Advances in Polymer Technology,
Journal Year:
2023,
Volume and Issue:
2023, P. 1 - 12
Published: March 11, 2023
In
this
study,
both
polyvinyl
chloride
(PVC)
and
polyacrylonitrile
(PAN)
were
dissolved
in
dimethyl
formaldehyde
(DMF)
with
8
wt.
%
concentrations
at
25
:
75,
50
50,
75
of
PVC:
PAN
blending.
For
the
investigation
homogeneity
compatibility
mixture
polymer
solutions,
it
is
examined
by
rheological
properties
such
as
viscosity,
shear
stress,
rate,
calculation
flow
behavior
index,
while
stability
high
density
nanofibers
without
beads
used
field-emission
scanning
electron
microscopy
(FE-SEM),
Fourier
transform
near-infrared
spectroscopy
(FT-NIR),
X-ray
diffraction
(XRD),
differential
calorimetry-thermogravimetric
analysis
(DSC-TGA).
The
results
show
that
blending
PVC
leads
to
improving
electro
spun
ability
more
stability,
mean
nanofiber
diameter
was
PAN.
Moreover,
mechanical
are
ultimate
tensile
strength
modulus
elasticity
decreasing
ration
from
pure
71%
83%,
respectively,
elongation
break
increases
79%,
decomposition
temperatures
decreased
451.96
345.38°C
when
changing
content
On
other
hand,
hydrophobicity
hydrophilic
increased
blends.
Furthermore,
low
interaction
between
chains
polymers
crystallinity
(%)
crystalline
size
(nm)
blend
slightly
compared
polymers.
According
all
tests,
25:
best
ratio,
which
gave
a
stable
produced
compatible
Molecules,
Journal Year:
2023,
Volume and Issue:
28(6), P. 2501 - 2501
Published: March 9, 2023
The
goal
of
the
current
work
was
to
create
an
antibacterial
agent
by
using
polycaprolactone/chitosan
(PCL/CH)
nanofibers
loaded
with
Cordia
myxa
fruit
extract
(CMFE)
as
antimicrobial
for
wound
dressing.
Several
characteristics,
including
morphological,
physicomechanical,
and
mechanical
surface
wettability,
activity,
cell
viability,
in
vitro
drug
release,
were
investigated.
inclusion
CMFE
PCL/CH
led
increased
swelling
capability
maximum
weight
loss.
SEM
images
PCL/CH/CMFE
mat
showed
a
uniform
topology
free
beads
average
fiber
diameter
195.378
nm.
Excellent
activity
shown
towards
Escherichia
coli
(31.34
±
0.42
mm),
Salmonella
enterica
(30.27
0.57
Staphylococcus
aureus
(21.31
0.17
Bacillus
subtilis
(27.53
1.53
Pseudomonas
aeruginosa
(22.17
0.12
mm)
based
on
inhibition
zone
assay.
sample
containing
5
wt%
had
lower
water
contact
angle
(47
3.7°),
high
porosity,
compared
neat
mat.
release
5%
CMFE-loaded
proven
be
anomalous
non-Fickian
diffusion
Korsmeyer-Peppas
model.
Compared
pure
PCL
membrane,
PCL-CH/CMFE
membrane
exhibited
suitable
cytocompatibility
L929
cells.
In
conclusion,
fabricated
nanofibrous
films
demonstrated
bioavailability,
properties
that
can
used
dressings.
Materials,
Journal Year:
2023,
Volume and Issue:
16(18), P. 6076 - 6076
Published: Sept. 5, 2023
This
comprehensive
review
illuminates
the
various
methods
of
chitosan
extraction,
its
antibacterial
properties,
and
multifarious
applications
in
diverse
sectors.
We
delve
into
chemical,
physical,
biological,
hybrid,
green
extraction
techniques,
each
which
presents
unique
advantages
disadvantages.
The
choice
method
is
dictated
by
multiple
variables,
including
desired
properties
chitosan,
resource
availability,
cost,
environmental
footprint.
explore
intricate
relationship
between
chitosan’s
activity
such
as
cationic
density,
molecular
weight,
water
solubility,
pH.
Furthermore,
we
spotlight
burgeoning
chitosan-based
materials
like
films,
nanoparticles,
nonwoven
materials,
hydrogels
across
food,
biomedical,
agricultural
concludes
highlighting
promising
future
underpinned
technological
advancements
growing
sustainability
consciousness.
However,
critical
challenges
optimizing
production
for
efficiency
remain
to
be
tackled.
RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(29), P. 20992 - 21034
Published: Jan. 1, 2024
This
paper
presents
a
comprehensive
review
of
recent
advancements
in
utilizing
zinc
oxide
nanoparticles
(ZnO
NPs)
to
enhance
antimicrobial
and
UV
protective
properties
healthcare
solutions.
Small,
Journal Year:
2024,
Volume and Issue:
20(24)
Published: Jan. 4, 2024
Abstract
Attempts
are
made
to
design
a
system
for
sustaining
the
delivery
of
copper
ions
into
diabetic
wounds
and
induce
angiogenesis
with
minimal
dose‐dependent
cytotoxicity.
Here,
dual
drug‐delivery
micro/nanofibrous
core‐shell
is
engineered
using
polycaprolactone/sodium
sulfated
alginate‐polyvinyl
alcohol
(PCL/SSA‐PVA),
as
core/shell
parts,
by
emulsion
electrospinning
technique
optimize
sustained
oxide
nanoparticles
(CuO
NP).
Herein,
different
concentrations
CuO
NP
(0.2,
0.4,
0.8,
1.6%w/w)
loaded
core
part
system.
The
morphological,
biomechanical,
biocompatibility
properties
scaffolds
fully
determined
in
vitro
vivo.
0.8%w/w
scaffold
reveals
highest
level
tube
formation
HUVEC
cells
also
upregulates
pro‐angiogenesis
genes
(VEGFA
bFGF)
expression
no
cytotoxicity
effects.
presence
SSA
its
interaction
NP,
structure
sustain
release
provide
non‐toxic
microenvironment
cell
adhesion
formation,
sign
adverse
immune
response
optimized
significantly
accelerates
wound
healing
rat
model.
This
study
strongly
suggests
NP‐loaded
PCL/SSA‐PVA
an
excellent
dressing
improved
healing.
Polymers,
Journal Year:
2023,
Volume and Issue:
15(5), P. 1079 - 1079
Published: Feb. 21, 2023
The
development
of
scaffolding
obtained
by
electrospinning
is
widely
used
in
tissue
engineering
due
to
porous
and
fibrous
structures
that
can
mimic
the
extracellular
matrix.
In
this
study,
poly
(lactic-co-glycolic
acid)
(PLGA)/collagen
fibers
were
fabricated
method
then
evaluated
cell
adhesion
viability
human
cervical
carcinoma
HeLa
NIH-3T3
fibroblast
for
potential
application
regeneration.
Additionally,
collagen
release
was
assessed
fibroblasts.
fibrillar
morphology
PLGA/collagen
verified
scanning
electron
microscopy.
fiber
diameter
decreased
(PLGA/collagen)
up
0.6
µm.
FT-IR
spectroscopy
thermal
analysis
confirmed
both
process
blend
with
PLGA
give
structural
stability
collagen.
Incorporating
matrix
promotes
an
increase
material's
rigidity,
showing
elastic
modulus
(38%)
tensile
strength
(70%)
compared
pure
PLGA.
found
provide
a
suitable
environment
growth
lines
as
well
stimulate
release.
We
conclude
these
scaffolds
could
be
very
effective
biocompatible
materials
regeneration,
suggesting
their
applications
bioengineering.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2023,
Volume and Issue:
11
Published: Jan. 19, 2023
The
poor
solubility
of
numerous
drugs
pose
a
long-existing
challenge
to
the
researchers
in
fields
pharmaceutics,
bioengineering
and
biotechnology.
Many
"top-down"
"bottom-up"
nano
fabrication
methods
have
been
exploited
provide
solutions
for
this
issue.
In
study,
combination
strategy
top-down
process
(electrospinning)
bottom-up
(self-emulsifying)
was
demonstrated
be
useful
enhancing
dissolution
typical
poorly
water-soluble
anticancer
model
drug
(paclitaxel,
PTX).
With
polyvinylpyrrolidone
(PVP
K90)
as
filament-forming
matrix
carrier,
polyoxyethylene
castor
oil
(PCO)
emulsifier,
triglyceride
(TG)
phase,
Both
single-fluid
blending
coaxial
were
utilized
prepare
medicated
nanofibers.
Scanning
electron
microscope
transmission
(TEM)
results
clearly
morphology
inner
structures
lipid
nanoparticles
emulsions
after
self-emulsification
also
assessed
through
TEM.
encapsulation
efficiency
(EE)
vitro
tests
that
cores-shell
nanofibers
could
better
self-emulsifying
int
terms
higher
EE
sustained
release
profile.
Meanwhile,
an
increase
sheath
fluid
rate
benefit
even
results,
suggesting
clear
process-property-performance
relationship.
protocols
reported
here
pave
anew
way
effective
oral
delivery
drug.
