Nutrients,
Journal Year:
2024,
Volume and Issue:
16(12), P. 1938 - 1938
Published: June 19, 2024
Type
2
diabetes
is
a
disease
with
significant
health
consequences
for
the
individual.
Currently,
new
mechanisms
and
therapeutic
approaches
that
may
affect
this
are
being
sought.
One
of
them
association
type
microbiota.
Through
enteric
nervous
system
gut–microbiota
axis,
microbiota
affects
functioning
body.
It
has
been
proven
to
have
real
impact
on
influencing
glucose
lipid
metabolism
insulin
sensitivity.
With
dysbiosis,
there
increased
bacterial
translocation
through
disrupted
intestinal
barrier
inflammation
in
In
diabetes,
microbiota’s
composition
altered
with,
example,
more
abundant
class
Betaproteobacteria.
The
these
disorders
linked
involving
short-chain
fatty
acids,
branched-chain
amino
lipopolysaccharide,
among
others.
Interventions
focusing
gut
gaining
traction
as
promising
approach
management.
Studies
currently
conducted
effects
supply
probiotics
prebiotics,
well
fecal
transplantation,
course
diabetes.
Further
research
will
allow
us
fully
develop
our
knowledge
subject
possibly
best
treat
prevent
International Journal of Environmental Research and Public Health,
Journal Year:
2022,
Volume and Issue:
19(23), P. 15494 - 15494
Published: Nov. 22, 2022
A
balanced
microbiota
composition
is
requisite
for
normal
physiological
functions
of
the
human
body.
However,
several
environmental
factors
such
as
air
pollutants
may
perturb
composition.
It
noticeable
that
currently
around
99%
world’s
population
breathing
polluted
air.
Air
pollution’s
debilitating
health
impacts
have
been
studied
scrupulously,
including
in
gut
microbiota.
Nevertheless,
impact
on
other
microbiotas
body
less
understood
so
far.
In
present
review,
authors
summarized
and
discussed
recent
studies’
outcomes
related
to
pollution-driven
microbiotas’
dysbiosis
(including
oral,
nasal,
respiratory,
gut,
skin,
thyroid
microbiotas)
its
potential
multi-organ
risks.
Nutrients,
Journal Year:
2023,
Volume and Issue:
15(3), P. 607 - 607
Published: Jan. 24, 2023
Gut
microbiota
is
the
largest
and
most
complex
microflora
in
human
body,
which
plays
a
crucial
role
health
disease.
Over
past
20
years,
bidirectional
communication
between
gut
extra-intestinal
organs
has
been
extensively
studied.
A
better
comprehension
of
alternative
mechanisms
for
physiological
pathophysiological
processes
could
pave
way
health.
Cardiovascular
disease
(CVD)
one
common
diseases
that
seriously
threatens
Although
previous
studies
have
shown
cardiovascular
diseases,
such
as
heart
failure,
hypertension,
coronary
atherosclerosis,
are
closely
related
to
microbiota,
limited
understanding
pathogenesis
leads
poor
effectiveness
clinical
treatment.
Dysregulation
inflammation
always
accounts
damaged
gastrointestinal
function
deranged
interaction
with
system.
This
review
focuses
on
characteristics
CVD
significance
regulation
during
whole
process.
In
addition,
strategies
prevent
treat
through
proper
its
metabolites
also
discussed.
Biomedicines,
Journal Year:
2023,
Volume and Issue:
11(9), P. 2480 - 2480
Published: Sept. 7, 2023
The
gut
microbiota
(GM)
plays
a
vital
role
in
human
health,
with
increasing
evidence
linking
its
imbalance
to
chronic
kidney
disease
and
end-stage
disease.
Although
the
exact
methods
underlying
kidney-GM
crosstalk
are
not
fully
understood,
interventions
targeting
GM
were
made
lay
three
aspects:
diagnostic,
predictive,
therapeutic
interventions.
While
these
show
promising
results
reducing
uremic
toxins
inflammation,
challenges
remain
form
of
patient-specific
variability,
potential
side
effects,
safety
concerns.
Our
understanding
GMs
is
still
evolving,
necessitating
further
research
elucidate
causal
relationship
mechanistic
interactions.
Personalized
focusing
on
specific
signatures
could
enhance
patient
outcomes.
However,
comprehensive
clinical
trials
needed
validate
approaches’
safety,
efficacy,
feasibility.
Frontiers in Pharmacology,
Journal Year:
2024,
Volume and Issue:
15
Published: March 18, 2024
Cardiovascular
diseases
are
among
the
leading
causes
of
mortality
worldwide,
with
dietary
factors
being
main
risk
contributors.
Diets
rich
in
bioactive
compounds,
such
as
(poly)phenols,
have
been
shown
to
potentially
exert
positive
effects
on
vascular
health.
Among
them,
resveratrol
has
gained
particular
attention
due
its
potential
antioxidant
and
anti-inflammatory
action.
Nevertheless,
results
humans
conflicting
possibly
interindividual
different
responses.
The
gut
microbiota,
a
complex
microbial
community
that
inhabits
gastrointestinal
tract,
called
out
responsible
for
modulating
biological
activities
phenolic
metabolites
humans.
present
review
aims
summarize
findings
from
clinical
trials
interventions
endothelial
outcomes
mechanisms
interesting
role
microbiota
metabolism
this
molecule
cardioprotective
metabolites.
randomized
controlled
show
contrasting
supplementation
biomarkers
without
dose-dependent
effect.
In
particular,
studies
which
was
integrated
using
food
sources,
i.e.,
red
wine,
reported
significant
although
content
was,
average,
much
lower
compared
tablet
supplementation,
while
other
often
extreme
resulted
null
findings.
experimental
suggest
exerts
through
modulation
various
antioxidant,
anti-inflammatory,
anti-hypertensive
pathways,
composition.
Recent
resveratrol-derived
metabolites,
piceatannol,
demonstrated
Moreover,
itself
improve
composition
toward
an
profile.
Considering
studies,
future
research
exploring
bidirectional
link
between
well
mediating
effect
cardiovascular
health
is
warranted.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(12), P. 1938 - 1938
Published: June 19, 2024
Type
2
diabetes
is
a
disease
with
significant
health
consequences
for
the
individual.
Currently,
new
mechanisms
and
therapeutic
approaches
that
may
affect
this
are
being
sought.
One
of
them
association
type
microbiota.
Through
enteric
nervous
system
gut–microbiota
axis,
microbiota
affects
functioning
body.
It
has
been
proven
to
have
real
impact
on
influencing
glucose
lipid
metabolism
insulin
sensitivity.
With
dysbiosis,
there
increased
bacterial
translocation
through
disrupted
intestinal
barrier
inflammation
in
In
diabetes,
microbiota’s
composition
altered
with,
example,
more
abundant
class
Betaproteobacteria.
The
these
disorders
linked
involving
short-chain
fatty
acids,
branched-chain
amino
lipopolysaccharide,
among
others.
Interventions
focusing
gut
gaining
traction
as
promising
approach
management.
Studies
currently
conducted
effects
supply
probiotics
prebiotics,
well
fecal
transplantation,
course
diabetes.
Further
research
will
allow
us
fully
develop
our
knowledge
subject
possibly
best
treat
prevent
