Veterinary Sciences,
Journal Year:
2024,
Volume and Issue:
11(12), P. 675 - 675
Published: Dec. 22, 2024
A
total
of
640
one-day-old
Cobb
500
MV
×
FF
mixed
broilers
were
randomly
assigned
to
one
four
experimental
treatments
with
replicates
per
treatment
and
40
birds
replicate
for
32
days.
The
consisted
a
basal
diet
(control
group),
+
0.02%
zinc
bacitracin
(AGP
0.2%
G.
lucidum
powder
(GLP;
GLP
0.3%
(0.3%
group).
results
showed
that
dietary
supplementation
increased
body
weight
compared
the
control
groups,
decreased
feed
conversion
ratio
(FCR)
group,
during
19–32
days
(p
<
0.05).
intake
was
lower
0.05)
in
both
groups
AGP
group
1–8
1–32
group.
Additionally,
FCR
(0.2%)
Moreover,
caeca
broiler
chickens
had
higher
abundance
lactic
acid
bacteria
(LAB).
Supplementation
additives
GLP)
relative
thymus,
no
effect
on
bursa
Fabricius
spleen.
However,
serum
IgM
concentration,
while
supplementing
dose
(0.3%)
ash
content
tibia.
findings
indicate
is
recommended
as
natural
growth
promoter
replace
apparently
normal
chickens.
Nutrients,
Journal Year:
2025,
Volume and Issue:
17(8), P. 1307 - 1307
Published: April 9, 2025
Hericium
erinaceus,
commonly
known
as
lion’s
mane
mushroom,
has
gained
increasing
scientific
interest
due
to
its
rich
composition
of
bioactive
compounds
and
diverse
health-promoting
properties.
This
narrative
review
provides
a
comprehensive
overview
the
nutritional
therapeutic
potential
H.
with
particular
focus
on
anti-inflammatory,
antioxidant,
antimicrobial
activities.
A
structured
literature
search
was
performed
using
databases
such
PubMed,
Scopus,
Science
Direct,
Web
Science,
Google
Scholar.
Studies
published
in
last
two
decades
focusing
erinaceus’
were
included.
The
chemical
erinaceus
includes
polysaccharides,
terpenoids
(hericenones
erinacines),
phenolic
compounds,
which
exhibit
potent
antioxidant
effects
by
scavenging
reactive
oxygen
species
(ROS)
inducing
endogenous
enzymes.
Additionally,
shows
promising
activity
against
bacterial
fungal
pathogens,
applications
combating
antibiotic-resistant
infections.
mushroom’s
capacity
stimulate
nerve
growth
factor
(NGF)
synthesis
highlighted
preventing
managing
neurodegenerative
diseases,
Alzheimer’s
Parkinson’s.
Advances
biotechnological
methods,
including
optimized
cultivation
techniques
novel
extraction
may
further
enhance
bioavailability
pharmacological
erinaceus.
Despite
findings,
clinical
validation
remains
limited.
Future
research
should
prioritize
large-scale
trials,
standardization
elucidation
pharmacokinetics
facilitate
integration
into
evidence-based
medicine.
functional
food,
nutraceutical,
adjunct
agent
highlights
need
for
interdisciplinary
collaboration
between
researchers,
clinicians,
regulatory
bodies.
Frontiers in Microbiology,
Journal Year:
2024,
Volume and Issue:
15
Published: Sept. 25, 2024
,
a
well-known
genus
in
the
Ganodermataceae
family,
has
caused
extinction
of
several
tree
species
due
to
its
pathogenicity.
This
study
explored
pathogenic
effect
newly
identified
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(13), P. 6877 - 6877
Published: June 22, 2024
Higher-fungi
xylotrophic
basidiomycetes
are
known
to
be
the
reservoirs
of
bioactive
metabolites.
Currently,
a
great
deal
attention
has
been
paid
exploitation
mycelial
fungi
products
as
an
innovative
alternative
in
crop
protection.
No
data
exist
on
mechanisms
behind
interaction
between
mushrooms’
glycopolymeric
substances
and
plants.
In
this
study,
effects
basidiomycete
metabolites
morphophysiological
biochemical
variables
wheat
plants
have
explored.
Wheat
(Triticum
aestivum
L.
cv.
Saratovskaya
29)
seedlings
were
treated
with
extracellular
polysaccharides
(EPSs)
isolated
from
submerged
cultures
twenty
strains
assigned
13
species
8
genera.
The
EPS
solutions
at
final
concentrations
15,
40,
80
mg/L
applied
followed
by
their
growth
for
10
days.
plant
samples,
biomass,
length
coleoptile,
shoot
root,
root
number,
rate
lipid
peroxidation
malondialdehyde
concentration,
content
hydrogen
peroxide,
total
phenols
measured.
peroxidase
superoxide
dismutase
activity
defined.
Most
preparations
improved
biomass
yields,
well
morphological
parameters
examined.
application
enhanced
activities
antioxidant
enzymes
decreased
oxidative
damage
lipids.
Judging
its
overall
effect
indices
redox
system
plants,
concentration
40
shown
most
beneficial
compared
other
concentrations.
This
study
proves
that
novel
bioformulations
based
mushroom
EPSs
can
developed
effective
antioxidative
response.
Phytostimulating
properties
found
give
grounds
consider
produced
active
component
capable
inducing
responses
stress.
Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(5), P. 985 - 985
Published: May 14, 2024
Pseudomonas
aeruginosa
is
an
opportunistic
pathogen
that
usually
causes
chronic
infections
and
even
death
in
patients.
The
treatment
of
P.
infection
has
become
more
challenging
due
to
the
prevalence
antibiotic
resistance
slow
pace
new
development.
Therefore,
it
essential
explore
non-antibiotic
methods.
A
strategy
involves
screening
for
drugs
target
quorum-sensing
(QS)
system.
QS
system
regulates
drug
aeruginosa.
In
this
study,
veratryl
alcohol
(VA)
was
found
as
effective
inhibitor
(QSI).
It
effectively
suppressed
expression
QS-related
genes
subsequent
production
virulence
factors
under
control
including
elastase,
protease,
pyocyanin
rhamnolipid
at
sub-inhibitory
concentrations.
addition,
motility
activity
biofilm
formation,
which
were
correlated
with
aeruginosa,
also
by
VA.
vivo
experiments
demonstrated
VA
could
weaken
pathogenicity
Chinese
cabbage,
Drosophila
melanogaster,
Caenorhabditis
elegans
models.
Molecular
docking,
combined
quintuple
mutant
analysis,
identified
mechanism
LasR
protein
las
mainly.
Moreover,
increased
susceptibility
conventional
antibiotics
tobramycin,
kanamycin
gentamicin.
results
firstly
demonstrate
a
promising
QSI
treat
caused
Molecules,
Journal Year:
2024,
Volume and Issue:
29(18), P. 4400 - 4400
Published: Sept. 16, 2024
The
prevalence
of
antimicrobial
resistance
reduces
the
effectiveness
drugs
in
prevention
and
treatment
infectious
diseases
caused
by
pathogens
such
as
bacteria,
fungi,
viruses.
Microbial
secondary
metabolites
have
been
recognized
important
sources
for
new
drug
discovery
development,
yielding
a
wide
range
structurally
novel
functionally
diverse
variety
that
are
considered
good
producers
drugs.
Bacteria
produce
compounds,
thus,
antibiotics
derived
from
natural
products
still
dominate
over
purely
synthetic
among
developed
introduced
last
four
decades.
Among
them,
Pseudomonas
aeruginosa
constitute
richly
source
substances
with
activity.
Therefore,
they
regarded
an
outstanding
resource
finding
bioactive
compounds.
exploration
compounds
plays
role
development
biomedical
research.
Reports
on
aeruginosa,
many
which
pharmacological
importance,
hold
great
promise
effective
against
microbial
infections
drug-resistant
pathogens.
In
this
review,
we
attempt
to
summarize
published
articles
twenty-five
years
(2000–2024)
aeruginosa.
