Materials Today Chemistry, Journal Year: 2025, Volume and Issue: 44, P. 102557 - 102557
Published: Feb. 8, 2025
Language: Английский
Journal of Orthopaedic Translation, Journal Year: 2023, Volume and Issue: 42, P. 94 - 112
Published: Sept. 1, 2023
Currently, metal implants are widely used in orthopedic surgeries, including fracture fixation, spinal fusion, joint replacement, and bone tumor defect repair. However, conventional difficult to be customized according the recipient's skeletal anatomy characteristics, leading difficulties meeting individual needs of patients. Additive manufacturing (AM) or three-dimensional (3D) printing technology, an advanced digital fabrication technique capable producing components with complex precise structures, offers opportunities for personalization. We systematically reviewed literature on 3D over past 10 years. Relevant animal, cellular, clinical studies were searched PubMed Web Science. In this paper, we introduce method characteristics biometals summarize properties their applications surgery. On basis, discuss potential possibilities further generalization improvement. technology has facilitated use different procedures. By combining medical images from techniques such as CT MRI, allows based injured tissue. Such patient-specific not only reduce excessive mechanical strength eliminate stress-shielding effects, but also improve biocompatibility functionality, increase cell nutrient permeability, promote angiogenesis growth. addition, advantages low cost, fast cycles, high reproducibility, which can shorten patients' surgery hospitalization time. Many trials have been conducted using implants. modeling software, operation equipment, demand implant materials, lack guidance relevant laws regulations limited its application. There personalization, promotion osseointegration, short production cycle, material utilization. With continuous learning software by surgeons, improvement development materials that better meet needs, regulations, applied more surgeries. Precision, intelligence, personalization future direction orthopedics. It is reasonable believe will deeply integrated artificial 4D printing, big data play a greater role eventually become important part economy. aim latest developments engineers surgeons design closely mimic morphology function native bone.
Language: Английский
Citations
95
Materials Today Bio, Journal Year: 2023, Volume and Issue: 20, P. 100636 - 100636
Published: April 15, 2023
Strontium (Sr) and strontium ranelate (SR) are commonly used therapeutic drugs for patients suffering from osteoporosis. Researches have showed that Sr can significantly improve the biological activity physicochemical properties of materials
Language: Английский
Citations
44
Journal of Alloys and Compounds, Journal Year: 2024, Volume and Issue: 989, P. 174418 - 174418
Published: April 6, 2024
Language: Английский
Citations
34
Surfaces and Interfaces, Journal Year: 2025, Volume and Issue: unknown, P. 105735 - 105735
Published: Jan. 1, 2025
Language: Английский
Citations
2
Frontiers in Bioengineering and Biotechnology, Journal Year: 2025, Volume and Issue: 13
Published: Feb. 26, 2025
Porous titanium implants are becoming an important tool in orthopedic clinical applications. This review provides a comprehensive survey of recent advances porous for use. First, the briefly describes characteristics bone and design requirements implants. Subsequently, pore size structural alloy materials presented, then we introduce application practice, including spine surgery, joint treatment tumors. Following that, describe surface modifications applied to obtain better biological functions. Finally, discuss incorporating environmental responsive mechanisms into achieve additional functionalities.
Language: Английский
Citations
2
Colloids and Surfaces B Biointerfaces, Journal Year: 2023, Volume and Issue: 224, P. 113188 - 113188
Published: Feb. 1, 2023
Language: Английский
Citations
42
Journal of Materials Research and Technology, Journal Year: 2024, Volume and Issue: 30, P. 3780 - 3806
Published: April 16, 2024
Solid titanium alloys are extensively employed in orthopedic applications due to their reliable mechanical strength, but the stress shielding phenomenon caused by its high elastic modulus and disadvantage of lack bone integration may lead clinical complications. The design porous structure is a feasible approach reduce promote vascular ingrowth. This paper reviewed application current challenges solid implants orthopedics. To address drawbacks explore that can effectively integrate with tissue while possessing sufficient this review discussed latest preclinical research from perspectives structural design, surface modification, material composition. parameters affect ingrowth strength implants, including porosity, pore size, cellular structure, gradient were presented. Based on progress, various modification techniques aimed at enhancing performance overviewed. Moreover, range nickel-titanium alloy, β-titanium high-entropy composite investigated for prospective Overall, provided valuable insights into state highlighted potential improving outcomes
Language: Английский
Citations
10
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 274, P. 133153 - 133153
Published: June 17, 2024
Language: Английский
Citations
10
Materials Research Bulletin, Journal Year: 2025, Volume and Issue: unknown, P. 113407 - 113407
Published: Feb. 1, 2025
Language: Английский
Citations
1
Heliyon, Journal Year: 2023, Volume and Issue: 10(1), P. e23779 - e23779
Published: Dec. 18, 2023
Language: Английский
Citations
22