Vector competence of Culex quinquefasciatus from Santiago Island, Cape Verde, to West Nile Virus: exploring the potential effect of the vector native Wolbachia

Parasites & Vectors, Journal Year: 2024, Volume and Issue: 17(1)

Published: Dec. 23, 2024

Abstract Background Culex quinquefasciatus plays a crucial role as vector of West Nile virus (WNV). This mosquito species is widely distributed in Cape Verde, being found all inhabited islands the archipelago. However, no data are currently available on susceptibility local population to WNV. study aimed assess competence Cx. mosquitoes from Santiago Island, for WNV and explore potential impact its native Wolbachia transmission. Methods -infected uninfected female were exposed lineage 1 PT6.39 strain using Hemotek membrane feeding system. Mosquito samples, including body, legs, wings saliva, collected at days 7, 14 21 post-infection (dpi) infection through one-step quantitative real-time PCR (RT-qPCR). Results Verde exhibited high tested Also, treated females without their significantly higher load bodies greater dissemination rate 7 dpi than wild-type counterparts carrying . Conclusions The poses risk transmission this seems confer protection against early stages viral infection. Additional research required uncover mechanisms driving Graphical abstract

Language: Английский

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Analyses of Mosquito Species Composition, Blood-Feeding Habits and Infection with Insect-Specific Flaviviruses in Two Arid, Pastoralist-Dominated Counties in Kenya

Pathogens, Journal Year: 2023, Volume and Issue: 12(7), P. 967 - 967

Published: July 24, 2023

Insect-specific flaviviruses (ISFs), although not known to be pathogenic humans and animals, can modulate the transmission of arboviruses by mosquitoes. In this study, we screened 6665 host-seeking, gravid blood-fed mosquitoes for infection with assessed vertebrate hosts sampled in Baringo Kajiado counties; both dryland ecosystem counties Kenyan Rift Valley. Sequence fragments two ISFs were detected. Cuacua virus (CuCuV) was found three Mansonia (Ma.) africana. The genome sequenced next-generation sequencing (NGS), confirming 95.8% nucleotide sequence identity CuCuV detected sp. Mozambique. a potential novel ISF showing 72% Aedes flavivirus individual aegypti, Anopheles gambiae s.l., Ma. africana Culex (Cx.) univittatus, all having fed on human blood. Blood-meal analysis revealed that collected diverse hosts, primarily livestock, minor representation wild mammals, amphibians birds. impact arbovirus requires further research.

Language: Английский

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Risky business: human-related data is lacking from Lyme disease risk models

Frontiers in Public Health, Journal Year: 2023, Volume and Issue: 11

Published: Nov. 3, 2023

Used as a communicative tool for risk management, maps provide service to the public, conveying information that can raise awareness and encourage mitigation. Several studies have utilized determine risks associated with distribution of

Language: Английский

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Zoonosis virales emergentes de impacto global

Revista Arbitrada Interdisciplinaria de Ciencias de la Salud Salud y Vida, Journal Year: 2022, Volume and Issue: 6(1), P. 304 - 304

Published: March 1, 2022

Objetivo: Analizar las principales zoonosis virales emergentes y su impacto a nivel global en la presentación de epidemias pandemias que afectan salud humana. Método: Se desarrolló una revisión sistemática 15 artículos base datos PubMed. Análisis los resultados: Considerando que, inmensa mayoría casos, intervención o control fuente animal podría evitar problemas ulteriores pública, se hace necesario considerar desarrollar intervenciones integradas, tengan cuenta causas interactúan son responsables intersectoriales salud. Conclusión: El humano ecología el clima, junto con un transporte más rápido entre países regiones, han acelerado aparición reaparición patógenos zoonóticos.

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