Validation of a Rapid Remote Digital Test for Impaired Cognition using Clinical Dementia Rating and Mini-Mental State Examination: An Observational Research Study DOI Creative Commons
Ali Alim‐Marvasti, Narayan Kuleindiren, Kirsten Harvey

et al.

Research Square (Research Square), Journal Year: 2022, Volume and Issue: unknown

Published: June 30, 2022

Abstract Background The Clinical Dementia Rating (CDR) and Mini-Mental State Examination (MMSE) are useful screening tools for mild cognitive impairment (MCI). However, these tests require qualified in-person supervision take up to 60 or 15 minutes complete respectively. We have developed a digital test (M-CogScore) that can be completed remotely in under 5 without supervision. set out validate M-CogScore head-to-head comparisons with CDR MMSE. Methods To ascertain the validity of M-CogScore, we enrolled participants as healthy controls impaired cognition matched age, sex, education. Participants 30-item paper MMSE Second Edition Standard Version (MMSE-2-SV), CDR, smartphone-based M-CogScore. is based on time-normalised scores from smartphone adapted stroop (M-Stroop), digit-symbols (M-Symbols), delayed recall (M-Memory). used Pearson’s correlation coefficient determine convergent between MMSE-2, non-parametric compare diagnosis (CDR 0.5 1). was compared MMSE-2-SV using area receiver operating characteristic curves (AUC) corresponding optimal cut-offs. Results 72 all three tests. correlated both MMSE-2 (r=0.66, p <0.0001) (Mann Whitney U 187, <0.001). achieved an AUC 0.85 (95% bootstrapped CI [0.80, 0.91]) when differentiating normal cognition, 0.78 [0.72, 0.84] ( =0.21) Conclusion significantly established including MMSE-2-SV. taken supervision, automatically scored, has less ceiling effect than MMSE, takes time complete. Digital such desirable aid rapid remote clinical evaluations.

Language: Английский

Tele-Neuropsychology: From Science to Policy to Practice DOI Creative Commons
Scott A. Sperling, Shawn K. Acheson, Joshua T. Fox‐Fuller

et al.

Archives of Clinical Neuropsychology, Journal Year: 2023, Volume and Issue: 39(2), P. 227 - 248

Published: Sept. 15, 2023

The primary aim of this paper is to accelerate the number randomized experimental studies reliability and validity in-home tele-neuropsychological testing (tele-np-t).

Language: Английский

Citations

14

Study protocol: How does cognitive flexibility relate to other executive functions and learning in healthy young adults? DOI Creative Commons
Ke Tong,

Yuan Ni Chan,

Xiaoqin Cheng

et al.

PLoS ONE, Journal Year: 2023, Volume and Issue: 18(7), P. e0286208 - e0286208

Published: July 20, 2023

Cognitive flexibility (CF) enables individuals to readily shift from one concept or mode of practice/thoughts another in response changes the environment and feedback, making CF vital optimise success obtaining goals. However, how relates other executive functions (e.g., working memory, inhibition), mental abilities creativity, literacy, numeracy, intelligence, structure learning), social factors multilingualism, tolerance uncertainty, perceived support, decision-making) is less well understood. The current study aims (1) establish construct validity relation function skills (2) elucidate specific relationships between CF, learning, career decision planning, life skills.

Language: Английский

Citations

12

Measuring Cognitive Impairments Associated With Schizophrenia in Clinical Practice: Overview of Current Challenges and Future Opportunities DOI Creative Commons
Keith H. Nuechterlein, Henry A. Nasrallah, Dawn I. Velligan

et al.

Schizophrenia Bulletin, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 1, 2024

Abstract Background Cognitive impairment associated with schizophrenia (CIAS) negatively impacts daily functioning, quality of life, and recovery, yet effective pharmacotherapies practical assessments for clinical practice are lacking. Despite the pivotal progress made establishment Measurement Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Battery (MCCB) research, implementation full MCCB is too time-consuming cost-ineffective most clinicians practice. Study Design Here we discuss current relation delivery format (interview-based performance-based), validity, ease use patients, reliability/reproducibility, cost-effectiveness, suitability implementation. Key challenges future opportunities improving cognitive also presented. results Current that require 30 min complete would have value settings, but staff training time required might preclude their application settings. Initial profiling deficits may about assist selection evidence-based treatments; follow-up monitoring brief (10–15 duration) detect treatment-related effects on global cognition complement this approach. Guidance validated tests strategic treatment CIAS necessary. Conclusions With increased advancements technology-based remote assessments, development formats in-person assessment, necessary models infrastructure implementation, likely be increasing relevance

Language: Английский

Citations

2

Remote Testing of Reading Comprehension in 8-Year-Old Children: Mode and Setting Effects DOI Creative Commons
Timo Gnambs, Wolfgang Lenhard

Assessment, Journal Year: 2023, Volume and Issue: 31(2), P. 248 - 262

Published: March 8, 2023

Proctored remote testing of cognitive abilities in the private homes test-takers is becoming an increasingly popular alternative to standard psychological assessments test centers or classrooms. Because these tests are administered under less standardized conditions, differences computer devices situational contexts might contribute measurement biases that impede fair comparisons between test-takers. it unclear whether be a feasible assessment approach for young children, present study ( N = 1,590) evaluated reading comprehension children at age 8 years. To disentangle mode from setting effects, finished either classroom on paper remotely tablets laptops. Analyses differential response functioning found notable conditions selected items. However, scores were largely negligible. Only with below-average small effects on-site and observed. Moreover, effort was higher three computerized versions, among which, most strongly resembled condition. Overall, results suggest that, average, even introduces little bias.

Language: Английский

Citations

6

Cognitive inflexibility, obsessive-compulsive symptoms and traits and poor post-pandemic adjustment DOI Creative Commons
Ana Maria Frota Lisbôa Pereira de Souza, Luca Pellegrini, Naomi Fineberg

et al.

Neuroscience Applied, Journal Year: 2024, Volume and Issue: 3, P. 104073 - 104073

Published: Jan. 1, 2024

The ability to flexibly adapt thoughts and behaviours represents a fundamental attribute for behavioural success. Impairments in aspects of cognitive flexibility are found as transdiagnostic latent phenotypes obsessive-compulsive symptomatology present within range mental disorders the population at large. In this narrative review, we focus on attentional set-shifting aspect inflexibility, which has been largely investigated context spectrum is thought underpin perseverative symptomatology. We appraise published literature relating putative neurobiological mechanisms, methods assessment, interventional approaches, health wellbeing impacts. discuss critical knowledge gaps, promising new research avenues, potential approaches from clinical public perspective. conclude that inflexibility relevance clinicians terms understanding outcomes tailoring personalised forms treatments, professionals rigid attitudes adjustment current post-pandemic environment.

Language: Английский

Citations

1

Cut-off point development for the Everyday Memory Questionnaire – Revised in perimenopausal women DOI Creative Commons
Chen Zhu, Elizabeth Thomas, Qi Li

et al.

Climacteric, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 10

Published: Sept. 26, 2024

Subjective cognitive complaints have been reported in women during perimenopause and the Everyday Memory Questionnaire - Revised (EMQ-R) has recently evaluated as a standardized instrument to measure subjective changes. The purpose of this study was identify potential cut-off points for EMQ-R retrieval subscale attentional subscale, assess validity these detecting objective changes associated with complaints.

Language: Английский

Citations

1

Individual differences in L1 and L2 anaphora resolution: effects of implicit prosodic cues and working memory DOI Creative Commons
Andromachi Tsoukala, Margreet Vogelzang, Ianthi Maria Tsimpli

et al.

Applied Psycholinguistics, Journal Year: 2024, Volume and Issue: 45(5), P. 834 - 872

Published: Sept. 1, 2024

Abstract The present experimental studies shed light on effects of implicit prosodic cues anaphora resolution as well how these differ both within and between L1 L2 speaker groups. In two self-paced reading studies, participants read poem-like texts that contained anaphoric ambiguity. These stimuli were designed to include a rhyming scheme meter either regular or disrupted. We expected rhyme cue nonsubject pronoun antecedent (in the regularly metered version texts) induce competition in speakers cause them adapt their interpretative preferences processing strategies; yet, for we hypothesized would not be observed they attenuated. Additionally, examined whether comprehender-dependent factors modulate each group. tested memory-related tasks. also measured speakers’ print exposure L2ers’ proficiency English. Results revealed L1–L2 dissimilarities behavior, equally sensitive introduced. examination measures provided evidence within-group differences between-group parallels: higher working memory groups modulated resolution, although there was no additional influence context.

Language: Английский

Citations

1

In-person versus virtual administration of the American College of Rheumatology gold standard cognitive battery in systemic lupus erythematosus: Are they interchangeable? DOI Creative Commons

ML Barraclough,

JP Diaz-Martinez,

Andrea Knight

et al.

Lupus, Journal Year: 2023, Volume and Issue: 32(6), P. 737 - 745

Published: April 10, 2023

During the COVID-19 pandemic, many research studies were adapted, including our longitudinal study examining cognitive impairment (CI) in systemic lupus erythematosus (SLE). Cognitive testing was switched from in-person to virtual. This analysis aimed determine if administration method (in-person vs. virtual) of ACR-neuropsychological battery (ACR-NB) affected participant performance and classification.Data multi-visit, SLE CI included demographic, clinical, psychiatric characteristics, modified ACR-NB. Three analyses undertaken for performance: (1) all visits, (2) non-CI group visits only (3) intra-individual comparisons. A retrospective preferences questionnaire given participants who completed ACR-NB both virtually.We analysed 328 had 801 (696 105 virtual). Demographic, characteristics comparable except ethnicity, anxiety disease-related damage. Across three comparisons, six tests consistently statistically significantly different. classification changed 11/71 (15%) participants. 45% preferred virtual 33% in-person.Of 19 ACR-NB, we identified one or more problems with eight (42%) when moving administration. As use will likely increase, these issues need be addressed - potentially by validating a version Until then, caution must taken directly comparing test results. If future mixed approach, this should accounted during analysis.

Language: Английский

Citations

2

‘Food for Thought’—The Relationship between Diet and Cognition in Breast and Colorectal Cancer Survivors: A Feasibility Study DOI Open Access
Daniel G. Coro, Amanda D. Hutchinson, Kathryn A. Dyer

et al.

Nutrients, Journal Year: 2021, Volume and Issue: 14(1), P. 71 - 71

Published: Dec. 24, 2021

Survivors of cancer frequently experience persistent and troublesome cognitive changes. Little is known about the role diet nutrition plays in survivors' cognition. We explored feasibility collecting cross-sectional online data from Australian survivors breast colorectal to enable preliminary investigations relationships between cognition with fruit vegetable intake, Omega-3 Index (a biomarker long chain omega 3 fatty acid intake). A total 76 participants completed (and postal biomarker) collection (62 14 survivors): mean age 57.5 (±10.2) years, time since diagnosis 32.6 (±15.6) months. Almost all outcomes were met; however, technical difficulties reported for testing. In hierarchical linear regression models, none dietary variables interest significant predictors self-reported or objective Age, BMI, length treatment predicted some outcomes. demonstrated a viable online/postal method, reporting positive levels engagement satisfaction. Fruit, vegetable, omega-3 intake not this sample, however BMI functioning should be further investigated. Future research could adapt protocol longitudinally monitor assess impact on subsequent function, whether changes habits cancer.

Language: Английский

Citations

4

Reliable Online Auditory Cognitive Testing: An observational study (Preprint) DOI
Meher Lad, John‐Paul Taylor, Timothy D. Griffiths

et al.

Published: March 16, 2024

BACKGROUND Web-based experimentation, accelerated by the COVID-19 pandemic, has enabled large-scale participant recruitment and data collection. Auditory testing on web shown promise but faces challenges such as uncontrolled environments verifying headphone use. Prior studies have successfully replicated auditory experiments often involved younger participants, limiting generalizability to older adults with varying hearing abilities. This study explores feasibility of conducting reliable cognitive using a web-based platform, especially among adults. OBJECTIVE aims determine whether demographic factors age status influence participation in assess reproducibility measures—specifically speech-in-noise perception memory (AuM)—between in-person settings. Additionally, this examine relationship between musical sophistication, measured Goldsmiths Musical Sophistication Index (GMSI), measures across different environments. METHODS A total 153 participants aged 50 86 years were recruited from local registries clinics; 58 these returned for web-based, follow-up assessments. An additional 89 PREVENT cohort included study, forming combined sample. Participants completed tasks (Digits-in-Noise Speech-in-Babble), AuM tests frequency amplitude modulation rate, GMSI questionnaire. In-person was conducted soundproof room standardized equipment, while required use headphones quiet via app. The evaluated Pearson intraclass correlation coefficients, statistical analyses assessed relationships variables RESULTS Older those severe loss underrepresented follow-up. questionnaire demonstrated highest (<i>r</i>=0.82), showed moderate Speech-in-Babble <i>r</i>=0.55 <i>r</i>=0.75 rate <i>r</i>=0.44). There no significant differences settings (all <i>P</i>&gt;.05). previously reported associations scores, well sentence-in-noise perception, indicating consistency CONCLUSIONS is feasible yields results comparable testing, questionnaire-based like GMSI. While reproducibility, consistent replication key suggests that viable alternative cognition research. However, underrepresentation highlights need address barriers participation. Future work should explore methods enhance inclusivity, remote guided digital literacy equipment standards improve representativeness quality

Language: Английский

Citations

0