Investigation of the contamination rate of guinea fowl meats and its related samples by Escherichia coli using one health approach DOI Open Access

Stephen K.K. Monten,

Frederick Adzitey,

Juliana Bawah

et al.

Indonesian Food Science and Technology Journal, Journal Year: 2024, Volume and Issue: 8(1), P. 126 - 137

Published: Dec. 31, 2024

Guinea fowl meat is an important source of protein and other nutrients for humans. Their contamination by bacteria a threat to public health one approach tackling this warranted. This study investigated the rate guinea meats it related samples Escherichia coli using approach. It also antibiotic resistance from sources. A total 200 were randomly collected wet markets in Ghana sources was done procedures Bacteriological Analytical Manual USA-FDA. The disc diffusion method used test following confirmation polymerase chain reaction. highest processing knife (96.0%) least water main (28.0%). Faeces, floor, processor's hands, meat, washing table all contaminated with coli. partial fragment analysis uidA gene PCR yielded band ~147 bp isolates exhibited ceftriaxone (60.5%), but susceptibility azithromycin (94.7%). Intermediate gentamicin (34.2%). MAR index ranged 0.0 (resistant 0 antibiotic) 0.8 7 antibiotics) 24 different profiles. confirms that some market resistant antibiotics. Appropriate handling considering sale points are recommended prevent spread foodborne infections.

Language: Английский

Exploring the Scope of Traditional Chinese Medicinal Plants in battle of antibiotic resistance – A comprehensive review DOI Creative Commons
S. Bhunia, S. A. Mallick, A. Mondal

et al.

Pharmacological Research - Modern Chinese Medicine, Journal Year: 2025, Volume and Issue: 14, P. 100574 - 100574

Published: Jan. 15, 2025

Language: Английский

Citations

2
Antibiotic resistance and Nanotechnology: A narrative review DOI

Xunxian Zhu,

Qiuhua Tang,

Xiaohang Zhou

et al.

Microbial Pathogenesis, Journal Year: 2024, Volume and Issue: 193, P. 106741 - 106741

Published: June 11, 2024

Language: Английский

Citations

8
Preliminary Multi-Omics Insights into Green Alternatives to Antibiotics: Effects of Pulsatilla chinensis, Acer truncatum, and Clostridium butyricum on Gut Health and Metabolic Regulation in Chickens DOI Creative Commons

Lin Sun,

Zhijun Wang,

Shidi Qin

et al.

Animals, Journal Year: 2025, Volume and Issue: 15(9), P. 1262 - 1262

Published: April 29, 2025

Antibiotic resistance has become a global health concern, driving the need for sustainable alternatives in animal husbandry. This study explores potential of natural feed additives as viable solution to enhance poultry growth and while reducing reliance on antibiotics. Chinese herbal medicines probiotics have been widely studied green, healthy, safe antibiotic livestock production. A total 120 chickens were randomly divided into four groups: control group three treatment groups supplemented with 1% Pulsatilla chinensis powder, 3% fresh Acer truncatum, or Clostridium butyricum. The results showed that powder significantly increased gamma-glutamylcysteine (p < 0.05), UDP-N-acetylglucosamine tyramine 0.01), leucine 0.05). truncatum notably altered cecal metabolites, including L-tyrosine α-ketoisovaleric acid myristoleic glutathione PGA1 butyricum modified metabolites such L-glutamine riboflavin L-Carnitine ergocalciferol α-tocotrienol

Language: Английский

Citations

0
In vitro anti-Helicobacter pylori activity and the underlining mechanism of an empirical herbal formula – Hezi Qingyou DOI Creative Commons
Zhong Feng, Hui Li, Yajie Hao

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: Feb. 19, 2024

Background Helicobacter pylori ( H. ) is thought to primarily colonize the human stomach and lead various gastrointestinal disorders, such as gastritis gastric cancer. Currently, main eradication treatment triple or quadruple therapy centered on antibiotics. Due antibiotic resistance, rate of decreasing gradually. Therefore, searching for anti- drugs from herbal sources has become a strategy treatment. Our team proposed Hezi Qingyou Formula (HZQYF), composed Chebulae Fructus, Ficus hirta Vahl Cloves, studied its activity mechanism. Methods Chemical components HZQYF were using UHPLC–MS/MS HPLC. Broth microdilution method agar dilution used evaluate HZQYF’s antibacterial activity. The effects expression adhesion genes alpA , alpB babA ), urease ureE ureF flagellar flaA, flaB explored Reverse Transcription-quantitative Polymerase Chain Reaction (RT-qPCR) technology. Effects morphology permeability extracellular membrane scanning electron microscopy (SEM) N-phenylnaphthalen-1-amine (NPN) uptake. Effect was kinetics analysis in vitro . Immunofluorescence staining examine effect adhesion. Western blot cagA protein. Results Minimum inhibitory concentration (MIC) values formula against clinical strains standard 80–160 μg/mL, minimum bactericidal (MBC) 160–320 μg/mL. could down-regulate alp A, flaA change increase permeability, decrease Conclusion Present studies confirmed that had promising activities demonstrated possible mechanism action by down-regulating bacterial adhesion, urease, gene expression, which provided scientific bases further investigations.

Language: Английский

Citations

3
Comparison of Chinese medicine additives for antibiotic resistance risks in the Wuding chickens under high stocking density: Advantages and drawbacks DOI
Honggang Hu, Ying Huang,

Changyou Shi

et al.

Journal of Cleaner Production, Journal Year: 2024, Volume and Issue: 469, P. 143152 - 143152

Published: July 14, 2024

Language: Английский

Citations

2
Rapid Self-Disinfection Nanofiber Film Based on AgPd Hollow Nanospheres DOI

Shuai Pi,

Minghui Zhan,

Bianhua Liu

et al.

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: 7(7), P. 7408 - 7420

Published: March 21, 2024

Bacterial infection caused by pathogenic bacteria can occur in the human respiratory tract, skin, blood, and other parts, seriously threatening life health. There is an urgent need to develop a durable, internal, fast, effective sterilization protective mask limit proliferation rapid spread of microorganisms, thereby ensuring health issues. Therefore, we have ingeniously designed spherical hollow silver–palladium nanoalloy-based polyacrylonitrile nanofiber film (AgPd-PAN film) displacement reaction electrospinning technology, which exhibited outstanding quad-mode synergistic antibacterial effect. Pd-modified Ag nanospheres, especially AgPd0.4, possessed strong inherent ability generate reactive oxygen species (ROS). Surprisingly, synthesized AgPd0.4 nanospheres showed excellent photothermal conversion performance (28.16%), oxidase-like was significantly enhanced under visible light irradiation, resulting 20% increase production 1O2. The prepared AgPd-PAN also performance, instantly rising 58.5 °C 1 min. Meanwhile, had prominent self-disinfection could completely kill within 3 h. Notably, once exposed sunlight, time drastically shortened 4 ROS, sharp rise solar irradiation temperature, release Ag+ contributed film. In addition, almost negligible biological toxicity were suitable for further application equipment. strategy great prospects timely mask.

Language: Английский

Citations

1
Revealing the antimicrobial potential of traditional Chinese medicine through text mining and molecular computation DOI Creative Commons
Meng‐Chi Chung, Li Su,

Chien-Lin Chen

et al.

Briefings in Bioinformatics, Journal Year: 2024, Volume and Issue: 26(1)

Published: Nov. 22, 2024

Abstract Traditional Chinese Medicine (TCM), with its extensive knowledge base documented in ancient texts, offers a unique resource for contemporary drug discovery, particularly combatting microbial infections. The success of antimalarial drugs like artemisinin and artesunate, derived from the TCM herb Artemisia annua L., exemplifies potential TCM-derived small molecules. This rich repository natural products intricate molecular structures could reveal novel compounds unexplored mechanisms action. Our study employs multifaceted approach that combines text mining, detailed textual analysis, modern antibacterial prediction methodologies to unlock remedies. We use external maps, which include databases known bioactive their targets, identify promising candidates. leverages both historical texts scientific data explore therapeutic TCM. discovered patterns DiYu→ZeXie Kushen→ShengJiang potentially combat Grams-positive Grams-negative bacteria. utilized AntiBac-Pred online tool analyze chemical components herbs, integrating TCMDB@Taiwan graph. groups showed antimicrobial against resistant Staphylococcus simulans, while exhibited dual effects Bacillus subtilis. Exploring TCM’s numerous opportunities discovering therapeutically active compounds. synergistic approach, wisdom science, holds significant promise enhancing our ability infectious diseases. method pave way new era personalized medicine, addressing urgent need innovative treatments multidrug-resistant bacteria viruses.

Language: Английский

Citations

0
Investigation of the contamination rate of guinea fowl meats and its related samples by Escherichia coli using one health approach DOI Open Access

Stephen K.K. Monten,

Frederick Adzitey,

Juliana Bawah

et al.

Indonesian Food Science and Technology Journal, Journal Year: 2024, Volume and Issue: 8(1), P. 126 - 137

Published: Dec. 31, 2024

Guinea fowl meat is an important source of protein and other nutrients for humans. Their contamination by bacteria a threat to public health one approach tackling this warranted. This study investigated the rate guinea meats it related samples Escherichia coli using approach. It also antibiotic resistance from sources. A total 200 were randomly collected wet markets in Ghana sources was done procedures Bacteriological Analytical Manual USA-FDA. The disc diffusion method used test following confirmation polymerase chain reaction. highest processing knife (96.0%) least water main (28.0%). Faeces, floor, processor's hands, meat, washing table all contaminated with coli. partial fragment analysis uidA gene PCR yielded band ~147 bp isolates exhibited ceftriaxone (60.5%), but susceptibility azithromycin (94.7%). Intermediate gentamicin (34.2%). MAR index ranged 0.0 (resistant 0 antibiotic) 0.8 7 antibiotics) 24 different profiles. confirms that some market resistant antibiotics. Appropriate handling considering sale points are recommended prevent spread foodborne infections.

Language: Английский

Citations

0