Helicobacter pylori outer membrane vesicles and infected cell exosomes: new players in host immune modulation and pathogenesis DOI Creative Commons
Xiuping Wang,

Jianjun Wang,

Lingxiang Mao

et al.

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Dec. 12, 2024

Outer membrane vesicles (OMVs) and exosomes are essential mediators of host-pathogen interactions. Elucidating their mechanisms action offers valuable insights into diagnosing treating infectious diseases cancers. However, the specific interactions Helicobacter pylori ( H. ) with host cells via OMVs in modulating immune responses have not been thoroughly investigated. This review explores how these elicit inflammatory immunosuppressive environment, facilitate pathogen invasion cells, enable evasion defenses, thereby contributing to progression gastric extra-gastric disseminated through bloodstream. Furthermore, discusses challenges future directions for investigating exosomes, underscoring potential as therapeutic targets -associated diseases.

Language: Английский

The paradox of Helicobacter pylori: How does H. pylori infection protect against esophageal cancer? DOI Open Access
Erfan Banisefid, Ehsan Nasiri,

Seyedyashar Pourebrahimian Leilabadi

et al.

Annals of Medicine and Surgery, Journal Year: 2024, Volume and Issue: 86(12), P. 7221 - 7226

Published: Oct. 18, 2024

Language: Английский

Citations

0
Helicobacter pylori-targeted AI-driven vaccines: a paradigm shift in gastric cancer prevention DOI Creative Commons

Zhiwei Tu,

Youtao Wang,

Junze Liang

et al.

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Nov. 28, 2024

, a globally prevalent pathogen Group I carcinogen, presents formidable challenge in gastric cancer prevention due to its increasing antimicrobial resistance and strain diversity. This comprehensive review critically analyzes the limitations of conventional antibiotic-based therapies explores cutting-edge approaches combat

Language: Английский

Citations

0
Helicobacter pylori outer membrane vesicles and infected cell exosomes: new players in host immune modulation and pathogenesis DOI Creative Commons
Xiuping Wang,

Jianjun Wang,

Lingxiang Mao

et al.

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Dec. 12, 2024

Outer membrane vesicles (OMVs) and exosomes are essential mediators of host-pathogen interactions. Elucidating their mechanisms action offers valuable insights into diagnosing treating infectious diseases cancers. However, the specific interactions Helicobacter pylori ( H. ) with host cells via OMVs in modulating immune responses have not been thoroughly investigated. This review explores how these elicit inflammatory immunosuppressive environment, facilitate pathogen invasion cells, enable evasion defenses, thereby contributing to progression gastric extra-gastric disseminated through bloodstream. Furthermore, discusses challenges future directions for investigating exosomes, underscoring potential as therapeutic targets -associated diseases.

Language: Английский

Citations

0