Cureus, Journal Year: 2025, Volume and Issue: unknown
Published: May 9, 2025
Language: Английский
Cureus, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 30, 2025
Atrial fibrillation (AF) is the most common major cardiac rhythm disorder in adults and causes considerable morbidity mortality, particularly elderly patients. We present case of a 75-year-old female admitted for acute heart failure with history AF recurrent exacerbations. Despite aggressive medical management amiodarone diuretics, patient continued to deteriorate. The cardiology team recommended electrical cardioversion re-establish normal sinus rhythm. By doing so, developed flash pulmonary edema after procedure required immediate intubation mechanical ventilation. There was need tracheostomy facilitate prolonged ventilatory support some time. Over time, they were weaned off ventilator discharged home full recovery. This illustrates challenges managing an possible risks due cardioversion.
Language: Английский
Citations
0
Future Cardiology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 9
Published: Jan. 28, 2025
Decreased left atrial appendage emptying velocity (LAAV) is a marker for thrombus formation. This study evaluates the association between LAAV and inflammatory indices in non-valvular fibrillation (AF) patients. The population was 1428 patients with AF, 875 of whom enrolled. Based on LAAV, were divided into three groups 262 <25 cm/s, 360 25 to 55 253 >55 cm/s assess compare terms indices, including platelet-to-lymphocyte ratio, neutrophil-to-lymphocyte systemic immune inflammation index, neutrophil - platelet ratio white blood cell-to-platelet (WPR). There no statistical difference level groups, none them related (p > .05) except WPR weak negative correlation = 0.01, r -0.10). Patients lower found have higher age 0.001), decreased ventricular ejection fraction 0.001) greater volume index 0.001). did not show any AF WPR.
Language: Английский
Citations
0
Cureus, Journal Year: 2025, Volume and Issue: unknown
Published: March 19, 2025
Introduction and aim: Heart failure with preserved ejection fraction (HFpEF) is a significant clinical challenge, often coexisting atrial fibrillation (AF), which exacerbates patient outcomes by increasing risks of stroke, hospitalizations, mortality. Recent studies suggest that epicardial adipose tissue (EAT), metabolically active fat depot, may contribute to AF pathogenesis promoting remodeling fibrosis. This study aimed evaluate the relationship between EAT thickness in HFpEF patients. Materials methods: A total 110 patients were included, 20 (18.2%) having documented AF. was measured using transthoracic echocardiography, confirmed via electrocardiography. Results: Patients had significantly greater compared those without (8.3 ± 0.9 mm vs. 7.1 0.8 mm, p < 0.001). Receiver operating characteristic (ROC) analysis demonstrated strong predictor (AUC = 0.87, 0.001), cut-off value 7.5 achieving 89% sensitivity 75% specificity. Conclusion: These findings indicate increased independently associated patients, highlighting its potential as biomarker for risk stratification. Future should explore whether targeting could improve this high-risk population.
Language: Английский
Citations
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PeerJ, Journal Year: 2025, Volume and Issue: 13, P. e19173 - e19173
Published: March 24, 2025
Background To investigate the effect of degree atrial fibrosis on clot burden score (CBS) and physicochemical properties in patients with acute ischaemic stroke (AIS) due to non-valvular fibrillation (NVAF). Methods A total 117 AIS NVAF attending Department Cardiovascular Medicine Cerebrovascular Diagnostic Treatment Centre between August 2021 May 2024 were included study. Baseline clinical data, biochemical indexes, imaging data collected, divided into 93 cases CBS (score 0–6) group 24 7–10) according CBS. signifies higher burden. The enzyme-linked immunosorbent assay was used measure concentration galactaglutinin-3 (gal-3) transforming growth factor (TGF-β1) serum patients, PTFV1 collected by 12-lead electrocardiogram, differences different groups risk factors analysed. analyse collateral circulation stroke, 31 good (grade 3–4) 86 poor 0–2) digital subtraction angiography (DSA) images. cerebral thrombus from 60 who underwent mechanical thrombectomy. content erythrocyte, fibrin/platelets leukocytes analysed Mathew’s scarlet blue staining, density measured computed tomography (CT). Results this study, proportion hypertensive chronic (CAF), B-type natriuretic peptide (BNP), neutrophil/lymphocyte ratio (NLR), D-dimer, uric acid concentration, < −0.03 mm s, gal-3, TGF-β1 as compared ( P -value 0.05). Hypertension, CAF, homocysteine, NLR, acid, TGF-β1, for development high (AF), hypertension CAF most important occurrence AF independent combined gal-3 circulation, indexes not associated pathological composition density. Conclusions Atrial increases but does significantly correlate thrombus.
Language: Английский
Citations
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Cureus, Journal Year: 2025, Volume and Issue: unknown
Published: May 9, 2025
Language: Английский
Citations
0