Cardiac Baroreflex Is Preserved After the Recovery From COVID‐19 Men and Women

Journal of Clinical Hypertension, Journal Year: 2025, Volume and Issue: 27(2)

Published: Feb. 1, 2025

ABSTRACT We sought to investigate whether mild COVID‐19 impairs cardiac baroreflex sensitivity (cBRS), using the modified Oxford protocol, in young healthy men and women 12–14 weeks after recovering from infection. Participants were distributed into two groups: Non‐COVID‐19 group (NCG: n = 6 [30 ± 3years; 26 1 kg/m 2 ] 5 [25 years; 25 ]) recovered (RCG: [29 3 10 [32 4 22 ]), RCG tested positive (RT‐PCR) 12 14 before protocol. Beat‐to‐beat finger blood pressure (BP) heart rate (HR) measured during a bolus of sodium nitroprusside (SNP) phenylephrine (PHE), control condition cold pressor test (CPT) moderate dynamic handgrip exercise (GRIP). Resting systolic BP was higher (135 mmHg vs. 122 mmHg, p 0.01). Both CPT GRIP maneuvers increased HR BP; SNP diminished evoked reflex‐mediated increase HR; PHE BP, resulting decrease HR. Of note, cBRS for or did not differ between groups under studied conditions: (SNP, 0.39; PHE, 0.50); 0.09; PHE: 0.82); 0.35; 0.53). In conclusion, seem impair

Language: Английский

Investigating autonomic nervous system dysfunction among patients with post-COVID condition and prolonged cardiovascular symptoms

Frontiers in Medicine, Journal Year: 2023, Volume and Issue: 10

Published: Oct. 9, 2023

Heart Rate Variability (HRV) and arterial pressure (AP) variability their responses to head-up tilt test (HUTT) were investigated in Post-COVID-19 syndrome (PCS) patients reporting tachycardia and/or postural hypotension. Besides tachycardia, PCS also showed attenuation of the following HRV parameters: RMSSD [square root mean sum squares differences between adjacent normal-to-normal (NN) intervals] from statistical measures; power RR (beat-to-beat interval) spectra at HF (high frequency) linear method spectral analysis; occurrence 2UV (two unlike variation) pattern nonlinear symbolic new family statistics named sample entropy, when compared control subjects. Basal AP LF (low systolic similar subjects, while 0 V (zero patterns analysis exacerbated patients. Despite a decrease RMSSD, no parameter changed during HUTT reassessed after 6 months higher percentage RR. Moreover, lower AP, elicited HR (heart rate) identical The suggest an autonomic dysfunction with sympathetic predominance In contrast, lack indices indicates marked impairment control. Of note, reassessment that noxious effect COVID-19 on tended fade over time.

Language: Английский