Frontiers in Microbiology,
Journal Year:
2024,
Volume and Issue:
15
Published: June 24, 2024
Oral
health
is
critical
for
total
body
and
well-being;
however,
little
improvement
in
oral
status
has
occurred
the
U.S.
over
past
20
years.
Tooth
decay
gum
disease
remain
highly
prevalent,
with
more
than
90%
50%
of
adults
suffering
from
these
conditions,
respectively.
To
combat
this
lack
improvement,
alternative
approaches
to
dental
care
are
now
being
suggested.
One
such
therapy
probiotics
care.
In
cavity,
probiotic
strains
have
been
shown
reduce
levels
pathogens,
inhibit
formation
caries,
bacteria
that
cause
halitosis.
However,
as
market
expands,
many
products
contain
bacterial
species
no
documented
benefits
leading
confusion
mistrust
among
consumers
clinicians.
This
enhanced
by
regulatory
which
puts
onus
safety
efficacy
on
manufacturer
rather
a
central
body.
The
overarching
goal
review
provide
clinicians
evidence
supporting
(or
refuting)
marketed
sale
United
States.
includes
defining
what
constitutes
an
product
strain
level
analysis
candidate
genera
Streptococcus,
Lactobacillus,
Bifidobacterium,
Bacillus.
Additionally,
prebiotics
postbiotics
will
be
discussed.
Finally,
set
considerations
provided
empower
decision
making.
Together,
improve
understanding
US
professionals
consumers.
Frontiers in Veterinary Science,
Journal Year:
2023,
Volume and Issue:
9
Published: Jan. 4, 2023
Many
benefits
have
been
found
in
supplementing
tannins
or
soybean
isoflavones
to
poultry,
including
increased
body
weight
gain,
antioxidant
activity,
and
better
intestinal
morphology.
However,
few
studies
tested
the
influence
of
dandelion
supplementation
on
Wenchang
chickens.
This
study
investigates
effects
dietary
with
growth
performance,
function,
health
female
A
total
300
chickens
were
randomly
divided
into
five
groups,
six
replicates
per
group
10
broilers
replicate.
The
control
(Con)
fed
a
basal
diet;
four
experimental
groups
diet
different
supplements:
mg/kg
tannin
(DT1),
500
(DT2),
isoflavone
(SI1),
(SI2).
experiment
lasted
40
days.
results
showed
that
final
(BW)
average
daily
gain
(ADG)
higher
DT2
SI1
than
Con
(P
<
0.05).
In
addition,
level
serum
albumin
<0.05);
concentrations
aspartate
aminotransferase
glucose
significantly
0.05)
concentration
triglycerides
DT1
catalase
(CAT)
was
ileum
pH
value
lower
jejunum
villus
height
mucosal
muscularis
thickness
0.05),
whereas
crypt
depth
decreased
compared
messenger
RNA
(mRNA)
expression
zonula
occludens
1
(ZO-1)
duodenum
those
occludin,
ZO-1,
claudin-1
upregulated
group.
Moreover,
exhibited
reduced
microbiota
diversity
relative
group,
as
evidenced
by
Simpson
Shannon
indexes.
Compared
abundance
Proteobacteria
Barnesiella
Overall,
improved
biochemical
indexes,
morphology
modulated
cecal
composition
Microbiome Research Reports,
Journal Year:
2024,
Volume and Issue:
3(2)
Published: Feb. 22, 2024
Background:
The
gut
and
its
microbiome
have
a
major
impact
on
many
aspects
of
health
are
therefore
also
an
attractive
target
for
drug-
or
food-based
therapies.
Here,
we
report
the
added
value
combining
screening
model,
i-screen,
with
fresh
intestinal
tissue
explants
in
microfluidic
gut-on-a-chip
Intestinal
Explant
Barrier
Chip
(IEBC).
Methods:
Adult
human
(fecal
pool
6
healthy
donors)
was
cultured
anaerobically
i-screen
platform
24
h,
without
exposure
to
4
mg/mL
inulin.
cell-free
culture
supernatant
subsequently
applied
luminal
side
adult
colon
(n
=
3
donors),
fixed
IEBC,
h
effects
were
evaluated.
Results:
supplementation
media
inulin
promoted
growth
Anaerostipes
,
Bifidobacterium
Blautia
Collinsella
vitro
triggered
elevated
production
butyrate
by
microbiota.
Human
exposed
inulin-treated
control
short-chain
fatty
acids
(SCFAs)
showed
improved
barrier
integrity
measured
28.2%-34.2%
reduction
FITC-dextran
4000
(FD4)
leakage
1.3
times
lower
transport
antipyrine.
Furthermore,
release
pro-inflammatory
cytokines
IL-1β,
IL-6,
IL-8,
TNF-α
reduced
under
these
circumstances.
Gene
expression
profiles
confirmed
findings,
but
more
profound
compared
SCFA-supplemented
supernatant.
Conclusion:
combination
IEBC
facilitates
study
complex
processes
such
as
host-microbial
metabolite
interaction
health.
Frontiers in Microbiology,
Journal Year:
2024,
Volume and Issue:
15
Published: June 24, 2024
Oral
health
is
critical
for
total
body
and
well-being;
however,
little
improvement
in
oral
status
has
occurred
the
U.S.
over
past
20
years.
Tooth
decay
gum
disease
remain
highly
prevalent,
with
more
than
90%
50%
of
adults
suffering
from
these
conditions,
respectively.
To
combat
this
lack
improvement,
alternative
approaches
to
dental
care
are
now
being
suggested.
One
such
therapy
probiotics
care.
In
cavity,
probiotic
strains
have
been
shown
reduce
levels
pathogens,
inhibit
formation
caries,
bacteria
that
cause
halitosis.
However,
as
market
expands,
many
products
contain
bacterial
species
no
documented
benefits
leading
confusion
mistrust
among
consumers
clinicians.
This
enhanced
by
regulatory
which
puts
onus
safety
efficacy
on
manufacturer
rather
a
central
body.
The
overarching
goal
review
provide
clinicians
evidence
supporting
(or
refuting)
marketed
sale
United
States.
includes
defining
what
constitutes
an
product
strain
level
analysis
candidate
genera
Streptococcus,
Lactobacillus,
Bifidobacterium,
Bacillus.
Additionally,
prebiotics
postbiotics
will
be
discussed.
Finally,
set
considerations
provided
empower
decision
making.
Together,
improve
understanding
US
professionals
consumers.
