Neurochemical Research,
Journal Year:
2023,
Volume and Issue:
49(4), P. 919 - 934
Published: Dec. 20, 2023
The
growing
prevalence
of
aged
sleep-deprived
nations
is
turning
into
a
pandemic
state.
Acute
sleep
deprivation
(SD)
accompanies
aging,
changing
the
hippocampal
cellular
pattern,
neurogenesis
pathway
expression,
and
aggravating
cognitive
deterioration.
present
study
investigated
ability
Near
Infra
Red
(NIR)
light
laser
to
ameliorate
impairment
induced
by
SD
in
young
senile
rats.
Wistar
rats
≤
2
months
(young)
≥
14
(senile)
were
for
72
h
with
or
without
transcranial
administration
NIR
830
nm.
Our
results
showed
that
photobiomodulation
(PBM)
attenuated
deterioration
made
young,
but
not
rats,
while
both
exhibited
decreased
anxiety
(mania)-like
behavior
response
PBM.
PBM
had
an
inhibitory
effect
on
AChE,
enhanced
production
ACh,
ROS,
regulated
cell
apoptosis
factors
such
as
Bax
Bcl-2.
increased
mRNA
expression
BDNF
GLP-1
thus
facilitating
neuronal
survival
differentiation.
findings
also
revealed
age
exerts
additive
factor
assaults
produced
where
damages
2-month
less
severe
than
those
one.
In
conclusion,
seems
promote
longevity
cells
combating
elevating
neurotrophic
factors,
improving
performance.
provide
possible
candidate
insults
accompanying
aging
SD.
Advanced Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 2, 2024
Abstract
The
nervous
and
immune
systems
are
closely
interconnected,
influence
the
onset
progress
of
various
diseases.
Accordingly,
understanding
interaction
neural
system
becomes
very
important
for
treatment
intractable
diseases
with
analysis
therapeutic
mechanisms,
such
as
autoimmune
diseases,
neurodegenerative
cancers,
so
on.
conventional
immunomodulation
treatments
have
been
mainly
carried
out
by
drug
administration,
but
they
suffered
from
systemic
negative
side‐effects
only
limited
effects
on
specific
disease.
In
this
Perspective,
photonic
nanomaterials
devices
reviewed
discussed
digitally
controlled
neurostimulating
photomedicine
via
photobiomodulation
optogenetics
unique
viewpoint
neuro‐immune
cross‐talks.
prospects
perspectives
to
integrate
advanced
wearable
implantable
healthcare
also
provided
highlighted
revolutionize
strategies
systems,
optimize
protocols
futuristic
digital
photomedicine.
This
approach
will
fields
neurostimulation
regulation
further
clinical
applications.
Deleted Journal,
Journal Year:
2024,
Volume and Issue:
6(2), P. 550 - 577
Published: April 29, 2024
Antidepressants
are
among
the
most
used
medications
in
US,
with
significant
deleterious
effects
on
people’s
well-being.
At
any
given
time,
depression
impacts
approximately
1
10
Americans,
causing
wide
and
broad
societal
costs.
Interest
is
developing
for
non-pharmacological
treatments
preventative
measures.
We
summarize
literature
non-invasive
dietary
lifestyle
approaches
treating
depression.
This
review
aims
to
inform
future
research
treatment
programs
by
providing
an
evidentiary
summary
of
integrative
therapeutic
Journal of Alzheimer s Disease,
Journal Year:
2021,
Volume and Issue:
83(4), P. 1453 - 1469
Published: Sept. 3, 2021
Background:
Major
depressive
disorder
(MDD)
is
prevalent
and
has
significant
impact
on
individuals
society.
Cognitive
symptoms
are
frequent
in
MDD
insufficiently
treated
by
antidepressant
medications.
Transcranial
photobiomodulation
(t-PBM)
a
novel
device
therapy
which
shows
promise
as
an
pro-cognitive
treatment.
To
date,
despite
the
encouraging
results,
optimal
stimulation
parameters
of
t-PBM
to
treat
not
established,
clinical
studies
very
heterogeneous
terms
these
parameters.
While
literature
provides
guidance
appropriate
fluence
achieve
therapeutic
little
known
other
Objective:
evaluate
relationship
between
different
effect
t-PBM.
Methods:
We
reviewed
comorbid
with
diseases.
calculated
standardized
size
change
severity
before
after
we
performed
descriptive
analysis
papers.
Results:
The
greatest
sizes
for
were
found
using
pulse-wave
high
peak
irradiance
(but
low
average
irradiance)
over
large
skin
surface.
One
well-designed
sufficiently
powered,
double-blind,
sham-controlled
trial
indicated
that
small
surface
ineffective
depression.
Conclusion:
use
Alzheimer’s
disease
dementia
still
at
its
inception;
dosimetry
lessons
from
depression
might
serve
guidance.
Photobiomodulation Photomedicine and Laser Surgery,
Journal Year:
2023,
Volume and Issue:
41(3), P. 104 - 119
Published: March 1, 2023
Objective:
To
evaluate
relevant
clinical
outcomes
and
conclude
possible
mechanisms
of
intense
pulsed
light
(IPL)
in
eyelid
inflammation.
Background:
IPL
devices
were
primarily
applied
cutaneous
vascular
malformations
have
been
used
ocular
diseases
for
about
20
years,
mostly
including
meibomian
gland
dysfunction
(MGD),
blepharitis,
rosacea.
Recent
findings:
Seventy-two
original
researches
included,
57
MGD,
4
blepharitis
or
blepharitis-related
keratoconjunctivitis,
11
Dry
eye
symptoms,
(tear)
break-up
time
(BUT),
structure
and/or
functions
improved
most
patients,
but
production
reactive
oxygen
species
is
an
important
link
the
photobiomodulation
mediated
by
IPL,
which
can
influence
numerous
signal
pathways
to
achieve
anti-inflammatory,
anti-infective,
prodifferentiation
effects.
Conclusions:
The
evidence
suggests
that
effective
therapeutic
tool
patients
with
more
needed
other
indications.
Neurochemical Research,
Journal Year:
2023,
Volume and Issue:
49(4), P. 919 - 934
Published: Dec. 20, 2023
The
growing
prevalence
of
aged
sleep-deprived
nations
is
turning
into
a
pandemic
state.
Acute
sleep
deprivation
(SD)
accompanies
aging,
changing
the
hippocampal
cellular
pattern,
neurogenesis
pathway
expression,
and
aggravating
cognitive
deterioration.
present
study
investigated
ability
Near
Infra
Red
(NIR)
light
laser
to
ameliorate
impairment
induced
by
SD
in
young
senile
rats.
Wistar
rats
≤
2
months
(young)
≥
14
(senile)
were
for
72
h
with
or
without
transcranial
administration
NIR
830
nm.
Our
results
showed
that
photobiomodulation
(PBM)
attenuated
deterioration
made
young,
but
not
rats,
while
both
exhibited
decreased
anxiety
(mania)-like
behavior
response
PBM.
PBM
had
an
inhibitory
effect
on
AChE,
enhanced
production
ACh,
ROS,
regulated
cell
apoptosis
factors
such
as
Bax
Bcl-2.
increased
mRNA
expression
BDNF
GLP-1
thus
facilitating
neuronal
survival
differentiation.
findings
also
revealed
age
exerts
additive
factor
assaults
produced
where
damages
2-month
less
severe
than
those
one.
In
conclusion,
seems
promote
longevity
cells
combating
elevating
neurotrophic
factors,
improving
performance.
provide
possible
candidate
insults
accompanying
aging
SD.