International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(19), P. 10539 - 10539
Published: Sept. 30, 2024
Cancer
therapy
is
constantly
evolving,
with
a
growing
emphasis
on
targeted
and
efficient
treatment
options.
In
this
context,
graphene
quantum
dots
(GQDs)
have
emerged
as
promising
agents
for
precise
drug
gene
delivery
due
to
their
unique
attributes,
such
high
surface
area,
photoluminescence,
up-conversion
biocompatibility.
GQDs
can
damage
cancer
cells
exhibit
intrinsic
photothermal
conversion
singlet
oxygen
generation
efficiency
under
specific
light
irradiation,
enhancing
effectiveness.
They
serve
direct
therapeutic
versatile
platforms
capable
of
being
easily
functionalized
various
targeting
molecules
agents.
However,
challenges
achieving
uniform
size
morphology,
bandgap
engineering,
scalability,
along
minimizing
cytotoxicity
the
environmental
impact
production,
must
be
addressed.
Additionally,
there
need
more
comprehensive
understanding
cellular
mechanisms
release
processes,
well
improved
purification
methods.
Integrating
into
existing
systems
enhances
efficacy
traditional
treatments,
offering
less
invasive
options
patients.
This
review
highlights
transformative
potential
in
while
acknowledging
that
researchers
overcome
broader
application.
Nanotechnology Reviews,
Journal Year:
2023,
Volume and Issue:
12(1)
Published: Jan. 1, 2023
Abstract
Solid
lipid
nanoparticles
(SLNs),
the
spheroidal-shaped,
colloids
state
lipophilic-natured,
innovative
nanoscale
particulate
materials,
are
being
concurrently
prepared
by
quality-by-design
approach
for
cellular
and
sub-cellular
delivery
of
drugs
other
payloads
with
facilitated
physicochemical
characteristics
targeted
delivery.
The
drugs,
pharmaceuticals
biopharmaceutical
genes
to
diseased
body
organs,
tissues,
mass
have
been
developed
as
promising
nanocarriers
different
high-incidence
cancers
disease
therapies,
including
Alzheimer’s,
Parkinson’s,
tuberculosis.
SLNs
evolved
favorable
lipid-based
formulation,
served
oral
intravenous
carriers
that
drug
stable
sterile
transport,
sustained
delivery,
controlled
drug/payload
deloading,
requisite
biodistributions.
advantages,
shortcomings,
bottlenecks
discussed
plausible
remediation
strategies.
laboratory-scale
bulk
preparations,
use
lipids
in
various
preparation,
surface
coatings,
properties
final
product,
characterization
protocols
also
encompassed,
routes
administrations,
specific-sites-targeting,
on-site
outreach
biocompatibility,
bioavailability,
absorption,
distribution,
metabolism,
excretion
pharmacokinetics,
pharmacodynamics
inputs
relevance
therapy.
Plausible
applications
complex
genetic
disorders,
personalized
medicine,
traditional
alternative
medicine
prospects,
discussed.
ACS Nano,
Journal Year:
2024,
Volume and Issue:
18(3), P. 1757 - 1777
Published: Jan. 8, 2024
Many
systems
have
been
designed
for
the
detection
of
SARS-CoV-2,
which
is
virus
that
causes
COVID-19.
SARS-CoV-2
readily
transmitted,
resulting
in
rapid
spread
disease
human
populations.
Frequent
testing
at
point
care
(POC)
a
key
aspect
controlling
outbreaks
caused
by
and
other
emerging
pathogens,
as
early
identification
infected
individuals
can
then
be
followed
appropriate
measures
isolation
or
treatment,
maximizing
chances
recovery
preventing
infectious
spread.
Diagnostic
tools
used
high-frequency
should
inexpensive,
provide
diagnostic
response
without
sophisticated
equipment,
amenable
to
manufacturing
on
large
scale.
The
application
these
devices
enable
large-scale
data
collection,
help
control
viral
transmission,
prevent
propagation.
Here
we
review
functional
nanomaterial-based
optical
electrochemical
biosensors
accessible
POC
These
incorporate
nanomaterials
coupled
with
paper-based
analytical
inexpensive
substrates,
traditional
lateral
flow
technology
(antigen
antibody
immunoassays),
innovative
biosensing
methods.
We
critically
discuss
advantages
disadvantages
nanobiosensor-based
approaches
compared
widely
technologies
such
PCR,
ELISA,
LAMP.
Moreover,
delineate
main
technological,
(bio)chemical,
translational,
regulatory
challenges
associated
developing
reliable
biosensors,
prevented
their
translation
into
clinic.
Finally,
highlight
how
nanobiosensors,
given
unique
over
existing
tests,
may
future
pandemics.
Advanced Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 3, 2025
Abstract
This
review
underscores
the
transformative
potential
of
photonic
nanomaterials
in
wearable
health
technologies,
driven
by
increasing
demands
for
personalized
monitoring.
Their
unique
optical
and
physical
properties
enable
rapid,
precise,
sensitive
real‐time
monitoring,
outperforming
conventional
electrical‐based
sensors.
Integrated
into
ultra‐thin,
flexible,
stretchable
formats,
these
materials
enhance
compatibility
with
human
body,
enabling
prolonged
wear,
improved
efficiency,
reduced
power
consumption.
A
comprehensive
exploration
is
provided
integration
devices,
addressing
material
selection,
light‐matter
interaction
principles,
device
assembly
strategies.
The
highlights
critical
elements
such
as
form
factors,
sensing
modalities,
data
communication,
representative
examples
skin
patches
contact
lenses.
These
devices
precise
monitoring
management
biomarkers
diseases
or
biological
responses.
Furthermore,
advancements
approaches
have
paved
way
continuum
care
systems
combining
multifunctional
sensors
therapeutic
drug
delivery
mechanisms.
To
overcome
existing
barriers,
this
outlines
strategies
design,
engineering,
system
integration,
machine
learning
to
inspire
innovation
accelerate
adoption
next‐generation
health,
showcasing
their
versatility
digital
applications.
Biosensors and Bioelectronics,
Journal Year:
2025,
Volume and Issue:
273, P. 117180 - 117180
Published: Jan. 25, 2025
Quantum
dots
(QDs)
are
the
smallest
nanomaterials
(2-10
nm),
with
unique
optical
and
electronic
properties.
Thanks
to
these
properties,
QDs
have
been
standing
during
last
years
as
signal
tags
for
different
applications,
including
bioimaging,
fluorescent
biosensors
electrochemical
assays.
In
this
review,
we
explore
current
state-of-the
art
on
nanomaterials,
differentiating
them
between
semiconductor
carbon-based
QDs.
Also,
review
focuses
their
advantages
transducers
in
biosensing
platforms.
Antibiotics,
Journal Year:
2024,
Volume and Issue:
13(2), P. 121 - 121
Published: Jan. 25, 2024
The
development
of
antimicrobial
resistance
(AMR),
along
with
the
relative
reduction
in
production
new
antimicrobials,
significantly
limits
therapeutic
options
infectious
diseases.
Thus,
novel
treatments,
especially
current
era,
where
AMR
is
increasing,
are
urgently
needed.
There
several
ongoing
studies
on
non-classical
therapies
for
diseases,
such
as
bacteriophages,
peptides,
and
nanotechnology,
among
others.
Nanomaterials
involve
materials
nanoscale
that
could
be
used
diagnosis,
treatment,
prevention
This
review
provides
an
overview
applications
nanotechnology
diagnosis
treatment
diseases
from
a
clinician’s
perspective,
focus
pathogens
AMR.
Applications
nanomaterials
by
taking
advantage
their
electrochemical,
optic,
magnetic,
fluorescent
properties,
described.
Moreover,
potential
metallic
or
organic
nanoparticles
(NPs)
infections
also
addressed.
Finally,
use
NPs
safe
efficient
vaccines
reviewed.
Further
needed
to
prove
safety
efficacy
would
facilitate
approval
regulatory
authorities
clinical
use.
