Correlates of mental health of people living with HIV co-infected with SARS-CoV-2: findings from the COVIDHIV study in France

Frontiers in Psychiatry, Journal Year: 2025, Volume and Issue: 15

Published: Jan. 3, 2025

The COVID-19 pandemic has severely affected vulnerable populations, especially individuals living with HIV/AIDS (PLWHA). convergence of and presents unique challenges, exacerbating existing health concerns magnifying the strain on already grappling compromised immune systems. This study aimed to investigate mental well-being repercussions faced by PLWHA co-infected SARS-CoV-2 in France. COVIDHIV is a French multicenter cohort SARS-CoV-2, which collected sociodemographic, clinical, data. Anxiety depression symptoms post-traumatic stress disorder (PTSD) were assessed Hospital Depression Scale (HADS) PTSD Checklist (PCL-S), respectively. Multivariable logistic regression was performed identify factors associated outcomes at inclusion cohort. Of 397 participants included, 64.7% male. mean age 51.6 (± 11.8) years. prevalence 33.5% ([95%CI: 28.5-39.0%]) for anxiety, 21.0% ([16.8-25.9%]) depression, 12.2% ([8.9-16.5%]) PTSD. In multivariable adjusted sex, wave duration between confirmation enrolment, (adjusted odds-ratio (aOR): 0.97 [0.95-0.99]), being professionally active (0.43 [0.25-0.75]), number self-reported (1.17 [1.11-1.24]) anxiety. Being (0.34 [0.18-0.65]), couple (0.52 [0.20-0.98]), (1.15 [1.08-1.22]), hospitalization (3.35 [1.34-8.33]) depression. (1.27 [1.16-1.41]), psychiatric disorders (4.04 [1.48-11.11]), perceived vulnerability (4.53 [1.69-14.60]) challenging issue among needs be closely monitored people chronic disease such as HIV. findings underscore urgent need targeted support interventions tailored address facing dual burden COVID-19.

Language: Английский

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Access to Hearing Healthcare and Barriers Among United States Veterans: A Survey‐Based Study

OTO Open, Journal Year: 2025, Volume and Issue: 9(1)

Published: Jan. 1, 2025

Abstract Objective We investigated use of hearing care among US veterans and explore motivations, barriers, adherence to healthcare. Study Design Cross‐sectional online survey. Setting Veterans. Methods This cross‐sectional, survey‐based study included 287 respondents who identified themselves as on ResearchMatch (NIH‐sponsored national registry research volunteers). Questions regarding loss, tinnitus, care, facilitators/barriers were asked. Descriptive statistics utilized for data analysis. Results In this cohort, the rate self‐reported loss tinnitus 61.0% 74.2%, respectively. Among these, 66.9% those with 36.2% reported seeking care. Most important motivators (average 1‐5 Likert scale) personal importance (4.0; SD = 1.1), difficulty others (3.6; degree (3.3; 1.1). common barriers uncertainty reach out (42.9%), inability get time off work (34.3%), nervousness about seeing a provider (28.6%). Common reasons decline aids reporting that was not bad enough (72.2%) afford aid (55.6%). Conclusion many sought though still exist, including how access appropriate being too far from provider, challenges cost. Future studies should investigate methods alleviate these internal external emphasize

Language: Английский

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Public Knowledge and Factors Associated With Familiarity of Treatments for Rhinosinusitis

OTO Open, Journal Year: 2025, Volume and Issue: 9(1)

Published: Jan. 1, 2025

Abstract Objective Rhinosinusitis is a common otolaryngologic condition with many over‐the‐counter (OTC), prescription, and surgical treatment options. This study seeks to evaluate public familiarity treatments for rhinosinusitis. Study Design Cross‐sectional survey Setting US adult (≥18 years) online respondents Methods A cross‐sectional was administered adults via ResearchMatch. Questions included demographic questionnaire, validated nasal obstruction surveys, personal history of chronic rhinosinusitis (CRS), as well various (5‐point Likert scale). Descriptive statistics were utilized describe results, multivariable ordinal regression factors associated knowledge any treatments. Results The cohort (n = 1086) primarily female (75.7%), white (80.3%), married (47.5%), college educated (36.6%). Highest rates reported antihistamines (80%), decongestants corticosteroids (78%). Factors age (odds ratio [OR]: 0.99 [95% confidence interval [CI]: 0.98‐0.99]), literacy score (OR: 0.76 CI: 0.71‐0.82]), CRS diagnosis 2.91 2.25‐3.75]), symptomatic score. OTC gender 2.40 1.82‐3.16]), 0.77 0.72‐0.83]), 2.94 2.25‐3.83]), Conclusion Individuals at risk having lower options include males, older individuals, those health literacy. Future studies should the impact that primary care provider has on outcomes

Language: Английский

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Overall Survival With Palbociclib and Aromatase Inhibitor Versus Aromatase Inhibitor Alone in Older Patients With HR+/HER2− Metastatic Breast Cancer

Cancer Medicine, Journal Year: 2025, Volume and Issue: 14(7)

Published: March 27, 2025

ABSTRACT Introduction Cyclin‐dependent kinase 4/6 inhibitors (CDK4/6is) in combination with endocrine therapy are the current standard of care for first‐line (1L) treatment hormone receptor–positive and human epidermal growth factor receptor 2–negative (HR+/HER2–) metastatic breast cancer (mBC). To investigate effectiveness palbociclib, first‐in‐class CDK4/6i, plus an aromatase inhibitor (AI) older patients, we compared overall survival (OS) a Medicare population treated 1L palbociclib + AI versus alone. Methods Patients aged ≥ 65 years who were diagnosed de novo HR+/HER2– mBC from 2015 to 2019 identified Surveillance, Epidemiology, End Results (SEER)–linked database eligible if they initiated or The primary endpoint was OS. Stabilized inverse probability weighting (sIPTW) used balance baseline patient characteristics. Of 779 296 received 483 alone as treatment. After sIPTW, median follow‐up 23.1 months 18.2 Adjusted OS longer (sIPTW: 37.6 vs. 25.5 months, HR = 0.73 [95% CI, 0.59–0.91]). In multivariable Cox proportional hazards regression, patients had 39% lower risk death (HR 0.61 0.48–0.77]). Conclusion routine US clinical practice, associated significantly prolonged mBC, adding growing body evidence on benefit this population. Trial Registration ClinicalTrials.gov identifier: NCT06086340

Language: Английский

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Divine Intervention or Medical Consultation? Exploring Health-seeking Choices in Ghana's Religious Gated Communities in Ghana

Published: May 12, 2025

This study investigates the health-seeking behaviors of residents in religious gated communities Ghana, focusing on relationship between beliefs and healthcare decisions. Using qualitative research design, explores knowledge, perceptions, practices individuals Agogo (Saviour Church Ghana) New Winneba (Chapers). Fifteen participants were interviewed data analyzed thematically. Residents’ understanding health encompass physical fitness, absence disease, optimal bodily functioning. Healthcare is perceived both as daily self-care formal medical interventions. Factors influencing include income, services accessibility, severity illness, beliefs. Some attribute illness to spiritual causes prioritize faith-based healing, or leaders’ guidance over conventional treatment. There is, therefore, need for public strategies address unique socioeconomic, cultural, dynamics these improve outcomes.

Language: Английский

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Healthcare Utilization and Adherence to Treatment Recommendations among Children with Type 1 Diabetes in Poland during the COVID-19 Pandemic

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(8), P. 4798 - 4798

Published: April 15, 2022

Type 1 diabetes mellitus (T1D) is, next to obesity and asthma, the most common chronic disease in children Poland. The results of T1D treatment strongly depend on patient's compliance with therapeutic recommendations, which entails use necessary health services. Based a retrospective analysis data services provided 2016-2020 over 15.5 thousand patients Poland, we assessed actual model current guidelines. It was found that only about 50% received number consultations corresponding recognized standards, 15% remaining outside public healthcare system. In case many outpatient (ophthalmological, neurological, mental health), extremely low-one order magnitude lower than general population dropped even 2020. This shows needs are not being met within COVID-19 pandemic caused significant limitations access Compared pre-pandemic period there decrease (-27% compared 2019) hospitalizations, substantial increase (+22% diabetic ketoacidoses (DKA) cases. proportion hospitalizations by DKA rose 8.9% 7.3% 2019.

Language: Английский

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The Impact of the COVID Pandemic on the Incidence of Presentations with Cancer-Related Symptoms in Primary Care

Cancers, Journal Year: 2022, Volume and Issue: 14(21), P. 5353 - 5353

Published: Oct. 30, 2022

Introduction: In the Netherlands, onset of coronavirus pandemic saw shifts in primary health service provision away from physical consultations, cancer-screening programs were temporarily halted, and government messaging focused on remaining at home. March April 2020, weekly cancer diagnoses decreased to 73% their pre-COVID levels, 39% for skin cancer. This study aims explore effect COVID patient presentations cancer-related symptoms care The Netherlands. Methods: Retrospective cohort using routine clinical data. Monthly incidences five databases Netherlands analysed 2018 February 2021. Results: Data demonstrated reductions incidence symptom during first wave (March-June 2020) -34% (95% CI: -43 -23%) all combined. second (October 2020-February 2021) there was no change observed (-8%, 95% CI -20% 6%). Alarm-symptoms decreases with subsequent that continued rise wave, such as: wave: breast lump -17% -27 -6%) haematuria -15% -24% -6%); rectal bleeding +14% 0 30%) 2 27%). Presentations common non-alarm as tiredness naevus in-cidences 45% -55% -33%) 37% -47% -25%). reduced by 20% -33% -3%). Subgroup analy-sis did not demonstrate difference according sex, age groups, comorbidity status, or previous history Conclusions: These data describe large-scale avoidance increase until end year many symptoms, suggestive substantial numbers patients delayed presenting care. For those who had underlying cancer, this may have impacted stage diagnosis, treatment, mortality.

Language: Английский

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Measuring the Impact of the COVID-19 Pandemic on Health Behaviors and Health Care Utilization in Rural and Urban Patients with Cancer and Cancer Survivors

Cancer Research Communications, Journal Year: 2023, Volume and Issue: 3(2), P. 215 - 222

Published: Jan. 26, 2023

Healthcare access and health behaviors differ between those living in urban rural communities contribute to inequitable cancer outcomes. The COVID-19 pandemic led significant disruptions daily life healthcare delivery. This cross-sectional survey aimed measure the impact of on patients survivors, comparing outcomes for respondents. Survey was administered from January 2021-June 2021 or survivors (treated within last 5 years) at one six centers Washington Idaho. Respondent ZIP code used assess rurality using Rural-Urban Commuting Area designation. 515 (43.5% contacted) 146 (40% participated. Few differences were noted. Rural residents older (69.2 years vs. 66.9 years). respondents had higher mean alcohol consumption than (4.4 drinks per week 2.7 week). 12.2% who reported drinking 30 days also increased since start pandemic, with no difference 38.5% decreased physical activity. 20.5% cancelling delaying care due pandemic. Delays services worsening may poorer outcomes, few survivors.

Language: Английский

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Dental Utilization in a Pediatric Emergency Department and Urgent Care Centers Before, During, and After Shutdown of a Pediatric Dental Clinic During the COVID-19 Pandemic, 2019-2021

Public Health Reports, Journal Year: 2023, Volume and Issue: 138(3), P. 493 - 499

Published: Feb. 3, 2023

Limited data are available on how the closure of pediatric dental clinics because COVID-19 pandemic affected hospital emergency department (ED) visits in United States. We evaluated changes dental-related at a ED and associated urgent care centers (UCCs) after shutdown large clinic pandemic.We conducted single-center retrospective medical record review 811 patients aged 0 to 17 years who presented or UCC Rady Children's Hospital-San Diego for concerns from March 19, 2019, through January 17, 2021. Patients were classified into 3 periods: before shutdown, during shutdown. collected demographic characteristics; International Classification Diseases, Tenth Revision codes; diagnosis; treatment; test results. compared frequency proportion seen concerns, diagnosis, treatment periods.The doubled (0.7%) was 1.5 times higher (0.6%) with (0.4%; P < .001). Significantly more EDs than UCCs (P = .005). During admission antibiotic increased significantly 6.5% 7.9%, respectively, (2.8%; .022), nonaerosolized procedures ED/UCC discharge 13.4% 9.3%, (6.2%; .015).Mitigating future closures offices is important given shifted burden ED.

Language: Английский

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Delayed Medical Care of Underserved Middle-Aged and Older African Americans with Chronic Disease during COVID-19 Pandemic

Healthcare, Journal Year: 2023, Volume and Issue: 11(4), P. 595 - 595

Published: Feb. 16, 2023

Background: While African American middle-aged and older adults with chronic disease are particularly vulnerable during the COVID-19 pandemic, it is unknown which subgroups of this population may delay seeking care. The aim study was to examine demographic, socioeconomic, COVID-19-related, health-related factors that correlate delayed care in disease. Methods: In cross-sectional study, 150 who had at least one were recruited from faith-based organizations. We measured following exploratory variables: demographic (age gender), socioeconomic status (education), marital status, number diseases, depressive symptoms, financial strain, health literacy, vaccination history, diagnosis knowledge, perceived threat. outcome Results: According Poisson log-linear regression, higher level education, symptoms associated a Age, gender, threat, literacy not correlated Discussion: Given healthcare needs terms multiple medical diseases symptomatology but COVID-19-related constructs (i.e., threat) care, there need for programs interventions assist seek they need. More research needed understand why educational attainment more illness.

Language: Английский

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