memory, However, studies differed in their regarding long‐term persistence cancer‐related impairment (CRCI), could be due wide range tools used, different methods measure difference sample size studies. Conclusion Chemotherapy, affecting cortical subcortical brain structures, causes set impairments can lead social responsibility acceptance, daily functioning, quality life women. Therefore, rigorous extensive research design required consequences CRCI standardized sensitive measures Specifically, comparing regimens cognition potential mechanisms and/or moderators would instrumental designing more effective therapy evaluating efficacy cost‐effectiveness rehabilitation supportive care programs.
Language: Английский
Citations
12
Supportive Care in Cancer, Journal Year: 2024, Volume and Issue: 32(4)
Published: March 5, 2024
Abstract Purpose Cancer-related cognitive impairment (CRCI) is a significant risk factor influencing the quality of life in lung cancer survivors. No absolute assessment tool has been confirmed to assess CRCI This review was undertaken pool overall prevalence and summarize tools assessing among Methods PubMed, Cochrane Library, Embase, CINAHL, CNKI were searched retrieve articles reported prevalence. Summary estimates pooled using random effects model, along with corresponding 95% prediction intervals (PIs). The Freeman-Tukey double arcsine transformation proportions incorporated analysis. Additionally, subgroup analysis, meta-regression, leave-one-out analysis performed. Results A total 12 studies, involving 1934 survivors, included review. All these studies found have low bias terms their methodological quality. Four (33.3%) utilized International Cognition Cancer Task Force (ICCTF) criteria identify through neuropsychological tests. rate be 26% (95% PI, 16–37%), I 2 = 95.97%. region which conducted identified as contributing this heterogeneity ( p 0.013). indication small-study (Egger’s test: 0.9191). Conclusion provides an overview findings can serve epidemiological evidence enhance clinicians’ researchers’ understanding early detection assessment.
Language: Английский
Citations
10
BMJ Open, Journal Year: 2023, Volume and Issue: 13(1), P. e058088 - e058088
Published: Jan. 1, 2023
Objectives Cognitive training is a non-drug intervention to improve the cognitive function of participants by them in different domains. We investigated effectiveness for patients with breast cancer reporting changes. Design Systematic review and meta-analysis. Data sources PubMed, Embase, Cochrane Library, WOS, CINAHL, CNKI, VIP, SinoMed, Wanfang, Grey literature trial registries were searched (from inception 1 October 1, 2022). Eligibility criteria Inclusion randomized controlled trials (RCTs) assessing effects on changes The primary outcome was subjective function. Secondary outcomes objective functioning (eg, executive attention) psychological outcomes(eg, anxiety, depression, fatigue). extraction synthesis Two reviewers worked independently screen literature, extract data, assess methodological quality risk bias included studies. Results are reported as standardizedstandardised mean differences (SMDs) 95% confidence intervals(CI). Grades Recommendation, Assessment, Development, Evaluation(GRADE) used evidence. Main measures depression A total 9 RCTs involving 666 included. frequency varied duration mostly focused 5–12 weeks. It can be delivered an individual or group mode, both online face face. Meta-analysis revealed that aimed at adaptive field has statistically significant improving (SMD=0.30, CI (0.08 0.51), moderate certainty). Some functions such processing speed (SMD=0.28, (0.02 0.54), low certainty), verbal memory (SMD=0.32, (0.05 0.58), working (SMD=0.39, (0.17 0.61), certainty) episodic (SMD=0.40, (0.11 0.69), significantly improved after intervention. In addition, we did not find attention, short-term memory, execution function, anxiety fatigue Subgroup analyses based delivery sessions, use web-based software may more beneficial Conclusion Evidence certainty suggests cognition, speed, But it patients’ fatigue. PROSPERO registration number CRD42021264316.
Language: Английский
Citations
15
JNCI Journal of the National Cancer Institute, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 11, 2024
Cancer and its care create substantial financial, time, administrative burdens both for patients their loved ones. While cancer-related financial have been well documented in the past decade, time of cancer received substantially less attention. We define as burden caregivers experience due to needed complete treatment tasks that take away from other life responsibilities. Relatedly, we conceptualize those cancer-related, resource-consuming bureaucratic logistical tasks. Finally, hardship can be conceptualized problems related cost medical care. These do not exist isolation; administrative, intersect with compound each other. Currently, limited evidence-based measures on objective (e.g., scheduling transportation, wait time) subjective mental, emotional physical stress) burden. even more evidence risk factors outcomes increased burdens, how they differentially impact populations across social demographic groups. In this commentary, present a research agenda map, measure, evaluate, mitigate
Language: Английский
Citations
4
World Journal of Cancer Research, Journal Year: 2025, Volume and Issue: 15(01), P. 9 - 15
Published: Jan. 1, 2025
Language: Английский
Citations
0
PLoS ONE, Journal Year: 2025, Volume and Issue: 20(2), P. e0318984 - e0318984
Published: Feb. 6, 2025
Background Chemotherapy-related cognitive impairment (CRCI) is a common adverse effect of chemotherapy in breast cancer patients, with high incidence that significantly impacts treatment adherence and quality life. Currently, there no definitive effective for CRCI. Research indicates acupuncture may serve as promising intervention This study aims to assess the effectiveness treating Methods guided by Preferred Reporting Items Systematic Reviews Meta-Analysis Protocols (PRISMA-P). From time database construction October 2024, we will search seven literature databases, three clinical registry sources gray literature. The restricted languages are English Chinese. We use Participants-Interventions-Comparators-Outcome-Conclusion-Study Design (PICOS) criteria identify included studies RoB2 tool studies. Data synthesis meta-analysis be performed using RevMan 5.3. Discussion results this clarify potential benefits CRCI address existing disagreements about its efficacy. Furthermore, findings assist clinicians making informed decisions regarding Trail registration PROSPERO number: CRD42024568093 .
Language: Английский
Citations
0
Seminars in Oncology Nursing, Journal Year: 2025, Volume and Issue: unknown, P. 151809 - 151809
Published: Feb. 1, 2025
Anxiety and depression are common symptoms in oncology patients undergoing chemotherapy. Study purpose was to evaluate for differences severity of (ie, fatigue, energy, sleep disturbance, cognitive function, pain) quality life (QOL) outcomes among three subgroups outpatients with distinct joint anxiety profiles. Oncology (N = 1328) completed measures state depression, six times over two cycles Latent profile analysis done identify AND Patients trait anxiety, morning evening pain, as well generic disease-specific QOL at enrollment. Differences the classes symptom scores were evaluated using parametric non-parametric tests. Three profiles identified named: Low Depression (57.5%, Both Low), Moderate (33.7%, Moderate), High (8.8%, High). All showed a "dose-response effect" worsened, all increased). Likewise, both general (except spiritual well-being) measures, decreased worsened. Compared classes, other reported lower well-being domain. More than 40% receiving chemotherapy experience moderate high levels depression. These report an extremely burden significant decrements domains QOL. Clinicians need perform comprehensive assessments during In addition, referrals targeted interventions needed manage multiple improve patients'
Language: Английский
Citations
0
Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 16
Published: April 30, 2025
Gliomas, particularly glioblastoma (GBM), are among the most aggressive and challenging brain tumors to treat. Although current therapies such as chemotherapy, radiotherapy, targeted treatments have extended patient survival some extent, their efficacy remains limited is often accompanied by severe side effects. In recent years, exercise therapy has gained increasing attention an adjunctive treatment in clinical research settings. Exercise not only improves patients’ physical function cognitive abilities but may also enhance of conventional drug modulating immune system, suppressing inflammatory responses, improving blood-brain barrier permeability. This review summarizes potential mechanisms glioma treatment, including enhancing surveillance through activation natural killer (NK) cells T cells, penetration function. Additionally, studies suggest that can synergize with chemotherapy immunotherapy, outcomes while reducing drug-related application patients still exploratory phase, existing evidence indicates its significant value approach, become a new standard future.
Language: Английский
Citations
0
Frontiers in Psychology, Journal Year: 2025, Volume and Issue: 16
Published: April 30, 2025
Early diagnosis and effective treatments have favored the survival of cancer patients but also generated adverse consequences including cognitive impairment psychological distress, which are related to both disease progression side effects pharmacological agents. However, there is little data in literature concerning such with lung cancer. Here, we describe protocol a study aiming investigate occurrence non-small-cell small-cell undergoing adjuvant therapies or surgery year following enrollment. This longitudinal will recruit around 200 patients. To explore profile pre- post-oncological treatment, evaluation be administered each patient at baseline (T0), 4 (T1), 12 months (T2) after end treatments. A screening assessed Montreal Cognitive Assessment Mini-Mental State Examination. Executive functions investigated Frontal Battery, Stroop Color Word test phonemic fluency test. Memory learning examined Rey's auditory verbal test, whereas working memory Digit Span Corsi Block-tapping Test. Finally, attention Trail Making Test Symbol Modalities In addition, perceived impairment, anxious depressive symptoms, reserve, sleep patterns, patient's quality life using self-report tools. The identified by adopting criteria proposed International Cognition Cancer Task Force. trial received approval from ethical committee Institutes Scientific Research Healthcare, IRCCS, European Institute Oncology (UID_IEO 2027). results could relevant implications for managing its impact on Through systematic assessment associated risk factors, this aims provide valuable insights into clinical practice, enhancing development neuropsychological protocols.
Language: Английский
Citations
0
Supportive Care in Cancer, Journal Year: 2022, Volume and Issue: 30(11), P. 9607 - 9614
Published: Sept. 30, 2022
Language: Английский
Citations
13