Frontiers of Optoelectronics,
Journal Year:
2024,
Volume and Issue:
17(1)
Published: Dec. 9, 2024
Abstract
Achilles
tendon
injuries,
as
a
widely
existing
disease,
have
attracted
lot
of
research
interest.
Mueller
matrix
polarimetry,
novel
label-free
quantitative
imaging
method,
has
been
used
in
various
applications
lesion
identification
and
pathological
diagnosis.
However,
focusing
on
the
recovery
process
current
optical
methods
not
yet
achieved
precise
evaluation.
In
this
study,
using
injury
samples
were
characterized
specifically,
efficacy
different
schemes
was
evaluated
accordingly.
Experiments
indicate
that
injured
tendons
show
less
phase
retardance,
larger
diattenuation,
relatively
disordered
orientation.
The
combination
experiments
with
Monte
Carlo
simulation
results
illustrate
microscopic
mechanism
from
three
aspects,
is,
increased
fiber
diameter,
more
consistent
orientation,
greater
birefringence
induced
by
collagen
protein.
Finally,
based
statistical
distribution
polarization
measurements,
specific
characterization
parameter
extracted
to
construct
image,
which
cannot
only
intuitively
samples,
but
also
give
evaluation
treatment.
Graphical
Annals of Medicine,
Journal Year:
2024,
Volume and Issue:
56(1)
Published: May 13, 2024
Tendons
are
fibroblastic
structures
that
link
muscle
and
bone.
There
two
kinds
of
tendon
injuries,
including
acute
chronic.
Each
form
injury
or
deterioration
can
result
in
significant
pain
loss
function.
The
recovery
damage
is
a
complex
time-consuming
process.
Depending
on
the
anatomical
location
tissue,
clinical
outcomes
not
same.
healing
wound
process
divided
into
three
stages
overlap:
inflammation,
proliferation,
tissue
remodeling.
Furthermore,
curing
has
high
re-tear
rate.
Faced
with
challenges,
management
still
issue
must
be
resolved
as
soon
possible.
Several
newer
directions
breakthroughs
have
emerged
recent
years.
This
article
describes
summarizes
advances
recovery,
along
stem
cell
therapy,
gene
Platelet-rich
plasma
remedy,
growth
factors,
drug
treatment,
engineering.
Despite
fast-growing
research
still,
none
them
translated
to
setting.
review
provides
detailed
overview
injuries
potential
preclinical
approaches
for
treating
injuries.
Veterinary Sciences,
Journal Year:
2024,
Volume and Issue:
11(5), P. 190 - 190
Published: April 26, 2024
Musculoskeletal
injuries
such
as
equine
osteoarthritis,
osteoarticular
defects,
tendonitis/desmitis,
and
muscular
disorders
are
prevalent
among
sport
horses,
with
a
fair
prognosis
for
returning
to
exercise
or
previous
performance
levels.
The
field
of
medicine
has
witnessed
rapid
fruitful
development,
resulting
in
diverse
range
therapeutic
options
musculoskeletal
problems.
Staying
abreast
these
advancements
can
be
challenging,
prompting
the
need
comprehensive
review
commonly
used
recent
treatments.
aim
is
compile
current
managing
injuries,
spanning
from
simple
complex
physiotherapy
techniques,
conservative
treatments
including
steroidal
non-steroidal
anti-inflammatory
drugs,
hyaluronic
acid,
polysulfated
glycosaminoglycans,
pentosan
polysulfate,
polyacrylamides,
promising
regenerative
therapies
hemoderivatives
stem
cell-based
therapies.
Each
modality
scrutinized
its
benefits,
limitations,
potential
synergistic
actions
facilitate
their
most
effective
application
intended
healing/regeneration
injured
tissue/organ
subsequent
patient
recovery.
While
have
emerged
particularly
multidisciplinary
approach
underscored
throughout
discussion,
emphasizing
importance
considering
various
modalities
tandem.
International Journal of Polymeric Materials,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 26
Published: May 2, 2024
Nanotechnological
advancements
has
facilitated
tissue
engineering
(TE)
in
functioning
as
advanced
biological
alternatives
for
use
repairing
or
replacing
damaged
human
tissues
organs.
Synthetic
biopolymeric
bionanoarchitectures
garnered
wide
attention
usage
construction
of
TE
scaffolds
attributed
to
their
inherent
biocompatibility
and
biodegradation
features.
For
effective
three
dimensional
(3D)
TE,
commonly
utilized
synthetic
matrices
includes
saturated
poly
(α-hydroxy
esters),
such
(α-caprolactone)
(PCL),
(lactic
acid)
(PLA),
(glycolic
(PGA),
acid-co-glycolic
(PLGA),
so
on.
In
a
bid
improve
mechanically,
cellularly
adherence
well
proliferation
features,
nanoparticulates/nanomaterials
(NMs)
including
carbon
derivatives,
nanoclay
apatite
metallic
nanoparticulates
on,
have
been
extensively
incorporated
within
these
matrices.
Hence,
this
paper
presents
emerging
advances
construction,
deciphering
features
PLA
hybrid
applications.
Materials Today Bio,
Journal Year:
2024,
Volume and Issue:
29, P. 101342 - 101342
Published: Nov. 14, 2024
Hydrogels,
that
are
crosslinked
polymer
networks,
can
absorb
huge
quantities
of
water
and/or
biological
fluids.
Their
physical
properties,
such
as
elasticity
and
soft
tissue,
together
with
their
biocompatibility
biodegradability,
closely
resemble
living
tissues.
The
versatility
hydrogels
has
fuelled
application
in
various
fields,
agriculture,
biomaterials,
the
food
industry,
drug
delivery,
tissue
engineering,
regenerative
medicine.
combination
nanoparticles,
specifically
Mesoporous
Silica
Nanoparticles
(MSNs),
have
elevated
these
composites
to
next
level,
since
MSNs
could
improve
hydrogel
mechanical
ability
encapsulate
controlled
release
great
amounts
different
therapeutic
agents,
responsiveness
a
variety
external
internal
stimuli.
In
this
review,
main
features
both
introduced,
followed
by
discussion
hydrogels-MSNs
structures
an
overview
use
applications,
delivery
technologies
engineering.
Nanomaterials,
Journal Year:
2023,
Volume and Issue:
13(18), P. 2518 - 2518
Published: Sept. 8, 2023
Three-dimensional
(3D)
printing
technology
has
become
a
popular
tool
to
produce
complex
structures.
It
great
potential
in
the
regenerative
medicine
field
customizable
and
reproducible
scaffolds
with
high
control
of
dimensions
porosity.
This
study
was
focused
on
investigation
new
biocompatible
biodegradable
3D-printed
suitable
mechanical
properties
assist
tendon
ligament
regeneration.
Polylactic
acid
(PLA)
were
reinforced
0.5
wt.%
functionalized
graphite
nanoplatelets
decorated
silver
nanoparticles
((f-EG)+Ag).
The
functionalization
graphene
carried
out
strengthen
interface
polymer.
(f-EG)+Ag
exhibited
antibacterial
against
Staphylococcus
aureus
(S.
aureus)
Escherichia
coli
(E.
coli),
an
important
feature
for
healing
process
prevention
bacterial
infections.
scaffolds'
structure,
biodegradation,
assessed
confirm
their
suitability
ligamentregeneration.
All
surface
nanoroughness
created
during
printing,
which
increased
by
filler
presence.
wet
state
dynamic
analysis
proved
that
incorporation
reinforcement
led
increase
storage
modulus,
compared
neat
PLA.
cytotoxicity
assays
using
L929
fibroblasts
showed
biocompatible.
PLA+[(f-EG)+Ag]
also
loaded
human
tendon-derived
cells
capability
maintain
tenogenic
commitment
gene
expression
specific
tendon/ligament-related
markers.
results
demonstrate
application
these
nanocomposite
Small Structures,
Journal Year:
2024,
Volume and Issue:
5(5)
Published: March 29, 2024
Surgical
sutures
are
necessary
for
the
rotator
cuff
(RC)
repair
to
reconnect
torn
and
degenerating
tendon
its
footprint.
Early‐stage
immunomodulation,
angiogenesis,
progressive
mechanobiological
response
encourage
complex
healing
processes
involving
micro‐nano
dimensional
reconstruction,
including
tendon‐bone
interface
integration
remodeling.
However,
commercially
available
with
mismatched
micrometer‐scale
diameters
resulted
in
biological
deficiencies,
severely
impeding
RC
regeneration.
We
developed
a
bionic
functional
surgical
suture
(SS)
helical
hierarchical
structures
using
nano‐
micro‐Poly
(DL‐lactide‐co‐glycolide)
(PLGA)
yarns
(ny),
which
was
subsequently
crosslinked
situ
temporary
chemotactic
(TC)
layer
of
physiological
fibrin
networks
(TC‐nySS).
The
TC‐nySS
has
both
advantages:
1)
biomimetic
showed
degradation
behavior,
inducing
incremental
repaired
tissues;
2)
outer
TC
biochemical
modification
by
supplied
dual‐functions
angiogenesis
immunomodulation
at
early
stage,
resulting
timely
vascularization
inflammatory
regressions
due
superior
behavior
constructs.
Consequently,
structural
designs
that
elicit
process‐matching
responses
tailored
regeneration
successfully
achieved
processes,
remodelling.
