Expert Review of Clinical Immunology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 10

Published: March 5, 2025

Atopic Dermatitis (AD) is a common chronic, recurrent inflammatory skin disease, characterized mainly by polymorphic lesions and severe itching, significantly affecting patients' physical mental health. The pathogenesis of AD complex, involving multiple factors such as genetics, environment, immunity, microbiota. In terms treatment, traditional systemic therapies are gradually being replaced more targeted molecular immunotherapies, the range topical medications has become diverse. However, research on treatment in special populations, children, pregnant women, lactating elderly, remains relatively limited. This review aims to discuss progress treatments for populations both domestically internationally, with focus personalized approaches. It covers many aspects hormones, antimicrobial drugs, small molecule nanotechnology microecological therapies, proposes each group problems that need be solved current research. Special have unique physiological characteristics, which may lead different responses medications. Therefore, strategies especially important this context. As insights into evolves, novel rise, holding promise

Language: Английский