Cited by Nanomedicines as a cutting-edge solution to combat antimicrobial resistance

Comparison of antibacterial activity and cytotoxicity of silver nanoparticles and silver-loaded montmorillonite and saponite DOI

Adrián Gil-Korilis,

Mihail Cojocaru,

Melibea Berzosa

et al.

Applied Clay Science, Journal Year: 2023, Volume and Issue: 240, P. 106968 - 106968

Published: May 5, 2023

Although silver nanoparticles are known for their antibacterial activity, little research has been carried out on what synthesis method provides the most effective particles. In this study, were synthesised via chemical reduction by using nitrate as precursor, ascorbic acid reducing agent and sodium citrate stabilising agent. The solutions adjusted to several pH values employing hydroxide, citric or nitric acid. Dynamic light scattering absorption spectra in ultraviolet/visible region characterisation revealed that adjust produced more varied larger particle sizes. Then, supported montmorillonite saponite through wet impregnation ion exchange methods. Scanning electron microscopy, energy-dispersive X-ray spectroscopy transmission microscopy confirmed successfully loaded onto clay minerals. Next, activity of samples was evaluated against Escherichia coli Staphylococcus aureus determining minimum inhibitory concentrations bactericidal concentrations. free did not show any at 125 mg/L. contrast, silver-loaded obtained with a higher content displayed strongest effect. Finally, cytotoxicity determined GM07492-A cell line an XTT colorimetric assay. calculated IC50 barely toxic. Thus, minerals here promising materials high-grade safety profile.

Language: Английский

Citations

Machine learning in antibacterial discovery and development: A bibliometric and network analysis of research hotspots and trends DOI

Karel Diéguez‐Santana, Humberto González‐Díaz

Computers in Biology and Medicine, Journal Year: 2023, Volume and Issue: 155, P. 106638 - 106638

Published: Feb. 7, 2023

Language: Английский

Citations

Ligand-based surface engineering of nanomaterials: Trends, challenges, and biomedical perspectives DOI

Ragini Singh, Sangly P. Srinivas,

Mamta Kumawat

et al.

OpenNano, Journal Year: 2023, Volume and Issue: 15, P. 100194 - 100194

Published: Nov. 1, 2023

Biomedical applications of nanomaterials, especially in diagnosing, management, and treatment - diseases are evolving. However, nanotoxicity remains a major challenge availing the full biomedical potential engineered nanomaterials. Nevertheless, recent advancements field have suggested that smart engineering targeting ligands presence biomolecules on surface nanomaterials can reduce through differential affinity, enhanced biocompatibility, efficient internalization. Further, certain ligand-functionalized permit their tracking cells tissues over prolonged period time, making them suitable for nanomedicine applications. In this seminal review, range strategies, which been employed functionalization using various confer amide / hydrazone bonds, thiol binding, silanization evaluated. The challenges, impact cellular uptake, drug targeting, molecular imaging, biocompatibility also discussed. Finally, aspects recommendations ligand-based detailed future

Language: Английский

Citations

Gold nanoparticles antibacterial activity: Does the surface matter? DOI

Marwan M. Sa'ed,

Raphael D. Ayivi, Jianjun Wei

et al.

Colloids and Interface Science Communications, Journal Year: 2024, Volume and Issue: 62, P. 100804 - 100804

Published: Sept. 1, 2024

Language: Английский

Citations

Nanomedicines as a cutting-edge solution to combat antimicrobial resistance DOI

Raghu Solanki, Nilesh Makwana, Rahul Kumar

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(45), P. 33568 - 33586

Published: Jan. 1, 2024

Antimicrobial mechanism of nanomaterials to combat AMR.

Language: Английский

Citations