Model prediction of suicidal behavior in first hospitalization patients with major depression disorder: a cross-sectional study based on a large sample DOI Creative Commons

Suoya Hu,

Lin Zhang, Xuebing Liu

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: June 2, 2023

Abstract Background Major depressive disorder (MDD) is one of the common and major causes suicidal behavior (SB). The purpose this study was to determine prevalence SB its factors influence among first hospitalized MDD patients in China, develop a predictive model for target population. Methods This recruited 981 with who were experiencing their hospitalization. patients' socio-pathological general clinical data gathered, along metabolic parameters thyroid function. In addition, assessed depressive, anxiety, psychotic symptoms, as well severity disease. Results Our revealed 13.46% patients. A variety symptom scores indicators identified risk SB, based on we further obtained good ability differentiate SB. Conclusion provides validated population suggests that addressed our could be better used early implementation preventive measures.

Language: Английский

Alexithymia in Chinese patients with chronic schizophrenia: Prevalence, clinical correlates, and relationship with neurocognition and empathy DOI Open Access
Pu Peng, Dongmei Wang, Qianjin Wang

et al.

Asia-Pacific Psychiatry, Journal Year: 2023, Volume and Issue: 15(4)

Published: Aug. 28, 2023

Alexithymia is highly prevalent and strongly related to adverse consequences in patients with schizophrenia. However, its associated factors remain largely unexplored. The present study aimed determine the prevalence of alexithymia association sociocultural characteristics, clinical symptoms, neurocognition, empathy 854 Chinese schizophrenia.Demographic information was collected through a self-designed questionnaire. assessed by Toronto Scale (TAS-20). We via following instruments: Positive Negative Syndrome Scale, Repeatable Battery for Assessment Neuropsychological Status, Interpersonal Reactivity Index. A multiple logistic regression model conducted independent correlates alexithymia.Approximately one-third (n = 277, 32%) schizophrenia had alexithymia. Patients significantly more severe negative impairment than without Being male, personal distress, empathic concern, language functioning were independently alexithymia.Our findings demonstrate high strong empathy, which calls timely screening intervention Targeting impaired function, affective might help reduce consequences.

Language: Английский

Citations

11
Comprehensive view of suicide: A neuro-immune-endocrine approach DOI
María Dolores Ponce-Regalado, Enrique Becerril‐Villanueva, José Luis Maldonado-García

et al.

World Journal of Psychiatry, Journal Year: 2025, Volume and Issue: 15(2)

Published: Jan. 14, 2025

Suicide is defined as the act of a person attempting to take their own life by causing death. complex phenomenon that influenced multitude factors, including psychosocial, cultural, and religious aspects, well genetic, biochemical, environmental factors. From biochemical perspective, it crucial consider communication between endocrine, immune, nervous systems when studying etiology suicide. Several pathologies involve bidirectional peripheral activity central system action molecules such cytokines, hormones, neurotransmitters. These humoral signals, present in optimal quantities, are responsible for maintaining physiological homeostasis, mood states. Stress elevates cortisol proinflammatory cytokines levels alter neurotransmitters balance, thereby increasing risk developing psychiatric disorder subsequently suicidal behavior. This review provides an integrative perspective about neurochemical, immunological, endocrinological disturbances associated with behavior, particular focus on those alterations may serve potential markers and/or indicators state preceding tragic act.

Language: Английский

Citations

0
WITHDRAWN: Model prediction of suicidal behavior in first hospitalization patients with major depression disorder: a cross-sectional study based on a large sample DOI Creative Commons

Suoya Hu,

Lin Zhang, Xuebing Liu

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 18, 2025

Abstract The full text of this preprint has been withdrawn by the authors since they no longer stand findings/conclusions work. Therefore, do not wish work to be cited as a reference. Questions should directed corresponding author.

Language: Английский

Citations

0
Associations between multiple sleep dimensions and suicide and non-suicidal self-injury: a cross-sectional study of 3828 Chinese young people DOI

Qiuyuan Chen,

Lu Gong, Yalin Song

et al.

Social Psychiatry and Psychiatric Epidemiology, Journal Year: 2024, Volume and Issue: unknown

Published: May 23, 2024

Language: Английский

Citations

3
Sex-differential association of suicide attempts with thyroid dysfunction in first-episode and drug-naïve young major depressive disorder patients with comorbid anxiety DOI Creative Commons
Gang Ye, Ying Yuan, Zhe Li

et al.

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: Aug. 22, 2023

This study aimed to explore sex differences in the relationship between thyroid function indicators and suicide attempts first-episode drug-naïve young major depressive disorder (MDD) patients with comorbid anxiety (MDA). A total of 917 MDD (aged 18-35 years) were recruited. The Hamilton depression rating scale (HAMD-17), (HAMA), positive negative syndrome (PANSS) subscale clinical global impression severity (CGI-S) used. 467 classified as MDA. prevalence was 31.3% MDA patients, which significantly higher than that (7.3%) without anxiety. Compared attempts, older, had a later age onset, HAMD-17, HAMA, PANSS symptom scores, well TSH, TgAb TPOAb levels. For male TSH levels independently associated attempts. female CGI-S score Our results suggest can predict have differences.

Language: Английский

Citations

8
Inter-relationships of insomnia and psychiatric symptoms with suicidal ideation among patients with chronic schizophrenia: A network perspective DOI
Pu Peng, Qianjin Wang, Yanan Zhou

et al.

Progress in Neuro-Psychopharmacology and Biological Psychiatry, Journal Year: 2023, Volume and Issue: 129, P. 110899 - 110899

Published: Nov. 23, 2023

Language: Английский

Citations

6
Suicidal ideation in Chinese patients with chronic schizophrenia: prevalence, clinical correlates, and relationship with alexithymia DOI
Yanan Zhou, Pu Peng, Ning Yuan

et al.

European Archives of Psychiatry and Clinical Neuroscience, Journal Year: 2023, Volume and Issue: 274(7), P. 1509 - 1516

Published: June 13, 2023

Language: Английский

Citations

5
Association between childhood maltreatment and suicidal ideation among Chinese patients with chronic schizophrenia: the mediating role of insomnia DOI Creative Commons
Yuzhu Hao, Pu Peng, Qianjin Wang

et al.

BJPsych Open, Journal Year: 2024, Volume and Issue: 10(3)

Published: May 1, 2024

Background Childhood maltreatment is a well-established transdiagnostic risk factor for suicidal ideation; however, previous studies on their association in schizophrenia have produced highly varied results. Moreover, the mechanism linking childhood and suicide ideation remains unclear schizophrenia. Aims This cross-sectional study aimed to investigate between people with tested whether insomnia mediated this relationship. Method Positive Negative Syndrome Scale (PANSS), Insomnia Severity Index (ISI), Trauma Questionnaire – Short Form Beck Suicidal Ideation Inventory were employed. Logistic regression mediation analysis performed. Results (a) The prevalence of ideation, insomnia, sexual abuse, emotional neglect, physical abuse neglect was 10% ( n = 61), 18% 111), 11% 68), 25% 153), 6.3% 39), 17% 106) 39% 239), respectively. In all, 52% 320) reported maltreatment; (b) patients demonstrated higher maltreatment. PANSS depression factor, ISI, lifetime attempts independently associated (c) partially effects completely ideation. Conclusion Our calls formal assessments schizophrenia, which might help identify early. addition, interventions targeting reduce among who experience

Language: Английский

Citations

1
Exploring core symptoms of alcohol withdrawal syndrome in alcohol use disorder patients: a network analysis approach DOI Creative Commons
Guanghui Shen,

Yu-Hsin Chen,

Yu‐Yu Wu

et al.

Frontiers in Psychiatry, Journal Year: 2024, Volume and Issue: 15

Published: Aug. 29, 2024

Background Understanding the interplay between psychopathology of alcohol withdrawal syndrome (AWS) in use disorder (AUD) patients may improve effectiveness relapse interventions for AUD. Network theory mental disorders assumes that persist not a common functional disorder, but from sustained feedback loop symptoms, thereby explaining persistence AWS and high rate The current study aims to establish network AWS, identify its core symptoms find bridges which are intervention target relieve break self-maintaining cycle Methods Graphical lasso were constructed using psychological 553 AUD patients. Global structure, centrality indices, cluster coefficient, bridge symptom used transmission pathways different clusters. Results results revealed that: (1) constitutes stable with stability coefficient (CS) 0.21-0.75. (2) Anger (Strength = 1.52) hostility 0.84) emerged as highest low clustering coefficient. (3) Hostility mediates aggression anxiety; anger impulsivity respectively. Conclusions be considered best targets researching treating AWS. anxiety, impulsiveness independent related dimensions, suggesting neurobiological bases involved play similar role syndrome.

Language: Английский

Citations

1
Prevalence and related factors of first-time suicide attempts in the past 14 days in Chinese adult patients with first-episode drug-naïve major depressive disorder DOI Creative Commons

Xiaoyin Cong,

Tian Zhang,

Rongrong Bian

et al.

Frontiers in Psychiatry, Journal Year: 2024, Volume and Issue: 15

Published: March 22, 2024

Background This study aimed to identify socio-demographic, physiologic, and psychologic related factors of the first-time suicide attempt (FSA) in past 14 days Chinese adult patients with first-episode drug-naïve (FEDN) major depressive disorder (MDD). Methods A total 1718 FEDN MDD were enrolled this cross-sectional survey. Depression, anxiety symptoms, attempts assessed. Additionally, biological samples collected measured, while Logistic regression analysis was employed explore risk for FSA among patients. Results Among attempters, 12.11% (208 out 1718) reported experiencing days. showed that included more severe symptoms (OR=1.37, 95%CI: 1.28-1.48, p <0.001), higher levels cholesterol (TC) (OR=1.42, 1.13-1.77, =0.003), elevated thyroid-stimulating hormone (TSH) (OR=1.13, 1.03-1.25, =0.01). The model exhibited good discriminatory power an area under curve (AUC) 0.82. Conclusion TSH TC are likely develop These short-term (in days) may serve as indicators early intervention.

Language: Английский

Citations

0