Exploring the Contrasts and Similarities of Dengue and SARS-CoV-2 Infections During the COVID-19 Era DOI Open Access
Alexis García, Juan Bautista De Sanctis

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(21), P. 11624 - 11624

Published: Oct. 29, 2024

Extensive research has been conducted on the SARS-CoV-2 virus in association with various infectious diseases to understand pathophysiology of infection and potential co-infections. In tropical countries, exposure local viruses may alter course coinfection. Notably, only a portion antibodies produced against proteins demonstrate neutralizing properties, immune response following natural tends be temporary. contrast, long-lasting IgG are common after dengue infections. cases where preexisting from an initial bind different serotype during subsequent infection, there is for antibody-dependent enhancement (ADE) formation complexes associated disease severity. Both infections can result immunodeficiency. Viral both interfere host's IFN-I signaling. Additionally, cytokine storm occur viral impairing proper response, autoantibodies wide array appear convalescence. Most reported typically short-lived. Vaccines affecting enhancing clearance. A comprehensive analysis pathogenicity revisited prevent severity, mortality.

Language: Английский

Diagnostic value of miR-193a-5p in severe pneumonia and its correlation with prognosis DOI Creative Commons

Xiaoji Su,

Lijuan Zhu, Jian Zhuo

et al.

Journal of Cardiothoracic Surgery, Journal Year: 2025, Volume and Issue: 20(1)

Published: Jan. 23, 2025

Language: Английский

Citations

0
miR-3188 inhibits hepatitis B virus transcription by targeting Bcl-2 DOI
Shijie Wang, Ying Xie,

F. Liu

et al.

Archives of Virology, Journal Year: 2024, Volume and Issue: 169(5)

Published: April 2, 2024

Language: Английский

Citations

3
The potential of circulating microRNAs as novel diagnostic biomarkers of COVID-19: a systematic review and meta-analysis DOI Creative Commons
Melaku Ashagrie Belete, Denekew Tenaw Anley, Sintayehu Simie Tsega

et al.

BMC Infectious Diseases, Journal Year: 2024, Volume and Issue: 24(1)

Published: Sept. 19, 2024

Language: Английский

Citations

2
Decoding the intricacies: a comprehensive analysis of microRNAs in the pathogenesis, diagnosis, prognosis and therapeutic strategies for COVID-19 DOI Creative Commons
Shukur Wasman Smail,

Sarah Mousa Hirmiz,

Akhter Ahmed Ahmed

et al.

Frontiers in Medicine, Journal Year: 2024, Volume and Issue: 11

Published: Oct. 7, 2024

The pandemic of coronavirus disease-19 (COVID-19), provoked by the appearance a novel named severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), required worldwide healthcare emergency. This has elicited an immediate need for accelerated research into its mechanisms disease, criteria diagnosis, methods forecasting outcomes, and treatment approaches. microRNAs (miRNAs), are diminutive RNA molecules, that non-coding participate in gene expression regulation post-transcriptionally, having important participation regulating immune processes. miRNAs have granted substantial interest their impact on viral replication, cell proliferation, modulation how host’s system responds. narrative review delves host miRNAs’ multifaceted roles within COVID-19 context, highlighting involvement disease progression, diagnostics, prognostics aspects, given stability biological fluids varied profiles when responding to infection. Additionally, we discuss complicated interactions between SARS-CoV-2 cellular machinery facilitated revealing dysregulation miRNA advances evasion, inflammatory responses. Furthermore, it investigates potential as therapeutic agents, whether synthetic or naturally occurring, which could be harnessed either mitigate harmful inflammation enhance antiviral However, searching more deeply is needed clarify involved pathogenesis COVID-19, diagnosis processes, prognostic assessments, approaches patients.

Language: Английский

Citations

1
Polypurine Reverse Hoogsteen hairpins as a therapeutic tool for SARS-CoV-2 infection DOI Creative Commons
Carlos J. Ciudad, Simonas Valiuska, José M. Rojas

et al.

Journal of Biological Chemistry, Journal Year: 2024, Volume and Issue: 300(11), P. 107884 - 107884

Published: Oct. 11, 2024

Language: Английский

Citations

0
Exploring the Contrasts and Similarities of Dengue and SARS-CoV-2 Infections During the COVID-19 Era DOI Open Access
Alexis García, Juan Bautista De Sanctis

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(21), P. 11624 - 11624

Published: Oct. 29, 2024

Extensive research has been conducted on the SARS-CoV-2 virus in association with various infectious diseases to understand pathophysiology of infection and potential co-infections. In tropical countries, exposure local viruses may alter course coinfection. Notably, only a portion antibodies produced against proteins demonstrate neutralizing properties, immune response following natural tends be temporary. contrast, long-lasting IgG are common after dengue infections. cases where preexisting from an initial bind different serotype during subsequent infection, there is for antibody-dependent enhancement (ADE) formation complexes associated disease severity. Both infections can result immunodeficiency. Viral both interfere host's IFN-I signaling. Additionally, cytokine storm occur viral impairing proper response, autoantibodies wide array appear convalescence. Most reported typically short-lived. Vaccines affecting enhancing clearance. A comprehensive analysis pathogenicity revisited prevent severity, mortality.

Language: Английский

Citations

0