Molecular mechanisms of action of DIM and its clinical application DOI
Е. А. Никитина, S. V. Orlova, Т. Т. Батышева

et al.

Medical alphabet, Journal Year: 2024, Volume and Issue: 19, P. 9 - 15

Published: Oct. 30, 2024

Optimal nutrition requires complete provision of the human needs not only for energy, macro- and micronutrients, but also minor biologically active substances. Some most promising chemoprotectors are glucosinolates their derivatives, such as 3,3’-diindolylmethane (DIM). DIM has ability to inhibit development progression neoplasia by regulating multiple intracellular signaling pathways. Currently, clinical efficacy is being studied in breast prostate cancer, possibility using DIM’s antioxidant anti-inflammatory properties neurodegenerative, metabolic immune diseases investigated.

Language: Английский

Nutrition in the prevention and treatment of skeletal muscle ageing and sarcopenia: a single nutrient, a whole food, and a whole diet approach DOI Open Access
Antoneta Granic, Avan Aihie Sayer, Rachel Cooper

et al.

Proceedings of The Nutrition Society, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 16

Published: Oct. 17, 2024

Loss of skeletal muscle strength and mass (sarcopenia) is common in older adults associated with an increased risk disability, frailty premature death. Finding cost-effective prevention treatment strategies for sarcopenia the growing ageing population therefore great public health interest. Although nutrition considered important factor aetiology sarcopenia, its potential and/or still being evaluated. Nutrition research utilises three main approaches to understand muscle-nutrition relationships, evaluating: single nutrients, whole foods diet effects - both alone or combined exercise. Applying these approaches, we summarise recent evidence from qualitative quantitative syntheses findings observational intervention studies healthy adults, those sarcopenia. We consider protein supplements, (fruits vegetables) Mediterranean as exemplars. There some beneficial supplementation ≥ 0·8 g/kg body weight/d on when exercise training sarcopenic adults. In contrast, function (strength physical performance) inconclusive. reasonably consistent epidemiological suggesting benefits higher fruits vegetables consumption better performance. Similarly, adherence studies. However, are lacking. This review discusses how current may inform development preventive optimal nutritional policy aimed at combatting

Language: Английский

Citations

5
Potatoes – a scoping review for Nordic Nutrition Recommendations 2023 DOI Creative Commons
Magdalena Rosell, Christine Delisle Nyström

Food & Nutrition Research, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 29, 2024

Potatoes comprise a common staple food in the Nordic and Baltic countries contribute to diet with vitamins, minerals, dietary fibre phytochemicals. However, potatoes may also be consumed processed forms added fat salt, which raises concerns about possible adverse health effects. The aim of this scoping review is describe overall evidence for role as basis setting updating food-based guidelines Nutrition Recommendations 2023. PubMed was searched systematic reviews meta-analyses, extracted on relevant outcomes. Current available indicates that moderate consumption not associated substantial risk chronic diseases, they part healthy diet. effects vary greatly depending cooking methods, studies indicate intake French fries/fried should limited. Overall, regarding very limited, associations need further investigated.

Language: Английский

Citations

4
Dietary intake among youth adhering to vegan, lacto-ovo-vegetarian, pescatarian or omnivorous diets in Sweden DOI Creative Commons

Isabelle Mulkerrins,

Anine Christine Medin, Synne Groufh-Jacobsen

et al.

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: March 10, 2025

Objective To assess the intakes of food groups, energy, and macronutrients among youth in Sweden who adhere to vegan, lacto-ovo-vegetarian, pescatarian or omnivorous diets. Further, evaluate youth’s adherence food-based dietary guidelines (FBDG). Design In this cross-sectional study, intake data was obtained through repeated non-consecutive 24-h recalls (24HDR) a screener assessing consumption frequency groups. Usual daily were estimated using Multiple Source Method (MSM), for usual groups 24HDR combined with frequency. Setting Gothenburg, Sweden, December 2022–January 2024. Participants total 235 (78% female, mean age 22 ± 2 years), consisting 60 vegans, 59 lacto-ovo-vegetarians, 55 pescatarians, 61 omnivores. Results For (median value), both g/d g/MJ, all plant-based had higher legumes meat analogs compared omnivores (for all, p < 0.001), vegans lacto-ovo-vegetarians dairy substitutes (vs. pescatarians omnivores, 0.001). Moreover, refined grain products = 0.012), nuts/seeds 0.002), vegetable oil 0.014). Omnivores fried/premade potato dishes lower plain potatoes Overall ‘sweets snack foods’ did not differ between energy (10 vs. 9 MJ/d, 0.016). Most macronutrient recommendations met across except carbohydrates (below omnivores), fiber pescatarians), saturated fatty acids (exceeded by vegans). FBDG whole grains, (23%) (2%) (3%), 0.001. No difference found FBDG’s fruits, berries, vegetables (10%), nuts (24%), (4%). Conclusion Swedish youth, regardless practice, need increase vegetables, nuts, limit discretionary foods better align nutrition recommendations.

Language: Английский

Citations

0
Current policies for promoting neglected and underutilized crop species in Burkina Faso and Niger DOI Creative Commons
Susanna Rokka, Hamid El Bilali, Teresa Borelli

et al.

International Journal of Agricultural Sustainability, Journal Year: 2025, Volume and Issue: 23(1)

Published: Feb. 13, 2025

Language: Английский

Citations

0
Extraction and Optimization of Lycopene From Selected Fruits and Their Assessment as an Ultraviolet Ray Protectant for Escherichia coli DOI Creative Commons
Anil Kumar,

Niharika Bhawsar,

Savita Manekar

et al.

Food Science & Nutrition, Journal Year: 2025, Volume and Issue: 13(4)

Published: April 1, 2025

Lycopene is known for protecting the skin from harmful UV rays, which why it widely used in cosmetics. In present investigation, fruits and vegetables like Capsicum annuum (C.a.), frutescens (C.f.), Carica papaya (C. p.), Citrullus lanatus l.), Solanum lycopersicum (S. l.) were extraction isolation of lycopene. The lycopene was isolated acetone to solubilize hydrophilic hydrophobic molecules hydrolyzed into 5% sodium sulfate a protic solvent mechanism. measurement content done by UV-Vis spectrophotometer at 503 nm (λ), absence peak range 440-530 extracted Furthermore, all Petri plates coated with film different concentrations on bottom surface lid plate. samples following ascending order lowest highest concentration: (C.a.) < (C.f.) p.) l.). pH value S. sample found be 6.2, maximum amount 3.36024 μg/mL, C. 4.5 minimum amount. 0.31824 μg/mL. R-square obtained increased adequate good quality; correlation variables between percentage remained same using equation y = 56.60×-250.5, their R 2 1 > 0.968, degraded, calculated. Escherichia coli colonies protected rays counted after intervals (24, 48, 72 h). effect measured 10, 20, 30 min exposure rays. Sample had UV-ray blocking potential, that is, 99.75%, percentage, 77.78%. Further research development will required determine its effectiveness, stability, practicality creating films as barrier against

Language: Английский

Citations

0
European Society for the Study of Obesity (EASO) Position Statement on medical nutrition therapy for the management of individuals with overweight or obesity and cancer DOI Creative Commons
Giovanna Muscogiuri, Luigi Barrea,

Silvia Bettini

et al.

Obesity Facts, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 20

Published: Oct. 21, 2024

Obesity, a prevalent and multifactorial disease, is linked to range of metabolic abnormalities, including insulin resistance, dyslipidemia, chronic inflammation. These imbalances not only contribute cardiometabolic diseases but also play significant role in cancer pathogenesis. The rising prevalence obesity underscores the need investigate dietary strategies for effective weight management individuals with overweight or cancer. This European Society Study Obesity (EASO) position statement aimed summarize current evidence on provide insights major nutritional interventions, Mediterranean diet (MedDiet), ketogenic (KD), intermittent fasting (IF), that should be adopted manage MedDiet, characterized by high consumption plant-based foods moderate intake olive oil, fish, nuts, has been associated reduced risk. KD IF are emerging interventions potential benefits loss health. KD, inducing ketosis, IF, through periodic cycles, may offer anticancer effects modifying tumor metabolism improving sensitivity. Despite promising results, these approaches limited inconsistent, challenges variability adherence personalized plans.

Language: Английский

Citations

2
Impact of Fruit Consumption on Gut Microbiota: Benefits, Contaminants, and Implications for Human Health DOI

Débora Fernandes Pinheiro,

Giselle Maria Maciel, Nayara Pereira Lima

et al.

Trends in Food Science & Technology, Journal Year: 2024, Volume and Issue: 154, P. 104785 - 104785

Published: Nov. 12, 2024

Language: Английский

Citations

2
Fruit juice – a scoping review for Nordic Nutrition Recommendations 2023 DOI Creative Commons
Magdalena Rosell, Christine Delisle Nyström

Food & Nutrition Research, Journal Year: 2024, Volume and Issue: 68

Published: Feb. 6, 2024

Fruit juice has a similar nutrient content as whole fruit and may in this respect be part of healthy diet. However, lower amount or lack fibre higher concentration sugars energy could also contribute to less satiation increase the risk excess intake. The aim scoping review is describe overall evidence for role basis setting updating food-based dietary guidelines Nordic Nutrition Recommendations 2023. PubMed was searched systematic reviews meta-analyses extracted on relevant health outcomes. Current available indicates that low moderate consumption not associated with an apparent chronic diseases have protective effects cardiovascular disease. association between intake weight gain remains unclear might concern some groups people. Overall, regarding limited.

Language: Английский

Citations

0
Noncausal effects of genetic predicted depression and gastric cancer risk: A NHANES and Mendelian randomization study DOI Creative Commons
Juanjuan Liu,

Yue hong Chen,

Pai qi Zhang

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: April 29, 2024

Abstract The relationship between gastric cancer and depression remains an area of active investigation, with recent studies suggesting a potential bidirectional association. We present analysis the correlation using data from National Health Nutrition Examination Survey (NHANES) Genome-Wide Association Studies (GWAS), employing Mendelian Randomization (MR) to explore causal links these conditions. NHANES adjusted for confounders such as lifestyle factors pre-existing health conditions, revealing higher incidence among individuals cancer. Stepwise regression models further established risk factor developing Conversely, MR genetic variants instrumental variables suggested that significantly impacts development depression, 24 single nucleotide polymorphisms (SNPs) showing significant association both Inverse Variance Weighted (IVW) method indicated effect on (OR: 0.979[0.962-0.995]), although strength varied different weighting methods. Reverse did not find impact occurrence cancer, 15 SNPs associated diseases but no observed 0.834 [0.504-1.380]). study's findings underscore importance considering mental well-being in treatment provide new direction future therapeutic approaches. However, limitations focus European ancestry lack specificity regarding types warrant research.

Language: Английский

Citations

0
Molecular mechanisms of action of DIM and its clinical application DOI
Е. А. Никитина, S. V. Orlova, Т. Т. Батышева

et al.

Medical alphabet, Journal Year: 2024, Volume and Issue: 19, P. 9 - 15

Published: Oct. 30, 2024

Optimal nutrition requires complete provision of the human needs not only for energy, macro- and micronutrients, but also minor biologically active substances. Some most promising chemoprotectors are glucosinolates their derivatives, such as 3,3’-diindolylmethane (DIM). DIM has ability to inhibit development progression neoplasia by regulating multiple intracellular signaling pathways. Currently, clinical efficacy is being studied in breast prostate cancer, possibility using DIM’s antioxidant anti-inflammatory properties neurodegenerative, metabolic immune diseases investigated.

Language: Английский

Citations

0