Cited by Advances in Manganese-based nanomaterials for cancer therapy via regulating Non-Ferrous ferroptosis

A Systematic Review on Advances in Management of Oxidative Stress-Associated Cardiovascular Diseases DOI

Soyeon Jin,

Peter M. Kang

Antioxidants, Journal Year: 2024, Volume and Issue: 13(8), P. 923 - 923

Published: July 29, 2024

Oxidative stress plays a significant role in the pathogenesis of cardiovascular diseases, such as myocardial ischemia/reperfusion injury, atherosclerosis, heart failure, and hypertension. This systematic review aims to integrate most relevant studies on oxidative management diseases. We searched literatures PubMed database using specific keywords. put emphasis those manuscripts that were published more recently higher impact journals. reviewed total 200 articles. examined current managements including supplements like resveratrol, vitamins C E, omega-3 fatty acids, flavonoids, coenzyme-10, which have shown antioxidative properties potential benefits. In addition, we pharmacological treatments newly discovered antioxidants nanoparticles show effects targeting pathways. Lastly, biomarkers, soluble transferrin receptor, transthyretin, cystatin evaluating antioxidant status identifying risk. By addressing mechanisms, this paper emphasizes importance maintaining balance between oxidants progression is registered with International Platform Registered Systematic Review Meta-analysis Protocols (INPLASY), registration # INPLASY202470064.

Language: Английский

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Gastrodin prevents myocardial injury in sleep-deprived mice by suppressing ferroptosis through SIRT6 DOI

Yi Wu,

Yuping Miao,

Yin Cao

et al.

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2024, Volume and Issue: 397(11), P. 9111 - 9121

Published: June 19, 2024

Language: Английский

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Broadening horizons: research on ferroptosis in lung cancer and its potential therapeutic targets DOI

Guangpeng Gao, Xindi Zhang

Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 16

Published: Jan. 23, 2025

Ferroptosis is a novel form of cell death distinct from traditional mechanisms, characterized by the accumulation iron ions and production lipid peroxides. It not only affects survival tumor cells but also closely linked to changes in microenvironment. Lung cancer one leading malignancies worldwide terms incidence mortality, its complex biological mechanisms resistance make treatment challenging. Recent studies have shown that ferroptosis plays key role onset progression lung cancer, with intricate regulatory influencing development response therapy. As research into deepens, related molecular pathways, such as glutamate metabolism, antioxidant defense, been gradually revealed. However, clinical practice, ferroptosis-based therapeutic strategies for are still their early stages. Challenges remain, including incomplete understanding specific ferroptosis, insufficient on factors, limited insight interactions within Therefore, effective modulation enhance remains an urgent issue. This review summarizes analyzes factors interaction microenvironment, further explores potential targeting ferroptosis. By synthesizing latest research, this paper aims provide new perspectives directions treatment, goal advancing applications.

Language: Английский

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Mechanistic role of environmental toxicants in inducing cellular ferroptosis and its associated diseases DOI

Hong Chen,

Bingchun Liu,

Peixin Xu

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 298, P. 118269 - 118269

Published: May 10, 2025

Language: Английский

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Advances in Manganese-based nanomaterials for cancer therapy via regulating Non-Ferrous ferroptosis DOI

Dipa Kusi,

Yan Sun,

Chenguang Liu

et al.

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 669, P. 125101 - 125101

Published: Dec. 19, 2024

Language: Английский

Citations