Retracted: COVID‐19 mortality and its predictors in the elderly: A systematic review

Health Science Reports, Journal Year: 2022, Volume and Issue: 5(3)

Published: May 1, 2022

Abstract Background and Aims Older people have higher rates of comorbidities may experience more severe inflammatory responses; therefore, are at risk death. Herein, we aimed to systematically review the mortality in coronavirus disease 2019 (COVID‐19) patients its predictors this age group. Methods We searched PubMed, Web Science, Science Direct using relevant keywords. Retrieved records underwent a two‐step screening process consisting title/abstract full‐text screenings identify eligible studies. Results Summarizing findings 35 studies demonstrated that older compared younger population. A articles revealed increasing age, body mass index, male gender, dementia, impairment or dependency daily activities, presence consolidations on chest X‐ray, hypoxemic respiratory failure, lower oxygen saturation admission were factors for High d ‐dimer levels, 25‐hydroxy vitamin D serum deficiencies, high C‐reactive protein (≥5 mg/L) levels plus any other abnormalities lymphocyte, blood urea nitrogen lactate dehydrogenase, platelet count poor prognosis elderly. Studies also shown previous treatment with renin–angiotensin–aldosterone system inhibitors, pharmacological treatments disorders, antibiotics, corticosteroids, K antagonist, antihistamines, azithromycin, Itolizumab (an anti‐CD6 monoclonal antibody) combination antivirals reduces COVID‐19 worsening mortality. Vaccination against seasonal influenza might reduce Conclusion Overall, critical consideration is necessary care management aged population considering drastic contrasts manifestation groups. Mortality from independently associated patient's age. Elderly vulnerable outcomes. Thus, strict preventive measures, timely diagnosis, aggressive therapeutic/nontherapeutic great importance acute distress syndrome complications people.

Language: Английский

---

The impacts of COVID-19 pandemic on service delivery and treatment outcomes in people living with HIV: a systematic review

AIDS Research and Therapy, Journal Year: 2023, Volume and Issue: 20(1)

Published: Jan. 6, 2023

Abstract Introduction The COVID-19 epidemic and various control mitigation measures to combat the widespread outbreak of disease may affect other parts health care systems. There is a concern that pandemic could disrupt HIV services. Therefore, this study aimed systematically evaluate effect on service delivery treatment outcomes in people with HIV. Methods In study, systematic search was conducted using keywords online databases including Scopus, PubMed, Web Science, Cochrane databases. retrieved articles underwent two-step title/abstract full-text review process, eligible papers were selected included qualitative synthesis. Result We 16 studies out 529 records met inclusion criteria for review. Study populations either HIV-positive patients or clinics healthcare providers. Most focused adhering obtaining medication attending clinical appointments their decrement during pandemic. Other aspects (alternative settings, viral suppression, psychological care, etc.) discussed lesser extent by studies. Conclusion Interruption in-person visits medical follow-up services, loss adherence treatment, subsequent increase mortality due complications PLHIV have led growing concerns. challenges disorders such as anxiety depression, an substance abuse, rise experienced stigma discrimination. However, use telemedicine some countries helps alleviate situation recommended similar settings future.

Language: Английский

---

COVID-19 mortality in patients with immunodeficiency and its predictors: a systematic review

European journal of medical research, Journal Year: 2022, Volume and Issue: 27(1)

Published: Oct. 8, 2022

Abstract Introduction Patients with immunodeficiency are usually more prone to worse outcomes of infectious diseases. However, there some disagreements in the context COVID-19, for example, patients human virus (HIV). Herein, we aimed systematically review risk and predictors COVID-19 mortality people primary or secondary immunodeficiency. Methods PubMed, Scopus, Web Science, Science Direct were searched. We followed a two-step screening process identify eligible results. first reviewed title abstract records unqualified studies removed. Then, their full texts evaluated based on coherence purpose inclusion/exclusion criteria, those qualitative synthesis included. Results Twenty-two articles included, which investigated total 109,326 immunodeficiencies. Three pediatric infant population, while other conducted adult population. Overall, both conflicted as reported higher mentioned lower rates Conclusions two points view types The is classical viewpoint that all immunodeficient at infection leading rate. second found might play less important even an inverse role by lowering severity inflammatory response. it take note comorbidities, such DM, HTN, CAD, ESRD, history respiratory infection, etc., demographic factors, obesity age > 70 years, they appear influence rate, especially

Language: Английский

---

The effect of macronutrient and micronutrient supplements on COVID-19: an umbrella review

Journal of Health Population and Nutrition, Journal Year: 2024, Volume and Issue: 43(1)

Published: Jan. 29, 2024

Abstract Background and aims A healthy diet play an important role in the prevention even treatment of various diseases. Proper nutrition plays boosting immune system. These include consumption macronutrients such as proteins, lipids, carbohydrates, also micronutrients including vitamins. Here, we aimed to systematically review effects on COVID-19. Methods We searched databases PubMed, Scopus, Embase, Web Science December 23, 2023. The records were downloaded into EndNote file, duplicates removed, studies underwent a two-phase screening process based their title/abstracts full texts. included articles screened inclusion exclusion criteria. English systematic reviews meta-analyses that concurred with aim our study. selected assessed by Cochrane's Risk Bias Systematic Reviews for quality check. data eligible extracted pre-designed word table used qualitative synthesis. Results total 28 this Most have shown are effective morbidity mortality controlling viral respiratory infections COVID-19 but some sometimes not severity. On other hand, calcifediol was far most successful agent reducing intensive care needs between studies. Conclusion Individuals without malnutrition had reduced risk SARS-CoV-2 infection severe disease. administration Vitamin D is patients. Patients vitamin deficiency more prone experience infection, they at higher morbidities mortality. Other A, B, Zinc showed benefits patients C no efficacy management intravenous form or high doses.

Language: Английский

---

COVID-19 Vaccines' Protection Over Time and the Need for Booster Doses; a Systematic Review.

PubMed, Journal Year: 2022, Volume and Issue: 10(1), P. e53 - e53

Published: Jan. 1, 2022

Controversies existed regarding the duration of COVID-19 vaccines' protection and whether receiving usual vaccine doses would be sufficient for long-term immunity. Therefore, we aimed to systematically review studies three months after getting fully vaccinated assess need booster doses.The relevant literature was searched using a combination keywords on online databases PubMed, Scopus, Web Science, Cochrane September 17th, 2021. The records were downloaded duplicates removed. Then, evaluated in two-step process, consisting title/abstract full-text screening processes, eligible selected qualitative synthesis. We only included original that efficacy immunity vaccines full vaccination. This adhered Preferred Reporting Items Systematic Reviews Meta-analyses (PRISMA) statement ensure reliability results.Out 797 retrieved records, 12 included, 10 mRNA-based two inactivated vaccines. majority observed acceptable antibody titers most participants even 6 months; however,it appeared could also decrease considerable portion people. Due reduction protection, several suggested administering dose, especially older patients those with underlying conditions, such as immunodeficiencies.Studies indicated decreases over time, making people more susceptible contracting disease. Besides, new variants are emerging, omicron variant is continuing spread escape from immune system, indicating importance dose.

Language: Английский

---

Incidence of Symptomatic COVID-19 in Unvaccinated Patients Within One Month After Elective Total Joint Arthroplasty: A Multicenter Study

Arthroplasty Today, Journal Year: 2022, Volume and Issue: 14, P. 110 - 115

Published: Jan. 24, 2022

The safety of continuing total joint arthroplasty (TJA), as an elective procedure, during the pandemic is controversial. present study aimed to investigate incidence symptomatic coronavirus disease 2019 (COVID-19) and its related risk factors in unvaccinated patients after TJA within 1 month discharge 2 large cities our country.The prospective included all admitted 3 hospitals, located Tehran Isfahan, highly populated Iran, from April 1, 2020, 2021, for TJA. Urgent (traumatic fractures) were excluded. primary outcome was COVID-19 that diagnosed using severe acute respiratory syndrome (SARS-CoV-2) reverse transcription polymerase chain reaction test. Afterward, population compared with general estimate pandemic.From 1007 undergoing TJA, 755 met inclusion criteria. None vaccinated against COVID-19. Among them, 18 (2.4%) developed discharge. In same time interval, 2.2% these cities, which similar reported population. Of who positive COVID-19, 4 hospitalized, them intensive care unit; however, no mortality reported.The will be a safe procedure if preventive protocols are followed strictly.

Language: Английский

---

Global knowledge, attitude, and practice towards COVID-19 among pregnant women: a systematic review and meta-analysis

BMC Pregnancy and Childbirth, Journal Year: 2023, Volume and Issue: 23(1)

Published: April 22, 2023

Abstract Background Pregnant women form a specially vulnerable group due to unique changes in pregnancy, leading higher risk of getting severe infection. As COVID-19 increases the preeclampsia, preterm delivery, gestational diabetes, and low birth weight there is need enhance pregnant women’s knowledge, attitudes, practices prevent these complications. This systematic review meta-analysis aimed determine their levels practice (KAP) regarding at global level. Methods The literature search was conducted English language, including Google Scholar, Scopus, PubMed/MEDLINE, Science Direct, Web Science, EMBASE, Springer, ProQuest, from occurrence pandemic until September 2022. We used Newcastle Ottawa scale for cross-sectional studies checklist evaluate bias studies. Data were extracted by Microsoft Excel spreadsheet analyzed STATA software version 14. also employed Cochran Q statistics assess heterogeneity utilized Inverse variance random-effects models estimate pooled level KAP towards infection prevention. Results Based on preferred reporting items reviews meta-analyses (PRISMA) inclusion criteria, 53 qualified acquired several countries. In total, 51 articles (17,319 participants) 15 (6,509 24 (11,032 included this meta-analysis. good positive attitude, appropriate estimated 59%(95%CI: 52–66%), 57%(95%CI: 42–72%), 53%(95%CI: 41–65%), respectively. According subgroup analysis, 61%(95%CI: 49–72), 52%(95%CI: 30–74), 50%(95%CI: 39–60), respectively, Africa, 58.8%(95%CI: 49.2–68.4), 60%(95%CI: 41–80) 60% (95%CI: 41–78), Asia. Conclusion Knowledge, prevention low. It suggested that health education programs empowerment communities, especially women, about continue with better planning. For future studies, we propose investigate countries other continents geographical regions.

Language: Английский

---

Multimorbidity and frailty are associated with poorer SARS-CoV-2-related outcomes: systematic review of population-based studies

Aging Clinical and Experimental Research, Journal Year: 2024, Volume and Issue: 36(1)

Published: Feb. 14, 2024

Abstract Background Estimating the risks and impacts of COVID-19 for different health groups at population level is essential orienting public measures. Adopting a population-based approach, we conducted systematic review to explore: (1) etiological role multimorbidity frailty in developing SARS-CoV-2 infection COVID-19-related short-term outcomes; (2) prognostic short- long-term outcomes. This presents state evidence early years pandemic. It was within European Union Horizon 2020 program (No: 101018317); Prospero registration: CRD42021249444. Methods PubMed, Embase, World Health Organisation Global literature on coronavirus disease, PsycINFO were searched between January 7 April 2021 1 February 2022 frailty. Quantitative peer-reviewed studies published English with population-representative samples validated tools considered. Results Overall, 9,701 records screened by title/abstract 267 full text. Finally, 14 retained (etiological role, n = 2; prognostic, 13) 5 4). Only outcomes, mainly mortality, identified. An elevated likelihood poorer outcomes associated an increasing number diseases, higher Charlson Comorbidity Index, disease combinations, level. Discussion Future studies, which include effects recent virus variants, repeated exposure vaccination, will be useful comparing possible evolution associations observed earlier waves.

Language: Английский

---

Hearing loss and COVID-19: an umbrella review

European Archives of Oto-Rhino-Laryngology, Journal Year: 2023, Volume and Issue: 280(8), P. 3515 - 3528

Published: April 24, 2023

Language: Английский

---

Impact of COVID-19 on emotional and behavioral problems among preschool children: a meta-analysis

BMC Pediatrics, Journal Year: 2024, Volume and Issue: 24(1)

Published: July 16, 2024

The impact of the Coronavirus Disease 2019 (COVID-19) on society is continuous, resulting in negative psychological consequences. Given vulnerability and sensitivity to environment among preschool children, their emotional behavioral problems deserve more attention. current study aimed explore epidemic children's mental health by determining pooled prevalence amidst pandemic reveal potential reasons for variations between studies. Published studies were searched Embase, PubMed, ProQuest, PsycINFO, Web Science, CNKI, Wanfang. Based inclusion criteria outlined this study, a total 10 encompassing 38,059 participants incorporated. Employing random-effect model estimating problems, results revealed rate 24.3% (95% CI, 0.15-0.38; I²=99.9%) children. This surpasses pre-outbreak observed different countries, signifying detrimental influence well-being preschoolers. Therefore, care recovery are essential vulnerable group during after public crisis. Specific children expected be researched future provide targeted guidance intervention.

Language: Английский

---