Carbon-based nanomaterials as multifunctional particles for cancer diagnosis and treatment DOI
Naveed Ahmed, Mai Abdel Haleem Abusalah,

Muhammad Absar

et al.

Nano LIFE, Journal Year: 2024, Volume and Issue: 15(04)

Published: Aug. 17, 2024

Carbon-based nanomaterials (NMs) are a specific class of materials used in biomedical applications, such as the delivery therapeutics, imaging, biosensors, tissue engineering, and genetic engineering. NMs interesting tools with qualities, including strong mechanical structure, good conductivity, appealing visual qualities great chemical versatility. Among these carbon-based NMs, graphene carbon nanotubes (CNTs) biological importance. In this paper, we discuss about graphene, CNTs, fullerene quantum dots (CQDs), properties, toxicity, mechanism action applications cancer treatment diagnosis. Graphene, fullerene, CNTs CQDs allotropic forms carbon. The circle engineering is increasing daily, recent years, have played vital role biomaterials. attracted attention wide range researchers due to their multifunctional properties. function detection explore controlling tumor-causing cells damaging cancer-causing cells. If use derivatives source for diagnosis, can cease tumor growth tremendous level.

Language: Английский

Emerging Nanoparticle-Based Diagnostics and Therapeutics for Cancer: Innovations and Challenges DOI Creative Commons

Rachitha Puttasiddaiah,

Nagaraj Basavegowda,

Nityashree Kyathegowdanadoddi Lakshmanagowda

et al.

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(1), P. 70 - 70

Published: Jan. 7, 2025

Malignant growth is expected to surpass other significant causes of death as one the top reasons for dismalness and mortality worldwide. According a World Health Organization (WHO) study, this illness approximately between 9 10 million instances deaths annually. Chemotherapy, radiation, surgery are three main methods treating cancer. These seek completely eradicate all cancer cells while having fewest possible unintended impacts on healthy cell types. Owing lack target selectivity, majority medications have substantial side effects. On hand, nanomaterials transformed identification, diagnosis, management Nanostructures with biomimetic properties been grown late, fully intent observing sickness. nanostructures be consumed by in areas profound disease. Furthermore, because their extraordinary physicochemical properties, which incorporate nanoscale aspects, more prominent surface region, explicit geometrical features, ability embody different substances within or outside surfaces, remarkable nano-vehicles conveying restorative specialists designated regions. This review discusses recent developments nanostructured materials such graphene, dendrimers, cell-penetrating peptide nanoparticles, nanoliposomes, lipid magnetic nano-omics diagnosis

Language: Английский

Citations

2
Nanomaterials in cancer immunotherapy: targeting cancer-associated fibroblasts DOI Creative Commons

Zhongsong Zhang,

Long Chen

Cancer Nanotechnology, Journal Year: 2025, Volume and Issue: 16(1)

Published: Jan. 17, 2025

Emphasizing the significance of cancer-associated fibroblasts (CAFs), non-malignant yet pivotal players within tumor microenvironment (TME), this review illuminates role inflammatory subtype (iCAF) as catalysts in cancer proliferation, metastasis, and therapeutic resistance. Given their paramount importance, targeting CAFs emerges a robust strategy evolving landscape immunotherapy. Nanomaterials, distinguished by unique features malleability, hold considerable promise biomedicine, especially precision-oriented domain therapy. Their aptitude for modulating immune responses, amplifying drug efficacy through precise delivery, discerningly focusing on cells TME situates nanomaterials formidable tools to transcend boundaries set conventional treatments. This scrutinizes convoluted interplay among CAFs, cells, TME. It further showcases widely utilized management. We underscore potential nanoscale delivery systems directed at underscoring transformative power revolutionizing therapies, enhancing precision, culminating improved patient outcomes.

Language: Английский

Citations

2
Biosynthesis of trimetallic nanoparticles and their biological applications: a recent review DOI
Amr H. Hashem, Ebrahim Saied, Bahaa Badr

et al.

Archives of Microbiology, Journal Year: 2025, Volume and Issue: 207(3)

Published: Feb. 1, 2025

Language: Английский

Citations

1
Mapping the intellectual structure and emerging trends on nanomaterials in colorectal cancer: a bibliometric analysis from 2003 to 2024 DOI Creative Commons
Man Lu, Yi Liu,

Jin Zhu

et al.

Frontiers in Oncology, Journal Year: 2025, Volume and Issue: 14

Published: Jan. 8, 2025

Colorectal cancer (CRC) is one of thes most prevalent malignant tumors worldwide. Current therapeutic strategies for CRC have limitations, while nanomaterials show significant potential diagnosing and treating CRC. This study utilizes bibliometric analysis to evaluate the current status trends in this field. Research on from 2003 2024 was retrieved Web Science Core Collection (WOSCC). Tools such as CiteSpace, VOSviewer, RStudio, GraphPad Prism, Excel were used analyze hotspots, covering publication trends, countries, institutions, authors, journals, co-citation analysis, keywords. Visual maps created forecast future developments. The includes 3,683 publications by 17,261 authors 3,721 institutions across 100 countries/regions, published 840 journals. Global steadily increased, particularly since 2018. China leads volume citations, with six top ten research seven cited United States excels citation impact academic centrality. Both countries currently dominate field, underscoring urgent need enhanced international collaboration. Ramezani M Abnous K lead H-index, Siegel RL highly cited. International Journal Nanomedicine has highest volume, Controlled Release In addition "colorectal cancer" "nanoparticles," common keyword "drug delivery." Emerging areas "metal-organic frameworks (MOFs)" "green synthesis" are gaining attention leading hotspots. offers an in-depth application CRC, promoting interdisciplinary collaboration advancing scientific progress

Language: Английский

Citations

0
Nanomaterials in Personalized Medicine: Pioneering Precision Strategies for Cancer Prevention DOI
Muhammad Farooq Umer,

Muhammad Javed Arshed

Published: Jan. 1, 2025

Language: Английский

Citations

0
Exploring nanocomposite materials in clinical dermatology: Innovations for treating skin diseases DOI Creative Commons
Sandipan Dasgupta, Subhasundar Maji, Sanjay Dey

et al.

Next Nanotechnology, Journal Year: 2025, Volume and Issue: 7, P. 100139 - 100139

Published: Jan. 1, 2025

Language: Английский

Citations

0
Applications of Magnetic Nanocomposites and Their Role in Advancing Lateral Flow Assays DOI
Ehsan Sanattalab,

Ezgi Ayni,

Koji Kaya

et al.

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(7)

Published: Feb. 1, 2025

Abstract This article explores the wide‐ranging applications of magnetic nanocomposites and their critical role in advancing lateral flow assays (LFAs) as diagnostic tools. We begin by reviewing a diverse array nanomaterials, including plasmonic, polymer, carbon, silica‐based nanocomposites, well notable examples such CoFe₂O₄, quantum dots, lipid‐based nanoparticles, hydrogels, metal–organic frameworks (MOFs), superparamagnetic iron oxide nanoparticles (SPIONs), gold nanorods. Each type nanocomposite is examined for its unique properties significant potential enhancing sensitivity, stability, multifunctionality. These are used across various sectors, medical diagnostics, environmental monitoring, imaging technology, where they contribute to improved signal strength, binding affinity, biocompatibility. The focuses specifically on application LFAs. rely nanoparticles’ interactions with target molecules achieve detection, providing promising platform point‐of‐care diagnostics. integration enhances detection limits, improves precision, reduces response times, making them an invaluable component rapid tests. By embedding into LFAs, researchers clinicians can more reliable accurate results, facilitating early diagnosis ultimately improving patient outcomes. Their LFAs demonstrates applications, from disease real‐time suggesting transformative impact diagnostics beyond.

Language: Английский

Citations

0
Harnessing Nanoparticle Technology for Precision Medicine in Head and Neck Cancer: Targeted Delivery, Immunomodulation, and Clinical Translation DOI Creative Commons
Karthikeyan Elumalai, Sivaneswari Srinivasan

Nano TransMed, Journal Year: 2025, Volume and Issue: 4, P. 100075 - 100075

Published: Feb. 21, 2025

Language: Английский

Citations

0
Bio‐Inspired Synthesis and Photocatalytic Applications of α‐Fe₂O₃@ZnO Nanobinary Using Laurus nobilis Leaf Extract: Efficient for Anionic and Cationic Dye Degradation With Reusability Studies DOI Open Access
Abderrhmane Bouafia, Salah Eddine Laouini,

Ouarda Ben Ali

et al.

Applied Organometallic Chemistry, Journal Year: 2025, Volume and Issue: 39(4)

Published: March 11, 2025

ABSTRACT This study investigates the sustainable synthesis and applications of α‐Fe₂O₃@ZnO nanocomposites derived using Laurus nobilis leaf extract as a natural reducing agent, promoting eco‐friendly material development for environmental remediation. XRD analysis confirmed formation nanocomposite with crystallite size 21.48 nm, while SEM revealed porous structure uniformly distributed particles ranging from 20 to 50 nm. FTIR spectroscopy identified characteristic Fe‐O Zn‐O bonds, ensuring nanocomposite's purity. Optical showed direct indirect bandgap energies 2.80 1.16 eV, respectively, highlighting its excellent optical properties. The demonstrated remarkable photocatalytic efficiency, achieving 96.3% degradation Brilliant Cresyl Blue (BCB) dye 95.88% Rose Bengal (RB) within 120 min under sunlight irradiation. followed first‐order kinetics, rate constants 0.0241 −1 BCB 0.01875 RB. exhibited reusability, maintaining 93.5% efficiency after five cycles, structural stability throughout repeated use. These results underscore multifunctional potential green‐synthesized dye‐contaminated wastewater treatment, contributing technologies.

Language: Английский

Citations

0
Advances in nanomedicine and delivery systems for gastric cancer research DOI Creative Commons
Sizhe Wang,

Jilei Li,

Zhenyu Zhang

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2025, Volume and Issue: 13

Published: March 21, 2025

The early diagnosis rate of gastric cancer is low, and most patients are already at an advanced stage by the time they diagnosed, posing significant challenges for treatment exhibiting high recurrence rates, which notably diminish patients’ survival quality life. Therefore, there urgent need to identify methods that can enhance efficacy. Nanomedicine, distinguished its small size, targeting specificity, strong biological compatibility, particularly well-suited address toxic side effects associated with current diagnostic therapeutic approaches cancer. Consequently, application nanomedicine delivery systems in has garnered increasing interest from researchers. This review provides overview recent advancements use nanomaterials as drugs or drug research, encompassing their applications diagnosis, chemotherapy, radiotherapy, surgery, phototherapy, explores promising prospects

Language: Английский

Citations

0