Immersive virtual reality for improving cognitive deficits in children with ADHD: a systematic review and meta-analysis

Virtual Reality, Journal Year: 2023, Volume and Issue: 27(4), P. 3545 - 3564

Published: Feb. 18, 2023

Abstract Virtual reality (VR) shows great potential in treating and managing various mental health conditions. This includes using VR for training or rehabilitation purposes. For example, is being used to improve cognitive functioning (e.g. attention) among children with attention/deficit-hyperactivity disorder (ADHD). The aim of the current review meta-analysis evaluate effectiveness immersive VR-based interventions improving deficits ADHD, investigate moderators effect size assess treatment adherence safety. included seven randomised controlled trials (RCTs) ADHD comparing controls waiting list, medication, psychotherapy, training, neurofeedback hemoencephalographic biofeedback) on measures cognition. Results indicated large sizes favour outcomes global functioning, attention, memory. Neither intervention length nor participant age moderated functioning. Control group type (active vs passive control group), diagnostic status (formal vs. informal) novelty technology were not significant Treatment was similar across groups there no adverse effects. should be cautiously interpreted given poor quality studies small sample.

Language: Английский

---

Virtual Reality for the Rehabilitation of Acquired Cognitive Disorders: A Narrative Review

Bioengineering, Journal Year: 2023, Volume and Issue: 11(1), P. 35 - 35

Published: Dec. 28, 2023

This review article explores the use of Virtual Reality (VR) technology in cognitive rehabilitation for individuals with neurological conditions, such as stroke, traumatic brain injury, and neurodegenerative diseases. The introduction highlights challenges posed by impairments limitations traditional methods. VR is presented a transformative tool that immerses interactive environments, offering promising opportunities enhancing functions improving quality life. covers foundational principles VR, its applications across different clinical conditions domains, evaluates empirical evidence supporting efficacy. It also discusses advantages, limitations, challenges, ethical considerations rehabilitation. concludes exploring future developments, including advancements technology, integration Augmented (AR) artificial intelligence (AI), importance standardized assessment tools objective evaluation outcomes.

Language: Английский

---

Alzheimer’s Disease Treatment: The Search for a Breakthrough

Medicina, Journal Year: 2023, Volume and Issue: 59(6), P. 1084 - 1084

Published: June 4, 2023

As the search for modalities to cure Alzheimer's disease (AD) has made slow progress, research now turned innovative pathways involving neural and peripheral inflammation neuro-regeneration. Widely used AD treatments provide only symptomatic relief without changing course. The recently FDA-approved anti-amyloid drugs, aducanumab lecanemab, have demonstrated unclear real-world efficacy with a substantial side effect profile. Interest is growing in targeting early stages of before irreversible pathologic changes so that cognitive function neuronal viability can be preserved. Neuroinflammation fundamental feature involves complex relationships among cerebral immune cells pro-inflammatory cytokines, which could altered pharmacologically by therapy. Here, we an overview manipulations attempted pre-clinical experiments. These include inhibition microglial receptors, attenuation enhancement toxin-clearing autophagy. In addition, modulation microbiome-brain-gut axis, dietary changes, increased mental physical exercise are under evaluation as ways optimize brain health. scientific medical communities work together, new solutions may on horizon or halt progression.

Language: Английский

---

The influence of eight cognitive training regimes upon cognitive screening tool performance in post-stroke survivors: a network meta-analysis

Frontiers in Aging Neuroscience, Journal Year: 2024, Volume and Issue: 16

Published: July 19, 2024

Background Traditional meta-analysis offers only direct comparative evidence. The optimal cognitive training for poststroke impairment (PSCI) remains largely undetermined. Objectives This study aims to assess and compare the effectiveness of selected methods PSCI patients identify rank most effective intervention programs. Methods Searches were conducted in PubMed, Embase, Cochrane Library, Web science, China National Knowledge Infrastructure, Science Technology Journal Database, Wanfang Biomedical Database randomized controlled trials up September 30, 2023. Two researchers independently performed literature screening, data extraction, quality assessment. Network was utilized synthesize main findings. primary outcome focused on intervention’s impact subjective function, with secondary outcomes including effects activities daily living, motor functional independence. is registered PROSPERO (CRD42023463282). Results Fifty eligible identified, revealing eight distinct interventions. These interventions collectively demonstrate efficacy enhancing cognition. significantly improves overall living In Loewenstein Occupational Therapy Cognitive Assessment, Barthel Index, Fugl-Meyer Functional Independence Measure scales, a combination computer-based traditional outperformed conventional control group MD = 29.97 (95%CI: 16.3, 44.2), 18.67 9.78, 27.45), 28.76 5.46, 51.79) 42.2 5.25, 78.99). MMSE scale, virtual reality combined 8.01 3.6, 12.4). On MoCA exercise showed superior results 6.68 2.55, 10.78). Only training, as well alone, enhanced independence, no notable differences other pairwise Conclusion network suggests that augmenting modalities may enhance effectiveness. Specifically, incorporating appear surpass improving cognition, skills, findings this provide evidence-based guidance clinical decision-making. Systematic Review Registration https://www.crd.york.ac.uk/PROSPERO/ , identifier

Language: Английский

---

Virtual reality applications based on instrumental activities of daily living (iADLs) for cognitive intervention in older adults: a systematic review

Journal of NeuroEngineering and Rehabilitation, Journal Year: 2023, Volume and Issue: 20(1)

Published: Dec. 19, 2023

Abstract Background In recent years, the use of virtual reality (VR) as a complementary intervention in treating cognitive impairment has significantly increased. VR applications based on instrumental activities daily living (iADL-VR) could offer promising approach with greater ecological validity for groups impairments. However, effectiveness this is still debated. Objective This systematic review aims to synthesize effects iADL-VR interventions rehabilitate, train, or stimulate functions healthy adults and people mild (MCI) different types dementia. Methods A search was performed Scopus, PubMed, IEEE Xplore, Web Science, APA PsycNet databases until September 2022 repeated April 2023. The selected studies met terms, were peer-reviewed, included an intervention, written English. Descriptive, qualitative studies, reviews, assessment, non-intervention those unrelated iADL, focused motor aspects, non-degenerative disorders excluded. PEDro scale used assess methodological quality controlled studies. To present results, we organized extracted data into three tables, including scores, participant characteristics, study characteristics. Results Nineteen that inclusion exclusion criteria included. total sample reached 590 participants, mostly women (72.67%). Approximately 30% diagnosed Alzheimer’s disease dementia, 20% had impairment. Variables such authors year publication, design, type applied, duration main findings, conclusions extracted. Regarding demographic size, age, sex, years education, neurological diagnosis, dropouts, city country where took place recorded. Almost all showed improvements some outcomes after generally group than control group. Conclusion be beneficial improving performance older MCI component these tasks makes them very suitable transferring what been learned real world. transfer needs confirmed by further larger more homogeneous samples longer follow-up periods. no primary funding source registered PROSPERO under registration ID: 375166.

Language: Английский

---

Barriers to adopting therapeutic virtual reality: the perspective of clinical psychologists and psychotherapists

Frontiers in Psychiatry, Journal Year: 2025, Volume and Issue: 16

Published: March 18, 2025

Despite evidence supporting the effectiveness of Virtual Reality (VR) for mental disorders, VR adoption in therapy remains low. As VR-technology continues to advance, it is crucial examine individual and contextual barriers preventing implementation therapeutic VR. An online survey with closed open-ended questions regarding knowledge VR, VR-usage was conducted among clinical psychologists psychotherapists Austria (Mage=51.71 years, 76% women). Of 694 participants, only 10 reported using Chi-square tests revealed significant differences interest based on prior experience, employment status, professional training, cluster. Besides a small age effect, no effects gender or experience were found. Participants interested (interest group, IG) frequently cited other reasons (see thematic analysis) not having used yet. Those (no NIG) indicated lack relevance, perceived advantage, disinterest as Thematic analysis identified four themes shared by both IG NIG, each encompassing group-specific sub-themes: (lack knowledge, time, personal reasons), financial (costs, cost-benefit-ratio), (clinical applicability, concerns about "real" relationship), technological (immature technology, cybersickness, equipment). Significant are gaps constraints, motivation, all which highlight need training support enhance implementation.

Language: Английский

---

Neuropsychological and behavioral benefits of virtual cognitive rehabilitation training among pediatric population surviving malaria: A systematic review and meta-analysis

International Journal of Critical Illness and Injury Science, Journal Year: 2025, Volume and Issue: 15(1), P. 35 - 43

Published: Jan. 1, 2025

Severe and nonsevere forms of repeated malaria can cause numerous cognitive impairments, usually in the aspects problem-solving, executive function, memory, attention. Several studies have suggested that rehabilitation treatment interventions be effective treating symptoms cerebral (CM). Virtual reality (VR) technology potentiates as a useful tool for assessment processes. The aim present systematic review is to examine neuropsychological behavioral benefits virtual training among children with Malaria. Cumulative Index Nursing Allied Health Literature, Physiotherapy Evidence Database (PEDro), Excerpta Medica Database, Medical Literature Analysis Retrieval System Online, PubMed, Web Science, Google Scholar, ClinicalTrials.gov., Global databases were searched investigated effect VR on functions post-CM. methodological quality was evaluated using PEDro scale. Six included qualitative analyses, five being randomized controlled trials one parallel-group trial. scores scale ranged from 5 7 mean score 6. results showed improvement various such as: attention CM survivors. Using computerized protocol 16–24 sessions, each 45–60 min duration, 2–3 sessions per week, may improve performance behavior terms functions, working severe

Language: Английский

---

Effects of virtual reality-based interventions on cognitive function, emotional state, and quality of life in patients with mild cognitive impairment: a meta-analysis

Frontiers in Neurology, Journal Year: 2025, Volume and Issue: 16

Published: April 2, 2025

This meta-analysis aims to systematically evaluate the effects of virtual reality (VR)-based interventions on cognitive function, emotional state, and quality life in patients with mild impairment (MCI). A comprehensive literature search was conducted using five databases from their inception June 2024. The inclusion criteria focused randomized controlled trials (RCTs) that examined VR-based adults aged 60 or older diagnosed MCI. primary outcome while secondary outcomes included life, dynamic balance. To investigate potential sources heterogeneity, subgroup analyses meta-regression were conducted. Subgroup stratified by VR parameters (immersion level, duration, session, frequency) demographic factors (geographic region, education male proportion). Publication bias assessed funnel plots Egger's regression test. "trim fill" method employed adjust for any detected publication bias. certainty evidence evaluated Grading Recommendations Assessment, Development, Evaluation (GRADE) framework GRADEpro GDT software. total 30 RCTs involving 1,365 participants 9 countries across 4 continents included. revealed significantly improved global cognition, as Montreal Cognitive Assessment (MoCA; SMD = 0.82, 95% CI: 0.27 1.38, p 0.003, GRADE: moderate) Mini-Mental State Examination (MMSE; 0.83, 0.40 1.26, 0.0001, low). Additionally, enhanced attention, measured Digit Span Backward (DSB; 0.61, 0.21 1.02, low) Forward (DSF; 0.89, 0.34 1.45, 0.002, Improvements also observed indicated scores Instrumental Activities Daily Living (IADL; 0.22, 0.00 0.45, 0.049, moderate). However, no significant found executive memory, verbal fluency, visual abilities, status, balance (p > 0.05). analysis more effective when semi-immersive VR, session durations ≤60 min a frequency than twice per week. Participants Asia Europe demonstrated better outcomes, lower proportion (≤ 40%) associated improvements targeted domains. findings indicate can improve individuals further optimal min, intervention frequencies exceeding week, studies Europe, participant groups ≤40%. Moreover, study provides valuable insights into suggesting may positively impact state appropriately tailored such immersion frequency, other relevant parameters.

Language: Английский

---

Next generation technologies for diagnosis

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 265 - 288

Published: Jan. 1, 2025

Language: Английский

---

Effects of virtual reality technology on attention deficit in children with ADHD: A systematic review and Meta-analysis

Journal of Affective Disorders, Journal Year: 2025, Volume and Issue: 384, P. 127 - 134

Published: May 8, 2025

Language: Английский

---